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2009:
Matthews Kellie S; Alvarez Ronald D; Curiel David T
Advancements in adenoviral based virotherapy for ovarian cancer.
Advanced drug delivery reviews 2009;
61(
10):.
Ovarian cancer is a leading gynecologic malignancy with relatively grim survival statistics. There is a significant need for the development of new treatment options for this malignancy. The development of virotherapy as a treatment option for ovarian cancer has the potential to improve patient survival. Adenoviruses have multiple advantages as vectors for virotherapy including a well-understood structure and the ability to infect cells easily. We will outline the advances in virotherapy in the treatment of ovarian cancer, with particular attention directed toward adenoviral vectors.
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