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2008:
Van Troys Marleen; Lambrechts Anja; David Violaine; Demol Hans; Puype Magda; Pizarro-Cerda Javier; Gevaert Kris; Cossart Pascale; Vandekerckhove Joël
The actin propulsive machinery: the proteome of Listeria monocytogenes tails.
Biochemical and biophysical research communications 2008;
375(
2):.
Actin-based comet tails produced by Listeria monocytogenes are considered as representative models for cellular force-producing machineries crucial for cell migration. We here present a proteomic picture of these tails formed in extracts from brain and platelets. This provides a comprehensive view, revealing high molecular complexity and novel host cell proteins as tail components, and suggests the participation of specific multicomponent regulatory complexes. This work forms a new basis to expand current models of cellular protrusion.
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