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2007:
Huang Sheng-Xiong; Zhou Yan; Yang Li-Bin; Zhao Yong; Li Sheng-Hong; Lou Li-Guang; Han Quan-Bin; Ding Li-Sheng; Sun Han-Dong
Alboatisins A-C, ent-atisene diterpenoids from Isodon albopilosus.
Journal of natural products 2007;
70(
6):.
Three biogenetically interesting ent-kaurane-derived metabolites, alboatisins A-C (1-3), featuring a C-13-oxygenated ent-atisane skeleton, have been isolated from the aerial parts of Isodon albopilosus. Their structures were determined on the basis of spectroscopic evidence. Compound 2 exhibited cytotoxicity against A549 and HT-29 human cancer cells, with IC50 values of 8.3 and 7.9 microM, respectively.
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