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1986:
Maselli R; Jacobsen J H; Spire J P
Edrophonium: an aid in the diagnosis of acute organophosphate poisoning.
Annals of neurology 1986;
19(
5):.
Unsuspected accidental cutaneous exposure to an organophosphate insecticide caused flaccid paralysis in a 10-year-old girl. Electromyogram demonstrated repetitive compound muscle action potentials in response to a single stimulus of nerve; decremental response, more prominent at higher rates of stimulation; worsening of decremental response after edrophonium injection; and normal nerve conduction velocities. Electromyogram with repetitive nerve stimulation and an edrophonium test may provide a simple and rapid method for diagnosis of acute organophosphate poisoning.
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