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2009:
Diercks Tammo; Ribeiro João P; Cañada F Javier; André Sabine; Jiménez-Barbero Jesús; Gabius Hans-Joachim
Fluorinated carbohydrates as lectin ligands: versatile sensors in 19F-detected saturation transfer difference NMR spectroscopy.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;
15(
23):.
As a novel approach for studying carbohydrate-lectin interactions spectroscopically, we combine the resolution and specificity of (19)F-detected NMR spectroscopy with the sensitivity of the saturation transfer difference (STD) technique. The resulting background-free (19)F-STD spectra open a promising perspective for broad application with medical relevance, for example, in drug discovery.
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