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2008:
Geetha-Loganathan Poongodi; Nimmagadda Suresh; Scaal Martin; Huang Ruijin; Christ Bodo
Wnt signaling in somite development.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2008;
190(
3):.
During vertebrate embryogenesis, specialized mesodermal structures, called somites, give rise to a variety of mesodermal tissues including skeletal muscles, vertebrae and dermis. Development of the somites is a rhythmic process that involves a series of steps including segmentation of the paraxial mesoderm, epithelialization, somite formation, somite maturation, somite patterning and differentiation of somitic cells into different lineages. Wnt signaling has been found to play crucial roles in multiple steps of somite development. In this review, we present a brief overview of current knowledge on Wnt signaling events during the development of somites and their derivatives.
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