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Kenji Nakano

Research Profile

Disorders

Procedures

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Physiology

Liver Regeneration

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Y-Box-Binding Protein 1

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Masahiro Ohgidani; Kentaro Shinkai; Koichi Furugaki; Keiji Itaka; Kazunori Kataoka; Yumi Kunisawa; Kenji Nakano
Block/homo polyplex micelle-based GM-CSF gene therapy via intraperitoneal administration elicits antitumor immunity against peritoneal dissemination and exhibits safety potentials in mice and cynomolgus monkeys.
Seiichi Odate; Hideya Onishi; Masao Tanaka; Akihiko Uchiyama; Masato Kato; Masayuki Kojima; Katsuya Nakamura; Kenji Nakano; Mitsuo Katano
TrkB/BDNF signaling pathway is a potential therapeutic target for pulmonary large cell neuroendocrine carcinoma.
Hironori Iwasaki; Minako Hirahashi; Yumi Kunisawa; Kenji Nakano; Yoshinao Oda; Hideya Onishi; Kentaro Shinkai; Mitsuo Katano
Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherence-related genes.

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2013: Masahiro Ohgidani; Kentaro Shinkai; Koichi Furugaki; Keiji Itaka; Kazunori Kataoka; Yumi Kunisawa; Kenji Nakano
Block/homo polyplex micelle-based GM-CSF gene therapy via intraperitoneal administration elicits antitumor immunity against peritoneal dissemination and exhibits safety potentials in mice and cynomolgus monkeys.
Journal of controlled release : official journal of the Controlled Release Society 2013;167(3):238-47.
2013: Seiichi Odate; Hideya Onishi; Masao Tanaka; Akihiko Uchiyama; Masato Kato; Masayuki Kojima; Katsuya Nakamura; Kenji Nakano; Mitsuo Katano
TrkB/BDNF signaling pathway is a potential therapeutic target for pulmonary large cell neuroendocrine carcinoma.
Lung cancer (Amsterdam, Netherlands) 2013;79(3):205-14.
2013: Hironori Iwasaki; Minako Hirahashi; Yumi Kunisawa; Kenji Nakano; Yoshinao Oda; Hideya Onishi; Kentaro Shinkai; Mitsuo Katano
Hedgehog Gli3 activator signal augments tumorigenicity of colorectal cancer via upregulation of adherence-related genes.
Cancer science 2013;104(3):328-36.
2013: Hiroaki Uchida; Ji Young Yoo; Hyunjung Baek; Janet Chan; E Antonio Chiocca; Justus B Cohen; William F Goins; Paola Grandi; Amy Haseley; Chang-Sook Hong; Balveen Kaur; Izumi Kumagai; Masahide Kuroki; Heechung Kwon; Marco Marzulli; Lucia Mazzacurati; Kenji Nakano; Hiroshi Nakashima; Joseph C Glorioso
Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(3):561-9.
2012: Michiaki Kumagai; Yumi Kunisawa; Takehiko Ishii; Keiji Itaka; Kazunori Kataoka; Nobuhiro Nishiyama; Kensuke Osada; Shinya Shimoda; Rie Wakabayashi; Kenji Nakano
Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination.
Journal of controlled release : official journal of the Controlled Release Society 2012;160(3):542-51.
2011: Gang Zhao; Yumi Fukunaga; Michiaki Kumagai; Shinya Shimoda; Masao Tanaka; Rie Wakabayashi; Kenji Nakano
Impaired activities of cyclic adenosine monophosphate-responsive element binding protein, protein kinase A and calcium-independent phospholipase A2 are involved in deteriorated regeneration of cirrhotic liver after partial hepatectomy in rats.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(11):1110-9.
2011: Yoshiki Kitaura; Kenji Nakano; Hideya Onishi; Masao Tanaka; Takehiko Tasaka; Nobuhito Chikazawa; Mitsuo Katano
Transforming growth factor β1 contributes to the invasiveness of pancreatic ductal adenocarcinoma cells through the regulation of CD24 expression.
Pancreas 2011;40(7):1034-42.
2011: Rui Xu; Kenji Nakano; Hironori Iwasaki; Michiaki Kumagai; Rie Wakabayashi; Akio Yamasaki; Hiroyuki Suzuki; Ryuichi Mibu; Hideya Onishi; Mitsuo Katano
Dual blockade of phosphatidylinositol 3'-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer.
Cancer letters 2011;306(2):151-60.
