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Linda Narhi

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Cynthia H Li; Jenny Li; Linda O Narhi; Xichdao Nguyen; Joseph Pollastrini; Trace Tsuruda; Jie Wen; Zai-qing Wen; Mariana Dimitrova; Yijia Jiang
Effect of pH, temperature, and salt on the stability of Escherichia coli- and Chinese hamster ovary cell-derived IgG1 Fc.
Marisa K Joubert; Bruce A Kerwin; Linda O Narhi; Lei Zhou; Matthew P Baker; Naren Chirmule; Meghana Deshpande; Catherine Eakin; Theresa J Goletz; Martha Hokom; Vibha Jawa
Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses.
Feng He; Linda O Narhi; Gerald W Becker; Christopher E Woods; Vladimir Razinkov
High-throughput assessment of thermal and colloidal stability parameters for monoclonal antibody formulations.

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2012: Cynthia H Li; Jenny Li; Linda O Narhi; Xichdao Nguyen; Joseph Pollastrini; Trace Tsuruda; Jie Wen; Zai-qing Wen; Mariana Dimitrova; Yijia Jiang
Effect of pH, temperature, and salt on the stability of Escherichia coli- and Chinese hamster ovary cell-derived IgG1 Fc.
Biochemistry 2012;51(50):10056-65.
2012: Marisa K Joubert; Bruce A Kerwin; Linda O Narhi; Lei Zhou; Matthew P Baker; Naren Chirmule; Meghana Deshpande; Catherine Eakin; Theresa J Goletz; Martha Hokom; Vibha Jawa
Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses.
The Journal of biological chemistry 2012;287(30):25266-79.
2011: Feng He; Linda O Narhi; Gerald W Becker; Christopher E Woods; Vladimir Razinkov
High-throughput assessment of thermal and colloidal stability parameters for monoclonal antibody formulations.
Journal of pharmaceutical sciences 2011;100(12):5126-41.
2010: Feng He; Duke H Phan; Sabine Hogan; Robert Bailey; Gerald W Becker; Linda O Narhi; Vladimir Razinkov
Detection of IgG aggregation by a high throughput method based on extrinsic fluorescence.
Journal of pharmaceutical sciences 2010;99(6):2598-608.
2010: Feng He; Gerald W Becker; Jennifer R Litowski; Linda O Narhi; David N Brems; Vladimir Razinkov
High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions.
Analytical biochemistry 2010;399(1):141-3.
2010: Feng He; Sabine Hogan; Ramil F Latypov; Linda O Narhi; Vladimir Razinkov
High throughput thermostability screening of monoclonal antibody formulations.
Journal of pharmaceutical sciences 2010;99(4):1707-20.
2009: Songpon Deechongkit; Jie Wen; Linda O Narhi; Yijia Jiang; Sungae S Park; Justin Kim; Bruce A Kerwin
Physical and biophysical effects of polysorbate 20 and 80 on darbepoetin alfa.
Journal of pharmaceutical sciences 2009;98(9):3200-17.
2009: Linda O Narhi; Yijia Jiang; Shawn Cao; Kalman Benedek; Deborah Shnek
A critical review of analytical methods for subvisible and visible particles.
Current pharmaceutical biotechnology 2009;10(4):373-81.
2009: R Matthew Fesinmeyer; Sabine Hogan; Atul Saluja; Stephen R Brych; Eva Kras; Linda O Narhi; David N Brems; Yatin R Gokarn
Effect of ions on agitation- and temperature-induced aggregation reactions of antibodies.
Pharmaceutical research 2009;26(4):903-13.
2009: Yatin R Gokarn; R Matthew Fesinmeyer; Atul Saluja; Shawn Cao; Jane Dankberg; Andrew Goetze; Richard L Remmele; Linda O Narhi; David N Brems
Ion-specific modulation of protein interactions: anion-induced, reversible oligomerization of a fusion protein.
