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2006Motl Robert W; O'connor Patrick J; Tubandt Leslie; Puetz Tim; Ely Matthew R
Effect of caffeine on leg muscle pain during cycling exercise among females.
Medicine and science in sports and exercise 2006;38(3):598-604.
PURPOSE: This double-blind, within-subjects experiment examined the effects of ingesting two doses of caffeine on perceptions of leg muscle pain during moderate-intensity cycling exercise among females. METHODS: Low-caffeine-consuming college-aged females (N = 11) ingested one of two doses of caffeine (5 or 10 mg x kg(-1) body weight) or a placebo and 1 h later completed 30 min of cycling on an ergometer at approximately 60% VO2peak. The conditions were completed in a counterbalanced order. Perceptions of leg muscle pain as well as power output, heart rate, systolic blood pressure, and oxygen consumption (VO2) were recorded during exercise. RESULTS: Caffeine had a significant effect on leg muscle pain ratings [F (2,20) = 10.63, P = 0.001, n2 = 0.52]. The mean pain intensity scores during exercise after ingesting 10 mg x kg(-1) body weight caffeine, 5 mg x kg(-1) body weight caffeine, and placebo were 1.6 +/- 1.1, 1.3 +/- 0.7, and 2.4 +/- 1.1, respectively. CONCLUSION: The results support that caffeine ingestion has a large effect on reducing leg muscle pain during exercise among females, but this effect does not appear to be dose-dependent between 5 and 10 mg.kg body weight caffeine.

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