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2008:
Mueller Joerg; Skogseid Inger M; Benecke Reiner; Kupsch Andreas; Trottenberg Thomas; Poewe Werner; Schneider Gerd H; Eisner Wilhelm; Wolters Alexander; Müller J U; Deuschl Günther; Pinsker Marcus O; Roeste Geir K; Vollmer-Haase Juliane; Brentrup Angela; Krause Martin; Tronnier Volker; Schnitzler Alfons; Voges Jüergen; Nikkhah Guido; Vesper Jan; Naumann Markus; Volkmann Jens;
Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: results from a prospective, randomized sham-controlled trial.
Movement disorders : official journal of the Movement Disorder Society 2008;
23(
1):.
As part of the first randomized, sham-stimulation controlled trial on deep brain stimulation (DBS) in primary segmental or generalized dystonia, health-related quality of life (HRQoL) was assessed by SF-36. After the 3-month sham-controlled phase, significant HRQoL improvement occurred only in the active-stimulation group. The open-label extension phase resulted in a significant improvement in all SF-36 domains following 6 months of neurostimulation. These results demonstrate a favorable impact of DBS on HRQoL in primary dystonia.
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