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2002:
Harty John T; Badovinac Vladimir P
Influence of effector molecules on the CD8(+) T cell response to infection.
Current opinion in immunology 2002;
14(
3):.
Expansion and contraction of antigen-specific CD8(+) T cells after infection or vaccination results in stable memory. Recent evidence demonstrates that anti-microbial effector molecules such as perforin and IFN-gamma regulate specific aspects of CD8(+) T cell homeostasis by mechanisms that may be dependent or independent of pathogen clearance.
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