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2007:
Riedel Christian U; Casey Pat G; Mulcahy Heidi; O'Gara Fergal; Gahan Cormac G M; Hill Colin
Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria.
Applied and environmental microbiology 2007;
73(
21):.
A novel vector has been constructed for the constitutive luminescent tagging of gram-negative bacteria by site-specific integration into the 16S locus of the bacterial chromosome. A number of gram-negative pathogens were successfully tagged using this vector, and the system was validated during murine infections of living animals.
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