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2007:
Guinane Caitriona M; Cotter Paul D; Lawton Elaine M; Hill Colin; Ross R Paul
Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis.
Applied and environmental microbiology 2007;
73(
14):.
While the potential emergence of food spoilage and pathogenic bacteria with resistance to lantibiotics is a concern, the creation of derivatives of starter cultures and adjuncts that can grow in the presence of these antimicrobials may have applications in food fermentations. Here a bank of Lactococcus lactis IL1403 mutants was created and screened, and a number of novel genetic loci involved in lantibiotic resistance were identified.
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