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Experts in Calpain
Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC 3.4.22.4.
- Banik, Narendra L.
- Shearer, Thomas
- Sorimachi, Hiroyuki
- Melloni, Edon
- Azuma, M
- Saido, Takaomi
- Wang, Kevin
- Ray, Swapan
- Pontremoli, Sandro
- Salamino, Franca
- Baudry, Michel
- Cottin, Patrick
- Goll, Darrel
- Hogan, Edward Leo
- Elce, John
- David, Larry
- Friedrich, Peter
- Hayes, Ronald
- Koohmaraie, Mohammad
- Richard, Isabelle
- Suzuki, Kazutoshi
- Davies, Peter
- Ducastaing, A
- Nixon, Ralph A.
- Poussard, Sylvie
- Fukiage, Chiho
- Ishiura, Shoichi
- Karlsson, Jan-Olof
- Tompa, Peter
- Brustis, Jean-Jacques
