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Experts in Apolipoprotein E4
A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.
- Saunders, Ann
- Blennow, Kaj
- Soininen, Hilkka
- Mayeux, Richard
- Roses, Allen
- Weisgraber, Karl
- Schellenberg, Gerard
- Mahley, Robert
- Van Broeckhoven, Christine
- Winblad, Bengt
- Small, Gary
- DeKosky, Steven
- Pericak-Vance, Margaret
- Hyman, Bradley
- Lannfelt, Lars
- Mann, D M A
- Nicoll, James
- Helisalmi, Seppo
- Huang, Yadong
- Schmechel, Donald
- Stern, Yaakov
- Haines, Jonathan
- Caselli, Richard
- Combarros, Onofre
- Hardy, John
- Kamboh, Ilyas
- Bennett, David
- Berciano, José
- Martins, Ralph
- Tycko, Benjamin