Protein science : a publication of the Protein Society 2009;18(1):169-79.
2006: Eric Hsu; Timothy D Osslund; Rebecca Nybo; Bao-Lu Chen; William C Kenney; C Fred Morris; Tsutomu Arakawa; Linda O Narhi
Enhanced stability of recombinant keratinocyte growth factor by mutagenesis.
Protein engineering, design & selection : PEDS 2006;19(4):147-53.
2003: Sampathkumar Krishnan; Eva Y Chi; Stephen J Wood; Brent S Kendrick; Cynthia Li; William Garzon-Rodriguez; Jette Wypych; Theodore W Randolph; Linda O Narhi; Anja Leona Biere; Martin Citron; John F Carpenter
Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis.
Biochemistry 2003;42(3):829-37.
2002: Tsutomu Arakawa; Tiansheng Li; Linda O Narhi
Recombinant production of native proteins from Escherichia coli.
Pharmaceutical biotechnology 2002;13():27-60.
2002: Tiansheng Li; Harvey Yamane; Tsutomu Arakawa; Linda O Narhi; John Philo
Effect of the intermolecular disulfide bond on the conformation and stability of glial cell line-derived neurotrophic factor.
Protein engineering 2002;15(1):59-64.
2001: D Markell; J Hui; Linda O Narhi; D Lau; C LeBel; D Aparisio; J Lile; S Jing; D Yui; Byeong S Chang
Pharmaceutical significance of the cyclic imide form of recombinant human glial cell line derived neurotrophic factor.
Pharmaceutical research 2001;18(9):1361-6.
2000: Anja Leona Biere; Stephen J Wood; Jette Wypych; Shirley Steavenson; Y Jiang; D Anafi; F W Jacobsen; Mark Jarosinski; GM Wu; Jean-Claude Louis; F Martin; Linda O Narhi; Martin Citron
Parkinson's disease-associated alpha-synuclein is more fibrillogenic than beta- and gamma-synuclein and cannot cross-seed its homologs.
The Journal of biological chemistry 2000;275(44):34574-9.
1999: Linda O Narhi; John Philo; B Sun; Byeong S Chang; Tsutomu Arakawa
Reversibility of heat-induced denaturation of the recombinant human megakaryocyte growth and development factor.
Pharmaceutical research 1999;16(6):799-807.
1999: B J Moellering; Steven K Yoshinaga; A Hui; J M Delaney; S Hara; Linda O Narhi; K R Westcott
Folding and purification of a recombinantly expressed interferon regulatory factor, IRF-4.
Protein expression and purification 1999;16(1):160-70.
1999: DJ Caughey; Linda O Narhi; Y Kita; S Y Meng; D Wen; W Chen; B J Ratzkin; J Fujimoto; T Iwahara; T Yamamoto; T Arakawa
Fractionation of polyclonal antibodies to fragments of a neuroreceptor using three increasingly chaotropic solvents.
Journal of chromatography. B, Biomedical sciences and applications 1999;728(1):49-57.
1999: Linda O Narhi; Stephen J Wood; Shirley Steavenson; Y Jiang; GM Wu; D Anafi; S A Kaufman; F Martin; K Sitney; Paul E Denis; Jean-Claude Louis; Jette Wypych; Anja Leona Biere; Martin Citron
Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation.
The Journal of biological chemistry 1999;274(14):9843-6.
1999: HS Lu; P R Fausset; Linda O Narhi; TP Horan; K Shinagawa; Grant Shimamoto; Tom Boone
Chemical modification and site-directed mutagenesis of methionine residues in recombinant human granulocyte colony-stimulating factor: effect on stability and biological activity.
Archives of biochemistry and biophysics 1999;362(1):1-11.
