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2003Chiocca E Antonio; Aghi Manish; Fulci Giulia
Viral therapy for glioblastoma.
Cancer journal (Sudbury, Mass.) 2003;9(3):167-79.
Malignant gliomas remain amongst the most difficult cancer to treat. Viral-based gene therapies have been employed for the last decade in preclinical and clinical modes as a novel treatment modality. In this review, such therapies are summarized. The overwhelming majority of clinical studies point one to conclude that methodologies that will increase tumor infection/transduction will lead to enhanced therapeutic results.

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