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Harshal Nandurkar

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M Nikpour; D Prior; Susanna M Proudman; W Stevens; T Williams; J Zochling; Rachelle Buchbinder; Eli Gabbay; Harshal H Nandurkar
Should patients with systemic sclerosis-related pulmonary arterial hypertension be anticoagulated?
Jan David Hohmann; Stefanie Krajewski; Harshal H Nandurkar; Elliot L Chaikof; Christoph Hagemeyer; Carolyn A Haller; Carly Selan; Andreas Straub; Xiaowei Wang; Karlheinz Peter
Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?
X L Tan; R Mckellar; Harshal H Nandurkar; C Tam; A Bazargan
Out of sight, out of mind: an audit of inferior vena cava filter insertion and clinical follow up in an Australian institution and literature review.

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All Publications

2013: M Nikpour; D Prior; Susanna M Proudman; W Stevens; T Williams; J Zochling; Rachelle Buchbinder; Eli Gabbay; Harshal H Nandurkar
Should patients with systemic sclerosis-related pulmonary arterial hypertension be anticoagulated?
Internal medicine journal 2013;43(5):599-603.
2013: Jan David Hohmann; Stefanie Krajewski; Harshal H Nandurkar; Elliot L Chaikof; Christoph Hagemeyer; Carolyn A Haller; Carly Selan; Andreas Straub; Xiaowei Wang; Karlheinz Peter
Delayed targeting of CD39 to activated platelet GPIIb/IIIa via a single-chain antibody: breaking the link between antithrombotic potency and bleeding?
Blood 2013;121(16):3067-75.
2013: X L Tan; R Mckellar; Harshal H Nandurkar; C Tam; A Bazargan
Out of sight, out of mind: an audit of inferior vena cava filter insertion and clinical follow up in an Australian institution and literature review.
Internal medicine journal 2013;43(4):365-72.
2012: Ruth N MacKinnon; Harshal H Nandurkar; Carly Selan; Meaghan Wall; Adrian Zordan; Lynda J Campbell
CGH and SNP array using DNA extracted from fixed cytogenetic preparations and long-term refrigerated bone marrow specimens.
Molecular cytogenetics 2012;5():10.
2010: Sandra Crikis; B Lu; L M Murray-Segal; C Selan; Simon C Robson; A J F D'Apice; Harshal H Nandurkar; Peter J Cowan; Karen M Dwyer
Transgenic overexpression of CD39 protects against renal ischemia-reperfusion and transplant vascular injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010;10(12):2586-95.
2010: Monica J Naughtin; David A Sheffield; Parvin Rahman; William E Hughes; Rajendra Gurung; Jennifer L Stow; Harshal H Nandurkar; Jennifer M Dyson; Christina A Mitchell
The myotubularin phosphatase MTMR4 regulates sorting from early endosomes.
Journal of cell science 2010;123(Pt 18):3071-83.
2010: Sandra Crikis; X M Zhang; S Dezfouli; Karen M Dwyer; L M Murray-Segal; Evelyn Salvaris; C Selan; Simon C Robson; Harshal H Nandurkar; Peter J Cowan; Anthony J F d'Apice
Anti-inflammatory and anticoagulant effects of transgenic expression of human thrombomodulin in mice.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010;10(2):242-50.
2008: Gregory T C Moore; Steven J Brown; Adam C Winterhalter; Mark Lust; Evelyn Salvaris; Carly Selan; Harshal H Nandurkar; Paul V Desmond; Peter J Cowan; Anthony J F d'Apice
Glycosylation changes in hFUT1 transgenic mice increase TCR signaling and apoptosis resulting in thymocyte maturation arrest.
Molecular immunology 2008;45(8):2401-10.
2007: Yi Xiao; Joel Yeong Chit Chia; Joanna E Gajewski; Daisy Sio Seng Lio; Terrence D Mulhern; Hong-Jian Zhu; Harshal H Nandurkar; Heung-Chin Cheng
PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid--mechanistic analysis of a familial Cowden disease-associated PTEN mutation.