1999: D M Danilenko; Silvia Montestruque; John Philo; Tiansheng Li; D Hill; J Speakman; M Bahru; Ming Zhang; M Konishi; N Itoh; M Chirica; J Delaney; N Hernday; Frank Martin; S Hara; Jane Talvenheimo; Linda O Narhi; Tsutomu Arakawa
Recombinant rat fibroblast growth factor-16: structure and biological activity.
Archives of biochemistry and biophysics 1999;361(1):34-46.
1998: RD Rosenfeld; L Zeni; Andrew A Welcher; Linda O Narhi; Clarence Hale; J Marasco; J Delaney; T Gleason; John Philo; V Katta; J Hui; Jamie Baumgartner; M Graham; Kevin L Stark; W Karbon
Biochemical, biophysical, and pharmacological characterization of bacterially expressed human agouti-related protein.
Biochemistry 1998;37(46):16041-52.
1998: Tiansheng Li; Linda O Narhi; J Wen; John Philo; K Sitney; J Inoue; T Yamamoto; Tsutomu Arakawa
Interactions between NFkappaB and its inhibitor ikappaB: biophysical characterization of a NFkappaB/ikappaB-alpha complex.
Journal of protein chemistry 1998;17(8):757-63.
1998: James Hamburger; E Chen; Linda O Narhi; GM Wu; David N Brems
Multiple conformational states of a new hematopoietic cytokine (megakaryocyte growth and development factor): pH- and urea-induced denaturation.
Proteins 1998;32(4):495-503.
1998: Timothy D Osslund; Rashid Syed; E Singer; E W Hsu; Rebecca Nybo; B L Chen; Timothy Harvey; Tsutomu Arakawa; Linda O Narhi; A Chirino; C Fred Morris
Correlation between the 1.6 A crystal structure and mutational analysis of keratinocyte growth factor.
Protein science : a publication of the Protein Society 1998;7(8):1681-90.
1998: Linda O Narhi; Jette Wypych; Tiansheng Li; KE Langley; Tsutomu Arakawa
Changes in conformation and stability upon SCF/sKit complex formation.
Journal of protein chemistry 1998;17(5):387-96.
1998: J L Liu; K V Lu; T Eris; V Katta; K R Westcott; Linda O Narhi; HS Lu
In vitro methionine oxidation of recombinant human leptin.
Pharmaceutical research 1998;15(4):632-40.
1997: Linda O Narhi; DJ Caughey; TP Horan; Y Kita; D Chang; T Arakawa
Fractionation and characterization of polyclonal antibodies using three progressively more chaotropic solvents.
Analytical biochemistry 1997;253(2):246-52.
1997: Linda O Narhi; DJ Caughey; TP Horan; Y Kita; D Chang; T Arakawa
Effect of three elution buffers on the recovery and structure of monoclonal antibodies.
Analytical biochemistry 1997;253(2):236-45.
1997: C G Kolvenbach; Linda O Narhi; John Philo; Tiansheng Li; Ming Zhang; Tsutomu Arakawa
Granulocyte-colony stimulating factor maintains a thermally stable, compact, partially folded structure at pH2.
The journal of peptide research : official journal of the American Peptide Society 1997;50(4):310-8.
1997: Linda O Narhi; R Rosenfeld; Grant Shimamoto; R Lee; N Hawkins; Tiansheng Li; John Philo; J Wen; Tsutomu Arakawa
Comparison of solution properties of human and rat ciliary neurotrophic factor.
The journal of peptide research : official journal of the American Peptide Society 1997;50(4):300-9.
1997: RD Rosenfeld; J A Miller; Linda O Narhi; N Hawkins; V Katta; S Lauren; M A Weiss; Tsutomu Arakawa
Putative folding pathway of insulin-like growth factor-I.
Archives of biochemistry and biophysics 1997;342(2):298-305.
1997: Linda O Narhi; K H Aoki; John Philo; Tsutomu Arakawa
Changes in conformation and stability upon formation of complexes of erythropoietin (EPO) and soluble EPO receptor.
Journal of protein chemistry 1997;16(3):213-25.
