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2008:
Capková Katerina; Hixon Mark S; McAllister Laura A; Janda Kim D
Toward the discovery of potent inhibitors of botulinum neurotoxin A: development of a robust LC MS based assay operational from low to subnanomolar enzyme concentrations.
Chemical communications (Cambridge, England) 2008;
(
30):.
The development of a sensitive, yet reliable assay for the analysis of botulinum neurotoxin A (BoNT/A) inhibitors is described; using this assay a new protease inhibitor was characterized and found to be one of the most potent inhibitors reported to date.
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