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2000:
Parshikov I A; Freeman J P; Lay J O; Beger R D; Williams A J; Sutherland J B
Microbiological transformation of enrofloxacin by the fungus Mucor ramannianus.
Applied and environmental microbiology 2000;
66(
6):.
Enrofloxacin metabolism by Mucor ramannianus was investigated as a model for the biotransformation of veterinary fluoroquinolones. Cultures grown in sucrose-peptone broth were dosed with enrofloxacin. After 21 days, 22% of the enrofloxacin remained. Three metabolites were identified: enrofloxacin N-oxide (62% of the total absorbance), N-acetylciprofloxacin (8.0%), and desethylene-enrofloxacin (3.5%).
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