1997: YR Hsu; GM Wu; EA Mendiaz; Rashid Syed; Jette Wypych; R Toso; M B Mann; Tom Boone; Linda O Narhi; HS Lu; KE Langley
The majority of stem cell factor exists as monomer under physiological conditions. Implications for dimerization mediating biological activity.
The Journal of biological chemistry 1997;272(10):6406-15.
1996: Byeong S Chang; R M Beauvais; Tsutomu Arakawa; Linda O Narhi; Aichun Dong; D I Aparisio; John F Carpenter
Formation of an active dimer during storage of interleukin-1 receptor antagonist in aqueous solution.
Biophysical journal 1996;71(6):3399-406.
1996: Linda O Narhi; John Philo; Tiansheng Li; M Zhang; B Samal; Tsutomu Arakawa
Induction of alpha-helix in the beta-sheet protein tumor necrosis factor-alpha: acid-induced denaturation.
Biochemistry 1996;35(35):11454-60.
1996: Linda O Narhi; John Philo; Tiansheng Li; M Zhang; B Samal; Tsutomu Arakawa
Induction of alpha-helix in the beta-sheet protein tumor necrosis factor-alpha: thermal- and trifluoroethanol-induced denaturation at neutral pH.
Biochemistry 1996;35(35):11447-53.
1996: HS Lu; YR Hsu; Linda O Narhi; S Karkare; F K Lin
Purification and characterization of human tissue prokallikrein and kallikrein isoforms expressed in Chinese hamster ovary cells.
Protein expression and purification 1996;8(2):227-37.
1996: YR Hsu; Linda O Narhi; C Spahr; KE Langley; HS Lu
In vitro methionine oxidation of Escherichia coli-derived human stem cell factor: effects on the molecular structure, biological activity, and dimerization.
Protein science : a publication of the Protein Society 1996;5(6):1165-73.
1996: HS Lu; M D Jones; J H Shieh; EA Mendiaz; D Feng; P Watler; Linda O Narhi; KE Langley
Isolation and characterization of a disulfide-linked human stem cell factor dimer. Biochemical, biophysical, and biological comparison to the noncovalently held dimer.
The Journal of biological chemistry 1996;271(19):11309-16.
1996: M D Jones; Linda O Narhi; W C Chang; HS Lu
Refolding and oxidation of recombinant human stem cell factor produced in Escherichia coli.
The Journal of biological chemistry 1996;271(19):11301-8.
1996: Tom Horan; J Wen; Linda O Narhi; V Parker; A Garcia; Tsutomu Arakawa; John Philo
Dimerization of the extracellular domain of granuloycte-colony stimulating factor receptor by ligand binding: a monovalent ligand induces 2:2 complexes.
Biochemistry 1996;35(15):4886-96.
1996: John Philo; K H Aoki; T Arakawa; Linda O Narhi; J Wen
Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interaction.
Biochemistry 1996;35(5):1681-91.
1995: Tsutomu Arakawa; P Holst; Linda O Narhi; John Philo; J Wen; S J Prestrelski; X Zhu; Douglas C Rees; GM Fox
The importance of Arg40 and 45 in the mitogenic activity and structural stability of basic fibroblast growth factor: effects of acidic amino acid substitutions.
Journal of protein chemistry 1995;14(5):263-74.
1995: T S Juan; E Hailman; M J Kelley; L A Busse; E Davy; Cyril J. Empig; Linda O Narhi; Samuel D Wright; H S Lichenstein
Identification of a lipopolysaccharide binding domain in CD14 between amino acids 57 and 64.
The Journal of biological chemistry 1995;270(10):5219-24.
1995: M D McGinley; Linda O Narhi; M J Kelley; E Davy; J Robinson; MF Rohde; Samuel D Wright; H S Lichenstein
CD14: physical properties and identification of an exposed site that is protected by lipopolysaccharide.
The Journal of biological chemistry 1995;270(10):5213-8.
