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Experts in Proto-Oncogene Proteins c-akt
A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
- Alessi, Dario
- Walsh, Kenneth
- Birnbaum, Morris
- Mills, Gordon
- Tsichlis, Philip
- Cheng, Jin
- Hay, Nissim
- Testa, Joseph
- Jiang, Bing-Hua
- Martelli, Alberto
- Dennis, Phillip
- McCubrey, James
- Dent, Paul
- Hung, Mien-Chie
- Woodgett, James
- Coffer, Paul
- Dedhar, Shoukat
- Stokoe, David
- Bellacosa, Alfonso
- Cantley, Lewis
- Chen, Ching-Shih
- Hemmings, Brian
- Saad, Mario
- Ye, Keqiang
- Aggarwal, Bharat
- Grant, Steven
- Kahn, Ronald
- Burgering, Boudewijn
- Evers, Mark
- Hemmings, Brian
