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Elizabeth Nardin

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TOP 3
Elizabeth H Nardin
The past decade in malaria synthetic peptide vaccine clinical trials.
Caroline Othoro; Dean Johnston; Rebecca Lee; Jonathan Soverow; Jean-Claude Bystryn; Elizabeth H Nardin
Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod.
Ute Frevert; Elizabeth H Nardin
Cellular effector mechanisms against Plasmodium liver stages.

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All Publications

2010: Elizabeth H Nardin
The past decade in malaria synthetic peptide vaccine clinical trials.
Human vaccines 2010;6(1):27-38.
2009: Caroline Othoro; Dean Johnston; Rebecca Lee; Jonathan Soverow; Jean-Claude Bystryn; Elizabeth H Nardin
Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod.
Infection and immunity 2009;77(2):739-48.
2008: Ute Frevert; Elizabeth H Nardin
Cellular effector mechanisms against Plasmodium liver stages.
Cellular microbiology 2008;10(10):1956-67.
2008: Giane A Oliveira; Kota Arun Kumar; J Mauricio Calvo-Calle; Caroline Othoro; David Altszuler; Victor Nussenzweig; Elizabeth H Nardin
Class II-restricted protective immunity induced by malaria sporozoites.
Infection and immunity 2008;76(3):1200-6.
2008: Aric Gregson; Giane Oliveira; Caroline Othoro; J Mauricio Calvo-Calle; george thornton; Elizabeth H Nardin; Robert Edelman
Phase I trial of an alhydrogel adjuvanted hepatitis B core virus-like particle containing epitopes of Plasmodium falciparum circumsporozoite protein.
PloS one 2008;3(2):e1556.
2006: J Mauricio Calvo-Calle; Giane A Oliveira; Carol Othoro Watta; Jonathan Soverow; Carlos Parra-Lopez; Elizabeth H Nardin
A linear peptide containing minimal T- and B-cell epitopes of Plasmodium falciparum circumsporozoite protein elicits protection against transgenic sporozoite challenge.
Infection and immunity 2006;74(12):6929-39.
2006: Carlos Parra-López; J Mauricio Calvo-Calle; Thomas O Cameron; Luis Eduardo Vargas; Luz Mary Salazar; Manuel E Patarroyo; Elizabeth H Nardin; Lawrence J Stern
Major histocompatibility complex and T cell interactions of a universal T cell epitope from Plasmodium falciparum circumsporozoite protein.
The Journal of biological chemistry 2006;281(21):14907-17.
2005: J Mauricio Calvo-Calle; Giane A Oliveira; Elizabeth H Nardin
Human CD4+ T cells induced by synthetic peptide malaria vaccine are comparable to cells elicited by attenuated Plasmodium falciparum sporozoites.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7575-85.
2005: Jan A M Langermans; Annette Schmidt; Richard Vervenne; Ashley Birkett; J Mauricio Calvo-Calle; Meike Hensmann; george thornton; Filip Dubovsky; Horst Weiler; Elizabeth H Nardin; Alan Thomas
Effect of adjuvant on reactogenicity and long-term immunogenicity of the malaria Vaccine ICC-1132 in macaques.
Vaccine 2005;23(41):4935-43.
2005: Giane A Oliveira; Kristiane Wetzel; J Mauricio Calvo-Calle; Ruth S Nussenzweig; Annette Schmidt; Ashley Birkett; Filip Dubovsky; Eveline Tierney; Christoph H Gleiter; Gabriele Boehmer; Adrian J F Luty; Michael Ramharter; george thornton; Song Le; Elizabeth H Nardin
Safety and enhanced immunogenicity of a hepatitis B core particle Plasmodium falciparum malaria vaccine formulated in adjuvant Montanide ISA 720 in a phase I trial.
Infection and immunity 2005;73(6):3587-97.
2005: Ute Frevert; Elizabeth H Nardin
Arrest in the liver--a genetically defined malaria vaccine?
The New England journal of medicine 2005;352(15):1600-2.
2004: Elizabeth H Nardin; Giane A Oliveira; J Mauricio Calvo-Calle; Kristiane Wetzel; Carolin Maier; Ashley Birkett; Pramod Sarpotdar; Michael L Corado; george thornton; Annette Schmidt
Phase I testing of a malaria vaccine composed of hepatitis B virus core particles expressing Plasmodium falciparum circumsporozoite epitopes.
Infection and immunity 2004;72(11):6519-27.
2004: Kota Arun Kumar; Giane A Oliveira; Robert Edelman; Elizabeth H Nardin; Victor Nussenzweig
Quantitative Plasmodium sporozoite neutralization assay (TSNA).
