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Experts in Caspase 8
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.
- Krammer, Peter
- Peter, Marcus
- Schulze-Osthoff, Klaus
- Lenardo, Michael
- Salvesen, Guy
- Reed, John
- Tschopp, Jürg
- Yonehara, Shin
- Debatin, Klaus-Michael
- Chaudhary, Preet
- Vandenabeele, Peter
- Belka, Claus
- Cohen, Gerald
- Dixit, Vishva
- Leverkus, Martin
- Scaffidi, C
- Wajant, Harald
- Wesselborg, Sebastian
- Grant, Steven
- Solary, Eric
- Budd, Ralph
- Gupta, Sudhir
- Hakem, Raza
- Jung, Yong-Keun
- Lahti, Jill
- Sakamaki, Kazuhiro
- Schmitz, Ingo
- Sporn, Michael B.
- Weller, Michael
- Billiar, Timothy