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2006:
Ferroni Agnès; Vu-Thien Hoang; Lanotte Philippe; Le Bourgeois Muriel; Sermet-Gaudelus Isabelle; Fauroux Brigitte; Marchand Sophie; Varaigne Françoise; Berche Patrick; Gaillard Jean-Louis; Offredo Catherine
Value of the chlorhexidine decontamination method for recovery of nontuberculous mycobacteria from sputum samples of patients with cystic fibrosis.
Journal of clinical microbiology 2006;
44(
6):.
The chlorhexidine method was compared to the N-acetyl-l-cysteine-NaOH-oxalic acid decontamination method currently recommended for the recovery of nontuberculous mycobacteria (NTM) from patients with cystic fibrosis. Sputum samples (n = 827) treated with chlorhexidine yielded twice as many NTM-positive cultures as those treated by the reference method (54 [6.50%] versus 27 [3.25%]; P < 0.0001) despite a higher contamination rate (20% versus 14.2%; P = 0.0017).
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