Journal of immunological methods 2004;292(1-2):157-64.
2002: Cathrine Persson; Giane A Oliveira; Ali A Sultan; Purnima Bhanot; Victor Nussenzweig; Elizabeth H Nardin
Cutting edge: a new tool to evaluate human pre-erythrocytic malaria vaccines: rodent parasites bearing a hybrid Plasmodium falciparum circumsporozoite protein.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(12):6681-5.
2002: Robert Edelman; Steven Wasserman; James Kublin; Sacared A Bodison; Elizabeth H Nardin; Giane A Oliveira; Sobia Ansari; Carter L Diggs; Oscar L Kashala; Barbara J Schmeckpeper; Robert G Hamilton
Immediate-type hypersensitivity and other clinical reactions in volunteers immunized with a synthetic multi-antigen peptide vaccine (PfCS-MAP1NYU) against Plasmodium falciparum sporozoites.
Vaccine 2002;21(3-4):269-80.
2002: Ashley Birkett; K Lyons; Annette Schmidt; D Boyd; Giane A Oliveira; A Siddique; Ruth S Nussenzweig; J Mauricio Calvo-Calle; Elizabeth H Nardin
A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts.
Infection and immunity 2002;70(12):6860-70.
2002: James Kublin; Mark H Lowitt; Robert G Hamilton; Giane A Oliveira; Elizabeth H Nardin; Ruth S Nussenzweig; Barbara J Schmeckpeper; Carter L Diggs; Sacared A Bodison; Robert Edelman
Delayed-type hypersensitivity in volunteers immunized with a synthetic multi-antigen peptide vaccine (PfCS-MAP1NYU) against Plasmodium falciparum sporozoites.
Vaccine 2002;20(13-14):1853-61.
2002: Photini Sinnis; Elizabeth H Nardin
Sporozoite antigens: biology and immunology of the circumsporozoite protein and thrombospondin-related anonymous protein.
Chemical immunology 2002;80():70-96.
2001: Elizabeth H Nardin; J Mauricio Calvo-Calle; Giane A Oliveira; Ruth S Nussenzweig; M Schneider; J M Tiercy; L Loutan; D Hochstrasser; K Rose
A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):481-9.
2000: Elizabeth H Nardin; Giane A Oliveira; J Mauricio Calvo-Calle; Z R Castro; Ruth S Nussenzweig; Barbara J Schmeckpeper; Beverly Hall; Carter L Diggs; Sacared A Bodison; Robert Edelman
Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes.
The Journal of infectious diseases 2000;182(5):1486-96.
1999: Elizabeth H Nardin; Fidel Zavala; Victor Nussenzweig; Ruth S Nussenzweig
Pre-erythrocytic malaria vaccine: mechanisms of protective immunity and human vaccine trials.
Parassitologia 1999;41(1-3):397-402.
1999: C A Moreno; R Rodriguez; Giane A Oliveira; Viviana Ferreira; Ruth S Nussenzweig; Z R Moya Castro; J Mauricio Calvo-Calle; Elizabeth H Nardin
Preclinical evaluation of a synthetic Plasmodium falciparum MAP malaria vaccine in Aotus monkeys and mice.
Vaccine 1999;18(1-2):89-99.
1998: Elizabeth H Nardin; J Mauricio Calvo-Calle; Giane A Oliveira; P Clavijo; Ruth S Nussenzweig; R Simon; W Zeng; K Rose
Plasmodium falciparum polyoximes: highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS protein.
Vaccine 1998;16(6):590-600.
1997: J Mauricio Calvo-Calle; J Hammer; F Sinigaglia; P Clavijo; Z R Moya-Castro; Elizabeth H Nardin
Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: identification of a universal T cell epitope in the Plasmodium falciparum circumsporozoite protein.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(3):1362-73.
1995: Elizabeth H Nardin; Giane A Oliveira; J Mauricio Calvo-Calle; Ruth S Nussenzweig
The use of multiple antigen peptides in the analysis and induction of protective immune responses against infectious diseases.
Advances in immunology 1995;60():105-49.
1994: J Mauricio Calvo-Calle; Alberto Moreno; W M Eling; Elizabeth H Nardin
In vitro development of infectious liver stages of P. yoelii and P. berghei malaria in human cell lines.
Experimental parasitology 1994;79(3):362-73.
1994: G A de Oliveira; P Clavijo; Ruth S Nussenzweig; Elizabeth H Nardin
Immunogenicity of an alum-adsorbed synthetic multiple-antigen peptide based on B- and T-cell epitopes of the Plasmodium falciparum CS protein: possible vaccine application.
