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2005:
Williams Tatjana; Joseph Biju; Beier Dagmar; Goebel Werner; Kuhn Michael
Response regulator DegU of Listeria monocytogenes regulates the expression of flagella-specific genes.
FEMS microbiology letters 2005;
252(
2):.
An isogenic mutant of Listeria monocytogenes EGD with a deletion of the response regulator gene degU showed a lack of motility due to the absence of flagella. In the present study, we used two-dimensional gel electrophoresis, mass-spectrometry and microarray analyses to identify the listerial genes that depend on DegU for expression. We found that the two L. monocytogenes operons encoding flagella-specific genes and the monocistronically transcribed flaA gene are positively regulated by DegU at 24 degrees C, but are not expressed at 37 degrees C.
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