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Experts in 1-Phosphatidylinositol 3-Kinase
An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. EC 2.7.1.137.
- Cantley, Lewis
- Kahn, Ronald
- Waterfield, Michael
- Vanhaesebroeck, Bart
- Backer, Jonathan
- Ward, Stephen
- Wymann, Matthias
- Mills, Gordon
- Payrastre, Bernard
- Fruman, David
- Hawkins, Phillip
- Downes, Peter
- Van Obberghen, Emmanuel
- Saad, Mario
- Asano, Tomoichiro
- Hirsch, Emilio
- Olefsky, Jerrold
- White, Morris
- Shepherd, Peter
- Klip, Amira
- Vogt, Peter
- Martelli, Alberto
- Blenis, John
- Carrera, Ana
- Downward, Julian
- Gutkind, Silvio
- Hazeki, Osamu
- Jiang, Bing-Hua
- Duronio, Vincent
- Kasuga, Masato
