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2008:
Xiao Wei-Lie; Huang Sheng-Xiong; Wang Rui-Rui; Zhong Jia-Liang; Gao Xue-Mei; He Fei; Pu Jian-Xin; Lu Yang; Zheng Yong-Tang; Zheng Qi-Tai; Sun Han-Dong
Nortriterpenoids and lignans from Schisandra sphenanthera.
Phytochemistry 2008;
69(
16):.
Nortriterpenoids, sphenadilactone C (1) and sphenasin A (2), together with four known lignans (3-6), were isolated from the leaves and stems of Schisandra sphenanthera. Their structures were elucidated by extensive analysis of 1D and 2D NMR spectroscopic data and compound 2 was further confirmed by single-crystal X-ray diffraction. Compound 1 features a partial enol moiety and an acetamide group in its structure. In addition, compounds 1, 3-6 showed weak anti-HIV-1 activity with EC(50) values in the range of 15.5-29.5 microg/mL.
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