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Experts in Debrisoquin
An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
- Bertilsson, Leif
- Dahl, Marja-Liisa
- LLerena, Adrián
- Benitez, Julio
- Meyer, Urs
- Lennard, Martin
- Tucker, Geoffrey
- Branch, Robert
- Idle, Jeffrey
- Ingelman-Sundberg, Magnus
- Johansson, Inger
- Sjöqvist, Folke
- Brøsen, Kim
- Wilkinson, Grant
- Eichelbaum, Michel
- Alm, C
- Frye, Reginald
- Gonzalez, Frank
- Ladero, José
- Säwe, Juliette
- Wood, Alastair
- Dalén, Per
- Daly, Ann
- Dorado, Pedro
- Kallio, Jaana
- Spina, Edoardo
- Svensson, Jan-Olof
- Bechtel, PR
- Berecz, Roland
- Bozkurt, Atila