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Experts in PTEN Phosphohydrolase
A lipid phosphatase that acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION.
- Eng, Charis
- Pandolfi, Pier Paolo
- Parsons, Ramon
- Mak, Tak
- Wu, Hong
- Downes, Peter
- Leslie, Nick
- Stokoe, David
- Yung, Alfred
- Mills, Gordon
- Suzuki, Akira
- Cordon-Cardo, Carlos
- Di Cristofano, Antonio
- Sellers, William
- DePinho, Ronald
- Koul, Dimpy
- Marsh, Deborah
- Waite, Kristin
- Sasaki, Takehiko
- Zhou, Xiao-Ping
- Abate-Shen, Cory
- Baker, Suzanne
- Devreotes, Peter
- Dixon, Jack
- Mak, Tak Wah
- Sawyers, Charles
- Stambolic, Vuk
- Ellenson, Lora Hedrick
- Horie, Yasuo
- Liu, Xin
