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2006Xu Gang; Hou Ai-Jun; Wang Rui-Rui; Liang Guang-Yu; Zheng Yong-Tang; Liu Ze-Yuan; Li Xiao-Li; Zhao Yu; Huang Sheng-Xiong; Peng Li-Yan; Zhao Qin-Shi
Przewalskin A: A new C23 terpenoid with a 6/6/7 carbon ring skeleton from Salvia przewalskii maxim.
Organic letters 2006;8(20):4453-6.
Przewalskin A (1), a novel C23 terpenoid with a 6/6/7 carbon ring skeleton, was isolated from Salvia przewalskii. Its structure was determined by comprehensive 1D NMR, 2D NMR, and MS spectroscopic analysis and subsequently confirmed by a single-crystal X-ray diffraction study of its PDC oxidation derivative (2). Compounds 1 and 2 showed modest anti-HIV-1 activity with EC50 = 41 and 89 microg/mL, respectively.

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