Cellular signalling 2007;19(7):1434-45.
2006: Warren S Alexander; Elizabeth M Viney; Jian-Guo Zhang; Donald Metcalf; Maria Kauppi; Craig D Hyland; Marina R Carpinelli; William Stevenson; Ben A Croker; Adrienne A Hilton; Sarah Ellis; Carly Selan; Harshal H Nandurkar; Christopher C Goodnow; Benjamin T Kile; Nicos A Nicola; Andrew W Roberts; Douglas J Hilton
Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16442-7.
2006: Karen M Dwyer; Tharun B Mysore; Harshal H Nandurkar; Simon C Robson; Peter J Cowan; Sandra Crikis; Anthony J F d'Apice
The transgenic expression of human CD39 on murine islets inhibits clotting of human blood.
Transplantation 2006;82(3):428-32.
2006: Anne M Kong; Kristy A Horan; Absorn Sriratana; Charles G Bailey; Luke J Collyer; Harshal H Nandurkar; Assia Shisheva; Meredith J Layton; John Rasko; Tony Rowe; Christina A Mitchell
Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.
Molecular and cellular biology 2006;26(16):6065-81.
2006: Kenneth Opeskin; Harsha Sheorey; Gavin Wright; Harshal H Nandurkar
Favourable outcome of pulmonary zygomycosis in haematological malignancy.
Pathology 2006;38(3):271-3.
2006: Andrew Boyle; Robert Whitbourn; Stephen Schlicht; Henry Krum; Alfred Kocher; Harshal H Nandurkar; Steven Bergmann; Mark Daniell; Justin O'Day; Donna Skerrett; David Haylock; Richard E Gilbert; Silviu Itescu
Intra-coronary high-dose CD34+ stem cells in patients with chronic ischemic heart disease: a 12-month follow-up.
International journal of cardiology 2006;109(1):21-7.
2006: Lisa M Ooms; Clare G Fedele; Megan V Astle; Ivan Ivetac; Vanessa Cheung; Richard B Pearson; Meredith J Layton; Ariel Forrai; Harshal H Nandurkar; Christina A Mitchell
The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.
Molecular biology of the cell 2006;17(2):607-22.
2004: E Bertini; Valérie Biancalana; Alessandra Bolino; Anna Buj-Bello; M Clague; Pascale Guicheney; Heinz Jungbluth; Wolfram Kress; A Musaro'; Harshal H Nandurkar; Luciano Pirola; Norma B Romero; J Senderek; U Suter; Caroline Sewry; H Tronchere; Carina Wallgren-Pettersson; Matthew J Wishart; Jocelyn Laporte
118th ENMC International Workshop on Advances in Myotubular Myopathy. 26-28 September 2003, Naarden, The Netherlands. (5th Workshop of the International Consortium on Myotubular Myopathy).
Neuromuscular disorders : NMD 2004;14(6):387-96.
2004: Karen M Dwyer; Simon C Robson; Harshal H Nandurkar; Duncan J Campbell; Hilton Gock; Lisa Murray-Segal; Nella Fisicaro; Tharun B Mysore; Elzbieta Kaczmarek; Peter J Cowan; Anthony J F d'Apice
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation.
The Journal of clinical investigation 2004;113(10):1440-6.
2004: Katrina L Scarff; Kheng Ung; Harshal H Nandurkar; Peter J Crack; Catherina H Bird; Phillip I Bird
Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke.
Molecular and cellular biology 2004;24(9):4075-82.
2003: Kenneth Opeskin; Michael Burke; Gerrard McCaffrey; Harshal H Nandurkar
Hodgkin's disease associated cholestasis in a man with thymoma.
Pathology 2003;35(4):349-51.
