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2006:
Rogers Claude J; Eubanks Lisa M; Dickerson Tobin J; Janda Kim D
Unexpected acetylcholinesterase activity of cocaine esterases.
Journal of the American Chemical Society 2006;
128(
48):.
A series of proteins with cocaine esterase ability have been shown to hydrolyze acetylcholine with similar rate enhancements. Docking studies revealed that acetylcholine binds in a similar orientation as cocaine. These results suggest that acetylcholinesterase activity may be inherent to cocaine esterases.
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