Vaccine 1994;12(11):1012-7.
1994: C Gonzalez; David Hone; FR Noriega; Carol O Tacket; J R Davis; Genevieve A Losonsky; James P Nataro; S Hoffman; A Malik; Elizabeth H Nardin; Marcelo B Sztein; D G Heppner; T R Fouts; A Isibasi; Myron M Levine
Salmonella typhi vaccine strain CVD 908 expressing the circumsporozoite protein of Plasmodium falciparum: strain construction and safety and immunogenicity in humans.
The Journal of infectious diseases 1994;169(4):927-31.
1993: Maria Stela Branquinho; C B Lagos; R M Rocha; Delsio Natal; José Maria Soares Barata; A H Cochrane; Elizabeth H Nardin; Ruth S Nussenzweig; Judith K Kloetzel
Anophelines in the state of Acre, Brazil, infected with Plasmodium falciparum, P. vivax, the variant P. vivax VK247 and P. malariae.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(4):391-4.
1993: Alberto Moreno; P Clavijo; Robert Edelman; J Davis; Marcelo B Sztein; F Sinigaglia; Elizabeth H Nardin
CD4+ T cell clones obtained from Plasmodium falciparum sporozoite-immunized volunteers recognize polymorphic sequences of the circumsporozoite protein.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):489-99.
1993: J Mauricio Calvo-Calle; G A de Oliveira; P Clavijo; Marilyn Maracic; James P Tam; Yi-An Lu; Elizabeth H Nardin; Ruth S Nussenzweig; A H Cochrane
Immunogenicity of multiple antigen peptides containing B and non-repeat T cell epitopes of the circumsporozoite protein of Plasmodium falciparum.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(4):1403-12.
1993: Elizabeth H Nardin; Ruth S Nussenzweig
T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stages.
Annual review of immunology 1993;11():687-727.
1992: J M Calle; Elizabeth H Nardin; P Clavijo; C Boudin; D Stüber; B Takacs; Ruth S Nussenzweig; A H Cochrane
Recognition of different domains of the Plasmodium falciparum CS protein by the sera of naturally infected individuals compared with those of sporozoite-immunized volunteers.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2695-701.
1992: Elizabeth H Nardin; Y D Munesinghe; Alberto Moreno; P Clavijo; M C Calle; Robert Edelman; J Davis; D Herrington; Ruth S Nussenzweig
T cell responses to repeat and non-repeat regions of the circumsporozoite protein detected in volunteers immunized with Plasmodium falciparum sporozoites.
Memórias do Instituto Oswaldo Cruz 1992;87 Suppl 3():223-7.
1991: D A Herrington; Elizabeth H Nardin; Genevieve A Losonsky; I C Bathurst; P J Barr; M R Hollingdale; Robert Edelman; Myron M Levine
Safety and immunogenicity of a recombinant sporozoite malaria vaccine against Plasmodium vivax.
The American journal of tropical medicine and hygiene 1991;45(6):695-701.
1991: D Y Munesinghe; P Clavijo; M C Calle; Ruth S Nussenzweig; Elizabeth H Nardin
Immunogenicity of multiple antigen peptides (MAP) containing T and B cell epitopes of the repeat region of the P. falciparum circumsporozoite protein.
European journal of immunology 1991;21(12):3015-20.
1991: D Herrington; J Davis; Elizabeth H Nardin; M Beier; Joseph F Cortese; H Eddy; Genevieve A Losonsky; M Hollingdale; Marcelo B Sztein; Myron M Levine
Successful immunization of humans with irradiated malaria sporozoites: humoral and cellular responses of the protected individuals.
The American journal of tropical medicine and hygiene 1991;45(5):539-47.
1991: Alberto Moreno; P Clavijo; Robert Edelman; J Davis; Marcelo B Sztein; D Herrington; Elizabeth H Nardin
Cytotoxic CD4+ T cells from a sporozoite-immunized volunteer recognize the Plasmodium falciparum CS protein.
International immunology 1991;3(10):997-1003.
1991: P Millet; William E Collins; J R Broderson; I Bathurst; Elizabeth H Nardin; Ruth S Nussenzweig
Inhibitory activity against Plasmodium vivax sporozoites induced by plasma from Saimiri monkeys immunized with circumsporozoite recombinant proteins or irradiated sporozoites.
The American journal of tropical medicine and hygiene 1991;45(1):44-8.
1991: Elizabeth H Nardin; P Clavijo; B Mons; Alex Van Belkum; T Ponnudurai; Ruth S Nussenzweig
T cell epitopes of the circumsporozoite protein of Plasmodium vivax. Recognition by lymphocytes of a sporozoite-immunized chimpanzee.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(5):1674-8.