1995: HS Lu; D Chang; John Philo; K Zhang; Linda O Narhi; N Liu; M Zhang; J Sun; J Wen; D Yanagihara
Studies on the structure and function of glycosylated and nonglycosylated neu differentiation factors. Similarities and differences of the alpha and beta isoforms.
The Journal of biological chemistry 1995;270(9):4784-91.
1995: Tsutomu Arakawa; Tom Horan; K Leong; S J Prestrelski; Linda O Narhi; S Hu
Structure and activity of granulocyte colony-stimulating factor derived from CHO cells containing cDNA coding for alternatively spliced sequences.
Archives of biochemistry and biophysics 1995;316(1):285-9.
1995: B B Samal; Tsutomu Arakawa; Tom Boone; T Jones; S J Prestrelski; Linda O Narhi; J Wen; G W Stearns; C A Crandall; J Pope
High level expression of human leukemia inhibitory factor (LIF) from a synthetic gene in Escherichia coli and the physical and biological characterization of the protein.
Biochimica et biophysica acta 1995;1260(1):27-34.
1994: B L Chen; Tsutomu Arakawa; E Hsu; Linda O Narhi; T J Tressel; S L Chien
Strategies to suppress aggregation of recombinant keratinocyte growth factor during liquid formulation development.
Journal of pharmaceutical sciences 1994;83(12):1657-61.
1994: Tsutomu Arakawa; Mitsuru Haniu; Linda O Narhi; J A Miller; Jane Talvenheimo; John Philo; H T Chute; C Matheson; J Carnahan; J C Louis
Formation of heterodimers from three neurotrophins, nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor.
The Journal of biological chemistry 1994;269(45):27833-9.
1994: S J Prestrelski; Tsutomu Arakawa; K Duker; W C Kenney; Linda O Narhi
The conformational stability of a non-covalent dimer of a platelet-derived growth factor-B mutant lacking the two cysteines involved in interchain disulfide bonds.
International journal of peptide and protein research 1994;44(4):357-63.
1994: KE Langley; EA Mendiaz; N Liu; Linda O Narhi; L Zeni; C M Parseghian; C L Clogston; I Leslie; J A Pope; HS Lu
Properties of variant forms of human stem cell factor recombinantly expressed in Escherichia coli.
Archives of biochemistry and biophysics 1994;311(1):55-61.
1993: Linda O Narhi; R Rosenfeld; J Wen; Tsutomu Arakawa; S J Prestrelski; John Philo
Acid-induced unfolding of brain-derived neurotrophic factor results in the formation of a monomeric "a state".
Biochemistry 1993;32(40):10819-25.
1993: John Philo; R Rosenfeld; Tsutomu Arakawa; J Wen; Linda O Narhi
Refolding of brain-derived neurotrophic factor from guanidine hydrochloride: kinetic trapping in a collapsed form which is incompetent for dimerization.
Biochemistry 1993;32(40):10812-8.
1993: R Rosenfeld; John Philo; Mitsuru Haniu; K Stoney; MF Rohde; GM Wu; Linda O Narhi; C Wong; T Boone; N N Hawkins
Sites of iodination in recombinant human brain-derived neurotrophic factor and its effect on neurotrophic activity.
Protein science : a publication of the Protein Society 1993;2(10):1664-74.
1993: T Arakawa; S J Prestrelski; Linda O Narhi; Tom Boone; W C Kenney
Cysteine 17 of recombinant human granulocyte-colony stimulating factor is partially solvent-exposed.
Journal of protein chemistry 1993;12(5):525-31.
1993: Mitsuru Haniu; Linda O Narhi; T Arakawa; S Elliott; MF Rohde
Recombinant human erythropoietin (rHuEPO): cross-linking with disuccinimidyl esters and identification of the interfacing domains in EPO.
Protein science : a publication of the Protein Society 1993;2(9):1441-51.
