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2006:
Xiao Wei-Lie; Pu Jian-Xin; Chang Ying; Li Xiao-Li; Huang Sheng-Xiong; Yang Liu-Meng; Li Li-Mei; Lu Yang; Zheng Yong-Tang; Li Rong-Tao; Zheng Qi-Tai; Sun Han-Dong
Sphenadilactones A and B, two novel nortriterpenoids from Schisandra sphenanthera.
Organic letters 2006;
8(
7):.
[structure: see text] Two novel nortriterpenoid compounds, sphenadilactones A (1) and B (2), have been isolated from the leaves and stems of Schisandrasphenanthera. The structural elucidation of 1 and 2 was accomplished by extensive NMR analysis. The relative stereochemistry of 1 was established by single-crystal X-ray crystallography. Both compounds were tested for their cytotoxicities against K562, A549, and HT-29, and compound 1 was further tested for its anti-HIV-1 activity.
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