1990: William E Collins; Ruth S Nussenzweig; T K Ruebush; I C Bathurst; Elizabeth H Nardin; H L Gibson; G H Campbell; P J Barr; J R Broderson; J C Skinner
Further studies on the immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax.
The American journal of tropical medicine and hygiene 1990;43(6):576-83.
1990: A H Cochrane; Elizabeth H Nardin; M de Arruda; Marilyn Maracic; P Clavijo; William E Collins; Ruth S Nussenzweig
Widespread reactivity of human sera with a variant repeat of the circumsporozoite protein of Plasmodium vivax.
The American journal of tropical medicine and hygiene 1990;43(5):446-51.
1990: Elizabeth H Nardin
T cell responses in a sporozoite-immunized human volunteer and a chimpanzee.
Immunology letters 1990;25(1-3):43-7.
1990: Elizabeth H Nardin; Ruth S Nussenzweig; R Altszuler; D Herrington; Myron M Levine; J Murphy; J Davis; I Bathurst; P Barr; P Romero
Cellular and humoral immune responses to a recombinant P. falciparum CS protein in sporozoite-immunized rodents and human volunteers.
Bulletin of the World Health Organization 1990;68 Suppl():85-7.
1990: D A Herrington; D F Clyde; J R Davis; S Baqar; J R Murphy; Joseph F Cortese; R S Bank; Elizabeth H Nardin; D DiJohn; R S Nussenzweig
Human studies with synthetic peptide sporozoite vaccine (NANP)3-TT and immunization with irradiated sporozoites.
Bulletin of the World Health Organization 1990;68 Suppl():33-7.
1989: Elizabeth H Nardin; D A Herrington; J Davis; Myron M Levine; D Stuber; B Takacs; P Caspers; P Barr; R Altszuler; P Clavijo
Conserved repetitive epitope recognized by CD4+ clones from a malaria-immunized volunteer.
Science (New York, N.Y.) 1989;246(4937):1603-6.
1989: M de Arruda; Elizabeth H Nardin; Ruth S Nussenzweig; A H Cochrane
Sero-epidemiological studies of malaria in Indian tribes and monkeys of the Amazon Basin of Brazil.
The American journal of tropical medicine and hygiene 1989;41(4):379-85.
1989: William E Collins; Ruth S Nussenzweig; W Ripley Ballou; T K Ruebush; Elizabeth H Nardin; J D Chulay; W R Majarian; James F Young; Gail Folena-Wasserman; I Bathurst
Immunization of Saimiri sciureus boliviensis with recombinant vaccines based on the circumsporozoite protein of Plasmodium vivax.
The American journal of tropical medicine and hygiene 1989;40(5):455-64.
1988: Myron M Levine; D Herrington; D Clyde; J Murphy; J Davis; R Nussenzweig; Elizabeth H Nardin; A Felix; E Heimer; D Gillesen
Malaria vaccines: experience with sporozoite vaccines against falciparum malaria.
The Southeast Asian journal of tropical medicine and public health 1988;19(3):369-74.
1988: Elizabeth H Nardin; P J Barr; E Heimer; H M Etlinger
Genetic restriction of the murine humoral response to a recombinant Plasmodium vivax circumsporozoite protein.
European journal of immunology 1988;18(7):1119-22.
1987: Elizabeth H Nardin; P J Barr; H L Gibson; William E Collins; Ruth S Nussenzweig; Victor Nussenzweig
Induction of sporozoite-specific memory cells in mice immunized with a recombinant Plasmodium vivax circumsporozoite protein.
European journal of immunology 1987;17(12):1763-7.
1987: G H Campbell; S B Aley; W Ripley Ballou; T Hall; W T Hockmeyer; S L Hoffman; M R Hollingdale; R J Howard; Jeffrey A Lyon; Elizabeth H Nardin
Use of synthetic and recombinant peptides in the study of host-parasite interactions in the malarias.
The American journal of tropical medicine and hygiene 1987;37(3):428-44.
1983: Fidel Zavala; A H Cochrane; Elizabeth H Nardin; R S Nussenzweig; V Nussenzweig
Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes.
The Journal of experimental medicine 1983;157(6):1947-57.
1983: F Santoro; A H Cochrane; V Nussenzweig; Elizabeth H Nardin; Ruth S Nussenzweig; R W Gwadz; A Ferreira
Structural similarities among the protective antigens of sporozoites from different species of malaria parasites.
The Journal of biological chemistry 1983;258(5):3341-5.