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2008:
Hudson Michael J; Beyer Wolfgang; Böhm Reinhard; Fasanella Antonio; Garofolo Giuliano; Golinski Robert; Goossens Pierre L; Hahn Ulrike; Hallis Bassam; King Annemarie; Mock Michèle; Montecucco Cesare; Ozin Amanda; Tonello Fiorella; Kaufmann Stefan H E
Bacillus anthracis: balancing innocent research with dual-use potential.
International journal of medical microbiology : IJMM 2008;
298(
5-6):.
Anthrax Euronet, a Coordination Action of the EU 6th Framework Programme, was designed to strengthen networking activities between anthrax research groups in Europe and to harmonise protocols for testing anthrax vaccines and therapeutics. Inevitably, the project also addressed aspects of the current political issues of biosecurity and dual-use research, i.e. research into agents of important diseases of man, livestock or agriculture that could be used as agents of bioterrorism. This review provides a comprehensive overview of the biology of Bacillus anthracis, of the pathogenesis, epidemiology and diagnosis of anthrax, as well as vaccine and therapeutic intervention strategies. The proposed requirement for a code of conduct for working with dual-use agents such as the anthrax bacillus is also discussed.
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