2003: Jennifer M Dyson; Adam D Munday; Anne M Kong; Richard D Huysmans; Maria Matzaris; Meredith J Layton; Harshal H Nandurkar; Michael C Berndt; Christina A Mitchell
SHIP-2 forms a tetrameric complex with filamin, actin, and GPIb-IX-V: localization of SHIP-2 to the activated platelet actin cytoskeleton.
Blood 2003;102(3):940-8.
2003: Harshal H Nandurkar; Meredith Layton; Jocelyn Laporte; Carly Selan; Lisa Corcoran; Kevin K Caldwell; Yasuhiro Mochizuki; Philip W Majerus; Christina A Mitchell
Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8660-5.
2003: Imogen D Coghill; Susan Brown; Denny Luke Cottle; Meagan J McGrath; Paul A Robinson; Harshal H Nandurkar; Jennifer M Dyson; Christina A Mitchell
FHL3 is an actin-binding protein that regulates alpha-actinin-mediated actin bundling: FHL3 localizes to actin stress fibers and enhances cell spreading and stress fiber disassembly.
The Journal of biological chemistry 2003;278(26):24139-52.
2002: Harshal H Nandurkar; Richard Huysmans
The myotubularin family: novel phosphoinositide regulators.
IUBMB life 2002;53(1):37-43.
2001: Jennifer M Dyson; CJ O'Malley; J Becanovic; Adam D Munday; Michael C Berndt; Imogen D Coghill; Harshal H Nandurkar; Lisa M Ooms; Christina A Mitchell
The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.
The Journal of cell biology 2001;155(6):1065-79.
2001: Harshal H Nandurkar; Kevin K Caldwell; James C Whisstock; Meredith J Layton; EA Gaudet; FA Norris; Philip W Majerus; Christina A Mitchell
Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9499-504.
2001: Clare L Scott; Lorraine Robb; Harshal H Nandurkar; R Mansfield; Warren S Alexander; C Glenn Begley
Thrombopoietin signaling is required for in vivo expansion of IL-11--responsive hematopoietic progenitor cells in the steady state.
Experimental hematology 2001;29(2):138-45.
2000: James C Whisstock; S Romero; Rajendra Gurung; Harshal H Nandurkar; Lisa M Ooms; Stephen P Bottomley; Christina A Mitchell
The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis.
The Journal of biological chemistry 2000;275(47):37055-61.
2000: T Gainsford; Harshal H Nandurkar; Donald Metcalf; Lorraine Robb; C Glenn Begley; Warren S Alexander
The residual megakaryocyte and platelet production in c-mpl-deficient mice is not dependent on the actions of interleukin-6, interleukin-11, or leukemia inhibitory factor.
Blood 2000;95(2):528-34.
1998: Lorraine Robb; R Li; L Hartley; Harshal H Nandurkar; Frank Koentgen; C Glenn Begley
Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation.
Nature medicine 1998;4(3):303-8.
1998: Harshal H Nandurkar; Lorraine Robb; C Glenn Begley
The role of IL-II in hematopoiesis as revealed by a targeted mutation of its receptor.
Stem cells (Dayton, Ohio) 1998;16 Suppl 2():53-65.
1997: Harshal H Nandurkar; Lorraine Robb; David M Tarlinton; Louise Barnett; F Köntgen; C Glenn Begley
Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis.
Blood 1997;90(6):2148-59.
1997: Harshal H Nandurkar; Lorraine Robb; J K Nicholl; Douglas J Hilton; G R Sutherland; C Glenn Begley
The gene for the human interleukin-11 receptor alpha chain locus is highly homologous to the murine gene and contains alternatively spliced first exons.
The international journal of biochemistry & cell biology 1997;29(5):753-66.
1996: Harshal H Nandurkar; Douglas J Hilton; P Nathan; Tracy A Willson; Nicos A Nicola; C Glenn Begley
The human IL-11 receptor requires gp130 for signalling: demonstration by molecular cloning of the receptor.
Oncogene 1996;12(3):585-93.