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2008:
Baert Leen; Wobus Christiane E; Van Coillie Els; Thackray Larissa B; Debevere Johan; Uyttendaele Mieke
Detection of murine norovirus 1 by using plaque assay, transfection assay, and real-time reverse transcription-PCR before and after heat exposure.
Applied and environmental microbiology 2008;
74(
2):.
The correlation between the detection of murine norovirus 1 RNA by real-time reverse transcription-PCR and the infectivity by plaque assay before and after heat exposure (80 degrees C) was examined. No correlation was found in the current study. Moreover, heat inactivation had a much stronger detrimental effect on virus infectivity than on the integrity of the viral genome.
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