2011: Kenji Nakano; Masatoshi Kobayashi; Kei-Ichiro Nakamura; Takeshi Nakanishi; Ryutaro Asano; Izumi Kumagai; Hideaki Tahara; Michihiko Kuwano; Justus B Cohen; Joseph C Glorioso
Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor.
Virology 2011;413(1):12-8.
2010: Yuji Basaki; Ken-Ichi Taguchi; Hiroto Izumi; Yuichi Murakami; Takuya Kubo; Fumihito Hosoi; Kosuke Watari; Kenji Nakano; Hidetoshi Kawaguchi; Shinji Ohno; Kimitoshi Kohno; Mayumi Ono; Michihiko Kuwano
Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells.
European journal of cancer (Oxford, England : 1990) 2010;46(5):954-65.
2010: Hiroyuki Suzuki; Hideya Onishi; Junji Wada; Akio Yamasaki; Haruo Tanaka; Kenji Nakano; Takashi Morisaki; Mitsuo Katano
VEGFR2 is selectively expressed by FOXP3high CD4+ Treg.
European journal of immunology 2010;40(1):197-203.
2009: Masaki Kashihara; Koichi Azuma; Akihiko Kawahara; Yuji Basaki; Satoshi Hattori; Takashi Yanagawa; Yasuhiro Terazaki; Shinzo Takamori; Kazuo Shirouzu; Hisamichi Aizawa; Kenji Nakano; Masayoshi Kage; Michihiko Kuwano; Mayumi Ono
Nuclear Y-box binding protein-1, a predictive marker of prognosis, is correlated with expression of HER2/ErbB2 and HER3/ErbB3 in non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009;4(9):1066-74.
2005: Koji Yamaguchi; Kiichiro Kobayashi; Yasuhiro Ogura; Katsumasa Nakamura; Kenji Nakano; Kazuhiro Mizumoto; Masao Tanaka
Radiation therapy, bypass operation and celiac plexus block in patients with unresectable locally advanced pancreatic cancer.
Hepato-gastroenterology 2005;52(65):1605-12.
2005: Koji Yamaguchi; Hiroyuki Konomi; Kiichiro Kobayashi; Yasuhiro Ogura; Yukio Sonoda; Masahiko Kawamoto; Kenji Nakano; Masao Tanaka
Total pancreatectomy for intraductal papillary-mucinous tumor of the pancreas: reappraisal of total pancreatectomy.
Hepato-gastroenterology 2005;52(65):1585-90.
2005: Koji Yamaguchi; Katsumasa Nakamura; Kiichiro Kobayashi; Kenji Nakano; Hiroyuki Konomi; Kazuhiro Mizumoto; Masao Tanaka
ERT following IORT improves survival of patients with resectable pancreatic cancer.
Hepato-gastroenterology 2005;52(64):1244-9.
2005: Koji Yamaguchi; Kenji Nakano; Eishi Nagai; Kazuo Chijiiwa; Moritoshi Kinoshita; Masayuki Ohta; Masao Tanaka
Ki-ras mutations in codon 12 and p53 mutations (biomarkers) and cytology in bile in patients with hepatobiliary-pancreatic carcinoma.
Hepato-gastroenterology 2005;52(63):713-8.
2005: Kenji Nakano; Tomoki Todo; Gang Zhao; Koji Yamaguchi; Syoji Kuroki; Justus B Cohen; Joseph C Glorioso; Masao Tanaka
Enhanced efficacy of conditionally replicating herpes simplex virus (G207) combined with 5-fluorouracil and surgical resection in peritoneal cancer dissemination models.
The journal of gene medicine 2005;7(5):638-48.
2004: Masayuki Kojima; Takashi Morisaki; Nobuhiko Sasaki; Kenji Nakano; Ryuichi Mibu; Masao Tanaka; Mitsuo Katano
Increased nuclear factor-kB activation in human colorectal carcinoma and its correlation with tumor progression.
Anticancer research 2004;24(2B):675-81.
2004: Chizu Furuhira; Akira Ohshima; Kazuo Shimada; Syoji Kuroki; Kenji Nakano; Mikimasa Ishikawa; Hidetaka Yamamoto; Masao Tanaka
A case of breast cholesterol granuloma accompanied by cancer.
Breast cancer (Tokyo, Japan) 2004;11(2):210-3.
2003: Takayuki Toyonaga; Kenji Nakano; Masahiro Nagano; Gang Zhao; Koji Yamaguchi; Syoji Kuroki; Takashi Eguchi; Kazuo Chijiiwa; Masazumi Tsuneyoshi; Masao Tanaka
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
Cancer letters 2003;201(1):107-16.
2003: Kenji Nakano; Kazuo Chijiiwa; Takayuki Toyonaga; Junji Ueda; Yuji Takamatsu; Masahiko Kimura; Katsumasa Nakamura; Koji Yamaguchi; Masao Tanaka
Combination therapy of resection and intraoperative radiation for patients with carcinomas of extrahepatic bile duct and ampulla of Vater: prognostic advantage over resection alone?
Hepato-gastroenterology 2003;50(52):928-33.
2003: Kenji Nakano; Atsushi Mizuta; Seiji Oohashi; Syoji Kuroki; Koji Yamaguchi; Masao Tanaka; Kiyoshi Zaitsu
