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2008:
Awouafack Maurice D; Kouam Simeon F; Hussain Hidayat; Ngamga Dieudonne; Tane Pierre; Schulz Barbara; Green Ivan R; Krohn Karsten
Antimicrobial prenylated dihydrochalcones from Eriosema glomerata.
Planta medica 2008;
74(
1):.
Two new natural dihydrochalcones exhibiting antimicrobial properties together with six known compounds were isolated from the Cameroonian medicinal plant Eriosema glomerata. The structures of the new dihydrochalcones were elucidated as 2',4'-dihydroxy-4-methoxy-3'-( gamma, gamma-dimethylallyl)dihydrochalcone and 2',4'-dihydroxy-3'-( gamma, gamma-dimethylallyl)dihydrochalcone by detailed spectroscopic analysis. The two new dihydrochalcones, named erioschalcones A ( 1) and B ( 2), demonstrated significant inhibitory activity against the microbial strains Bacillus megaterium, Escherichia coli, Chlorella fusca and Microbotryum violaceum.
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