1993: Tsutomu Arakawa; Tom Horan; Linda O Narhi; Douglas C Rees; S G Schiffer; P L Holst; S J Prestrelski; L B Tsai; GM Fox
Production and characterization of an analog of acidic fibroblast growth factor with enhanced stability and biological activity.
Protein engineering 1993;6(5):541-6.
1993: Linda O Narhi; R Rosenfeld; Jane Talvenheimo; S J Prestrelski; Tsutomu Arakawa; J W Lary; C G Kolvenbach; R Hecht; T Boone; J A Miller
Comparison of the biophysical characteristics of human brain-derived neurotrophic factor, neurotrophin-3, and nerve growth factor.
The Journal of biological chemistry 1993;268(18):13309-17.
1993: RD Rosenfeld; N M Noone; S L Lauren; MF Rohde; Linda O Narhi; Tsutomu Arakawa
Mutation of Arg55/56 to Leu55/Ala56 in insulin-like growth factor-I results in two forms different in disulfide structure and native conformation but similar under reverse-phase conditions.
Journal of protein chemistry 1993;12(3):247-54.
1993: Linda O Narhi; Qing-xin Hua; Tsutomu Arakawa; GM Fox; L Tsai; R Rosenfeld; P Holst; J A Miller; Michael A Weiss
Role of native disulfide bonds in the structure and activity of insulin-like growth factor 1: genetic models of protein-folding intermediates.
Biochemistry 1993;32(19):5214-21.
1993: J A Miller; Linda O Narhi; Qing-xin Hua; R Rosenfeld; Tsutomu Arakawa; M Rohde; S Prestrelski; S Lauren; K S Stoney; L Tsai
Oxidative refolding of insulin-like growth factor 1 yields two products of similar thermodynamic stability: a bifurcating protein-folding pathway.
Biochemistry 1993;32(19):5203-13.
1993: C G Kolvenbach; S Elliott; R Sachdev; Tsutomu Arakawa; Linda O Narhi
Characterization of two fluorescent tryptophans in recombinant human granulocyte-colony stimulating factor: comparison of native sequence protein and tryptophan-deficient mutants.
Journal of protein chemistry 1993;12(2):229-36.
1993: Tsutomu Arakawa; L Hung; V Pan; T P Horan; C G Kolvenbach; Linda O Narhi
Analysis of the heat-induced denaturation of proteins using temperature gradient gel electrophoresis.
Analytical biochemistry 1993;208(2):255-9.
1993: Linda O Narhi; W C Kenney; S J Prestrelski; Tsutomu Arakawa; D Lyons; J Lary; D A Yphantis
Conformation of glutathione adduct and oxidized forms of platelet-derived growth factor.
International journal of peptide and protein research 1993;41(1):8-14.
1992: HS Lu; C L Clogston; Linda O Narhi; L A Merewether; W R Pearl; Tom Boone
Folding and oxidation of recombinant human granulocyte colony stimulating factor produced in Escherichia coli. Characterization of the disulfide-reduced intermediates and cysteine----serine analogs.
The Journal of biological chemistry 1992;267(13):8770-7.
1992: Tsutomu Arakawa; L Hung; Linda O Narhi
Stability of fungal alpha-amylase in sodium dodecylsulfate.
Journal of protein chemistry 1992;11(2):111-7.
1992: Tsutomu Arakawa; L Hung; M G McGinley; MF Rohde; Linda O Narhi
Induced resistance of trypsin to sodium dodecylsulfate upon complex formation with trypsin inhibitor.
Journal of protein chemistry 1992;11(2):171-6.
1992: H S Lichenstein; L A Busse; G A Smith; Linda O Narhi; M O McGinley; MF Rohde; J L Katzowitz; M M Zukowski
Cloning and characterization of a gene encoding extracellular metalloprotease from Streptomyces lividans.
Gene 1992;111(1):125-30.
