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2005Matsunaga Takuya; Murase Kazuyuki; Yoshida Makoto; Fujimi Akihito; Iyama Satoshi; Kuribayashi Kageaki; Sato Tsutomu; Kogawa Katsuhisa; Hirayama Yasuo; Sakamaki Sumio; Kohda Kyuhei; Niitsu Yoshiro
Donor cell derived acute myeloid leukemia after allogeneic cord blood transplantation in a patient with adult T-cell lymphoma.
American journal of hematology 2005;79(4):294-8.
We report a patient with adult T-cell lymphoma who developed acute myeloid leukemia (AML) after allogeneic cord blood transplantation (CBT). Fluorescence in situ hybridization (FISH) studies and molecular analysis using short tandem repeat (STR) sequences proved the AML to be of donor origin. Although 25 cases of donor cell leukemia (DCL) occurring after allogeneic bone marrow transplantation have previously been reported, there have been no reports of DCL after CBT. This case is the first-reported DCL patient after CBT.

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