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2006:
Sato Tsutomu; Matsunaga Takuya; Iyama Satoshi; Sakai Toshiro; Murase Kazuyuki; Sato Yasushi; Kobune Masayoshi; Takimoto Rishu; Kato Junji; Niitsu Yoshiro
[Enteropathy-type T-cell lymphoma with CD8 and CD56 expression]
[Rinsho ketsueki] The Japanese journal of clinical hematology 2006;
47(
7):.
A 54-year-old male presented at a previous hospital with abdominal pain, where the patient was diagnosed as having abdominal and retroperitoneal lymphadenopathies by CT scan, then, he was referred to our hospital for further examination. Upper gastrointestinal endoscopy showed a tumor formation in the second portion of the duodenum, and there were medium sized atypical lymphocytes in biopsy specimens of the tumor. Since the atypical lymphocytes in the biopsy specimens were positive for CD3, CD8, CD56 and CD103 by immunostain, and had a rearrangement of the T-cell receptor 7-chain, the patient was diagnosed as having enteropathy-type T-cell lymphoma (ETL). Although ETL usually occurs as a complication of celiac disease, malabsorption and anti-gliadin antibodies, which are normally present in celiac disease, were not observed in this patient.
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