1992: Linda O Narhi; Tsutomu Arakawa; M D McGinley; MF Rohde; K R Westcott
Circular dichroism of reduced and oxidized recombinant human epidermal growth factor.
International journal of peptide and protein research 1992;39(2):182-7.
1992: S J Prestrelski; Tsutomu Arakawa; C S Wu; K D O'Neal; K R Westcott; Linda O Narhi
Solution structure and dynamics of epidermal growth factor and transforming growth factor alpha.
The Journal of biological chemistry 1992;267(1):319-22.
1991: Linda O Narhi; Tsutomu Arakawa; K H Aoki; R Elmore; MF Rohde; T Boone; T W Strickland
The effect of carbohydrate on the structure and stability of erythropoietin.
The Journal of biological chemistry 1991;266(34):23022-6.
1991: Tsutomu Arakawa; D A Yphantis; J W Lary; Linda O Narhi; HS Lu; S J Prestrelski; C L Clogston; K M Zsebo; EA Mendiaz; Jette Wypych
Glycosylated and unglycosylated recombinant-derived human stem cell factors are dimeric and have extensive regular secondary structure.
The Journal of biological chemistry 1991;266(28):18942-8.
1991: Linda O Narhi; J Connor; MF Rohde; M G McGinley; Tsutomu Arakawa
Stoichiometric complexation of Streptomyces subtilisin inhibitor and subtilisin.
Journal of protein chemistry 1991;10(4):385-9.
1991: Linda O Narhi; W C Kenney; Tsutomu Arakawa
Conformational changes of recombinant human granulocyte-colony stimulating factor induced by pH and guanidine hydrochloride.
Journal of protein chemistry 1991;10(4):359-67.
1991: Tsutomu Arakawa; Linda O Narhi
Solvent modulation in hydrophobic interaction chromatography.
Biotechnology and applied biochemistry 1991;13(2):151-72.
1991: Linda O Narhi; Y Stabinsky; M Levitt; L Miller; R Sachdev; S Finley; S Park; C Kolvenbach; Tsutomu Arakawa; M Zukowski
Enhanced stability of subtilisin by three point mutations.
Biotechnology and applied biochemistry 1991;13(1):12-24.
1990: C G Kolvenbach; Linda O Narhi; K Lazenby; B Samal; Tsutomu Arakawa
Comparative study on proteinase R, T, and K from Tritirachiam album limber.
International journal of peptide and protein research 1990;36(4):387-91.
1990: Tsutomu Arakawa; J V Visger; M McGinley; MF Rohde; GM Fox; Linda O Narhi
Alteration in folding efficiency and conformation of recombinant human tumor necrosis factor-alpha by replacing cysteines 69 and 101 with aspartic acid 69 and arginine 101.
Protein engineering 1990;3(8):721-4.
1990: S Elliott; K D Fagin; Linda O Narhi; J A Miller; M Jones; R Koski; M Peters; P Hsieh; R Sachdev; RD Rosenfeld
Yeast-derived recombinant human insulin-like growth factor I: production, purification, and structural characterization.
Journal of protein chemistry 1990;9(1):95-104.
1989: Linda O Narhi; Y Kita; T Arakawa
Hydrophobic interaction chromatography in alkaline pH.
Analytical biochemistry 1989;182(2):266-70.
1989: Linda O Narhi; M F Rhode; P Hunt; Tsutomu Arakawa
The limited proteolysis of tumor necrosis factor-alpha.
Journal of protein chemistry 1989;8(5):669-77.
1989: Linda O Narhi; Tsutomu Arakawa
Sodium dodecyl sulfate polyacrylamide gel electrophoresis as a method for studying the stability of subtilisin.
Biochimica et biophysica acta 1989;990(2):144-9.
1988: Linda O Narhi; M Zukowski; Tsutomu Arakawa
Stability of aprA-subtilisin in sodium dodecyl sulfate.
Archives of biochemistry and biophysics 1988;261(1):161-9.