Protein stone formation in an intrapancreatic remnant cyst after resection of a choledochal cyst.
Pancreas 2003;26(4):405-7.
2003: Takayuki Toyonaga; Kazuo Chijiiwa; Kenji Nakano; Hirokazu Noshiro; Koji Yamaguchi; Masayuki Sada; Reiji Terasaka; Kohki Konomi; Fujihiko Nishikata; Masao Tanaka
Completion radical surgery after cholecystectomy for accidentally undiagnosed gallbladder carcinoma.
World journal of surgery 2003;27(3):266-71.
2003: Koji Yamaguchi; Kenji Nakano; Kiichiro Kobayashi; Yasuhiro Ogura; Hiroyuki Konomi; Atsushi Sugitani; Masao Tanaka
Appleby operation for pancreatic body-tail carcinoma: report of three cases.
Surgery today 2003;33(11):873-8.
2002: Junji Ueda; Kazuo Chijiiwa; Kenji Nakano; Gang Zhao; Masao Tanaka
Lack of intestinal bile results in delayed liver regeneration of normal rat liver after hepatectomy accompanied by impaired cyclin E-associated kinase activity.
Surgery 2002;131(5):564-73.
2002: Gang Zhao; Kenji Nakano; Kazuo Chijiiwa; Junji Ueda; Masao Tanaka
Inhibited activities in CCAAT/enhancer-binding protein, activating protein-1 and cyclins after hepatectomy in rats with thioacetamide-induced liver cirrhosis.
Biochemical and biophysical research communications 2002;292(2):474-81.
2002: Koji Yamaguchi; Jiro Ohuchida; Takao Ohtsuka; Kenji Nakano; Masao Tanaka
Intraductal papillary-mucinous tumor of the pancreas concomitant with ductal carcinoma of the pancreas.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2002;2(5):484-90.
2002: Masato Watanabe; Kazuo Chijiiwa; Nobuhisa Kameoka; Kenji Nakano; Hirokazu Noshiro; Masao Tanaka
Effects of streptococcal preparation OK-432 on liver regeneration and energy status after partial hepatectomy under ischemia/reperfusion in rats.
Hepato-gastroenterology 2002;49(43):218-21.
2001: Koji Yamaguchi; M Kishinaka; Eishi Nagai; Kenji Nakano; Takao Ohtsuka; K Chijiwa; Masao Tanaka
Pancreatoduodenectomy for pancreatic head carcinoma with or without pylorus preservation.
Hepato-gastroenterology 2001;48(41):1479-85.
2001: Koji Yamaguchi; Hirokazu Noshiro; Kazunori Yokohata; Kenji Nakano; M Watanabe; K Ohtani; Kazuo Chijiiwa; Masao Tanaka
Is there any benefit of preservation of the spleen in distal pancreatectomy?
International surgery 2001;86(3):162-8.
2001: Kazuo Chijiiwa; Kenji Nakano; Junji Ueda; Hirokazu Noshiro; Eishi Nagai; Koji Yamaguchi; Masao Tanaka
Surgical treatment of patients with T2 gallbladder carcinoma invading the subserosal layer.
Journal of the American College of Surgeons 2001;192(5):600-7.
2001: Kenji Nakano; T Todo; Kazuo Chijiiwa; Masao Tanaka
Therapeutic efficacy of G207, a conditionally replicating herpes simplex virus type 1 mutant, for gallbladder carcinoma in immunocompetent hamsters.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(4):431-7.
2001: Koji Yamaguchi; Kazunori Yokohata; Kenji Nakano; K Ohtani; Yoshiaki Ogawa; Kazuo Chijiiwa; Masao Tanaka
Which is a less invasive pancreatic head resection: PD, PPPD, or DPPHR?
Digestive diseases and sciences 2001;46(2):282-8.
2001: Kenji Nakano; Kazuo Chijiiwa; Masao Tanaka
Lower activity of CCAAT/enhancer-binding protein and expression of cyclin E, but not cyclin D1, activating protein-1 and p21(WAF1), after partial hepatectomy in obstructive jaundice.
Biochemical and biophysical research communications 2001;280(3):640-5.
2000: Kazuo Chijiiwa; Hirokazu Noshiro; Kenji Nakano; Masayuki Okido; Atsushi Sugitani; Koji Yamaguchi; Masao Tanaka
Role of surgery for gallbladder carcinoma with special reference to lymph node metastasis and stage using western and Japanese classification systems.
World journal of surgery 2000;24(10):1271-6; discussion 1277.
2000: Kazuo Chijiiwa; S Saiki; Hirokazu Noshiro; Nobuhisa Kameoka; Kenji Nakano; Masao Tanaka
Effect of preoperative portal vein embolization on liver volume and hepatic energy status of the nonembolized liver lobe in humans.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2000;32(2):94-9.