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Experts in Botulinum Toxins
Proteins synthesized as a single chain of ~150 kDa with 35% sequence identity to TETANUS TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. They have neuro-, entero-, and hemotoxic properties, are immunogenic, and include the most potent poisons known. The most commonly used apparently blocks release of ACETYLCHOLINE at cholinergic SYNAPSES.
- Aktories, Klaus
- Jankovic, Joseph
- Oguma, Keiji
- Montecucco, Cesare
- Dasgupta, Bibhuti
- Kozaki, Shunji
- Shone, Clifford
- Dolly, Oliver
- Just, Ingo
- Rossetto, Ornella
- Schiavo, Giampietro
- Fujinaga, Yukako
- Popoff, Michel
- Simpson, Lance
- Johnson, Eric
- Bigalke, Hans
- Ohyama, Tohru
- Poulain, Bernard
- Brin, Mitchell
- Dressler, Dirk
- Kamata, Yoichi
- Singh, Bal Ram
- Barth, Holger
- Boquet, Patrice
- Inoue, Kaoru
- Korkeala, Hannu
- Molgó, Jordi
- Yokosawa, Noriko
- Blitzer, Andrew
- Fahn, Stanley
