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Experts in Perforin
A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.
- Podack, Eckhard
- Trapani, Joseph
- Smyth, Mark
- Yagita, Hideo
- Tschopp, Jürg
- Persechini, Pedro
- Rukavina, Daniel
- Lichtenheld, Mathias
- Hengartner, Hans
- Simon, Markus
- Hudig, Dorothy
- Müllbacher, Arno
- Ojcius, David
- Ortaldo, John
- Strbo, Natasa
- Zinkernagel, Rolf
- Laskarin, Gordana
- Levy, Robert
- Ley, Timothy
- Bleackley, Chris
- Krensky, Alan
- Sasportes, Marilyne
- Sutton, Vivien
- Voskoboinik, Ilia
- Hameed, A
- Harty, John
- Lieberman, Judy
- Mueller, Christoph
- Seko, Yoshinori
- Yasukawa, Masaki
