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2009:
Morris Cullen D; Smith Ron D; Kar Biswajit; Ghodsizad Ali; Reverdin Stephane; Frazier O H; Gregoric Igor D
Successful cardiac transplantation in a patient with elevated pulmonary vascular resistance: a relative contraindication to transplantation.
The heart surgery forum 2009;
12(
1):.
Elevated pulmonary vascular resistance in a transplantation candidate should be viewed as potentially reversible, and there are several options for therapy. We describe a young patient with congenital restrictive cardiomyopathy and a markedly elevated pulmonary artery pressure. The patient underwent successful orthotopic heart transplantation after pharmacologic lowering of the pulmonary artery pressure with a new drug combination of milrinone and nesiritide. The length of therapy can be extended to 3 days to allow for determining the pulmonary vascular responsiveness.
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