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2009:
Zhao Yong; Pu Jian-Xin; Huang Sheng-Xiong; Ding Li-Sheng; Wu Ying-Li; Li Xian; Yang Li-Bin; Xiao Wei-Lie; Chen Guo-Qiang; Sun Han-Dong
ent-Kaurane diterpenoids from Isodon pharicus.
Journal of natural products 2009;
72(
6):.
Phytochemical investigation of the aerial parts of Isodon pharicus led to the isolation of 13 new ent-kaurane diterpenoids, compounds 1-13, together with 12 known analogues (14-25). The structures of the new compounds were determined by means of extensive spectroscopic techniques including interpretation of 1D and 2D NMR spectra. Selected compounds were evaluated for their cytotoxicity against NB4, A549, PC-3, MCF-7, and SH-SY5Y cell lines.
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