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2005Gurgey Aytemiz; Secmeer Gulten; Tavil Betul; Ceyhan Mehmet; Kuskonmaz Baris; Cengiz Bulent; Ozen Hasan; Kara Ates; Cetin Mualla; Gumruk Fatma
Secondary hemophagocytic lymphohistiocytosis in Turkish children.
The Pediatric infectious disease journal 2005;24(12):1116-7.
Between January 1998 and January 2005, a total of 18 children 2 weeks-72 months of age were diagnosed as having secondary hemophagocytic lymphohistiocytosis. The frequency of secondary hemophagocytic lymphohistiocytosis among total hospitalized patients during this period was 0.05% (18 of 34,250). Of the 18 patients, 8 (44.5%) had bacterial infections; cytomegalovirus and Epstein-Barr virus infections were present in 5 (28%) and 1 (5.5%), patient, respectively. Leishmaniasis was diagnosed in 2 patients (11%), and herpes simplex virus was diagnosed in 2 patients (11%). Six patients died during treatment, and 1 patient was lost to follow-up. The survival rate was 61%.

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