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Yoshihisa Nasa

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Myocardial Reperfusion

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Ryo Oikawa; Chihiro Hosoda; Yoshihisa Nasa; Takuya Daicho; Akito Tanoue; Gozoh Tsujimoto; Norio Takagi; Kouichi Tanonaka; Satoshi Takeo
Decreased susceptibility to salt-induced hypertension in subtotally nephrectomized mice lacking the vasopressin V1a receptor.
Ryo Oikawa; Yoshihisa Nasa; Rie Ishii; Tomoyuki Kuwaki; Akito Tanoue; Gozoh Tsujimoto; Satoshi Takeo
Vasopressin V1A receptor enhances baroreflex via the central component of the reflex arc.
Taka-aki Koshimizu; Yoshihisa Nasa; Akito Tanoue; Ryo Oikawa; Yuji Kawahara; Yasushi Kiyono; Tetsuya Adachi; Toshiki Tanaka; Tomoyuki Kuwaki; Toyoki Mori; Satoshi Takeo; Hitoshi Okamura; Gozoh Tsujimoto
V1a vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.

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All Publications

2010: Ryo Oikawa; Chihiro Hosoda; Yoshihisa Nasa; Takuya Daicho; Akito Tanoue; Gozoh Tsujimoto; Norio Takagi; Kouichi Tanonaka; Satoshi Takeo
Decreased susceptibility to salt-induced hypertension in subtotally nephrectomized mice lacking the vasopressin V1a receptor.
Cardiovascular research 2010;87(1):187-94.
2007: Ryo Oikawa; Yoshihisa Nasa; Rie Ishii; Tomoyuki Kuwaki; Akito Tanoue; Gozoh Tsujimoto; Satoshi Takeo
Vasopressin V1A receptor enhances baroreflex via the central component of the reflex arc.
European journal of pharmacology 2007;558(1-3):144-50.
2006: Taka-aki Koshimizu; Yoshihisa Nasa; Akito Tanoue; Ryo Oikawa; Yuji Kawahara; Yasushi Kiyono; Tetsuya Adachi; Toshiki Tanaka; Tomoyuki Kuwaki; Toyoki Mori; Satoshi Takeo; Hitoshi Okamura; Gozoh Tsujimoto
V1a vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7807-12.
2005: Yuji Kawahara; Kouichi Tanonaka; Takuya Daicho; Mikio Nawa; Ryo Oikawa; Yoshihisa Nasa; Satoshi Takeo
Preferable anesthetic conditions for echocardiographic determination of murine cardiac function.
Journal of pharmacological sciences 2005;99(1):95-104.
2005: Chihiro Hosoda; Taka-aki Koshimizu; Akito Tanoue; Yoshihisa Nasa; Ryo Oikawa; Takashi Tomabechi; Shinya Fukuda; Hitomi Shinoura; Sayuri Oshikawa; Satoshi Takeo; Tadaichi Kitamura; Susanna Cotecchia; Gozoh Tsujimoto
Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation.
Molecular pharmacology 2005;67(3):912-22.
2003: Toshiyuki Maki; Yoshihisa Nasa; Kouichi Tanonaka; Masaya Takahashi; Satoshi Takeo
Direct inhibition of neutral endopeptidase in vasopeptidase inhibitor-mediated amelioration of cardiac remodeling in rats with chronic heart failure.
Molecular and cellular biochemistry 2003;254(1-2):265-73.
2003: Akito Tanoue; Taka-aki Koshimizu; Katsushi Shibata; Yoshihisa Nasa; Satoshi Takeo; Gozoh Tsujimoto
Insights into alpha1 adrenoceptor function in health and disease from transgenic animal studies.
Trends in endocrinology and metabolism: TEM 2003;14(3):107-13.
2003: Toshiyuki Maki; Yoshihisa Nasa; Kouichi Tanonaka; Masaya Takahashi; Satoshi Takeo
Beneficial effects of sampatrilat, a novel vasopeptidase inhibitor, on cardiac remodeling and function of rats with chronic heart failure following left coronary artery ligation.
The Journal of pharmacology and experimental therapeutics 2003;305(1):97-105.
2002: Akito Tanoue; Yoshihisa Nasa; Taka-aki Koshimizu; Hitomi Shinoura; Sayuri Oshikawa; Takayuki Kawai; Sachie Sunada; Satoshi Takeo; Gozoh Tsujimoto
The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction.
The Journal of clinical investigation 2002;109(6):765-75.
2001: Hiroyuki Yoshida; M Takahashi; Kouichi Tanonaka; Toshiyuki Maki; Yoshihisa Nasa; Satoshi Takeo
Effects of ACE inhibition and angiotensin II type 1 receptor blockade on cardiac function and G proteins in rats with chronic heart failure.
British journal of pharmacology 2001;134(1):150-60.
2001: Toshiyuki Maki; Yoshihisa Nasa; F Yamaguchi; Hiroyuki Yoshida; M Mori; T Takada; E Horikawa; K Okano; Satoshi Takeo
Long-term treatment with neutral endopeptidase inhibitor improves cardiac function and reduces natriuretic peptides in rats with chronic heart failure.
Cardiovascular research 2001;51(3):608-17.
2000: Satoshi Takeo; Yoshihisa Nasa; Kouichi Tanonaka; F Yamaguchi; K Yabe; H Hayashi; N S Dhalla
Role of cardiac renin-angiotensin system in sarcoplasmic reticulum function and gene expression in the ischemic-reperfused heart.
Molecular and cellular biochemistry 2000;212(1-2):227-35.
1999: Satoshi Takeo; Yoshihisa Nasa
Role of energy metabolism in the preconditioned heart--a possible contribution of mitochondria.
Cardiovascular research 1999;43(1):32-43.
1999: F Yamaguchi; Ken-ichiro Kawana; Kouichi Tanonaka; I Kamano; T Igarashi; E Gen; Y Fujimoto; Toshiyuki Maki; A Sanbe; Yoshihisa Nasa; Satoshi Takeo
Improvement of exercise capacity of rats with chronic heart failure by long-term treatment with trandolapril.
British journal of pharmacology 1999;126(7):1585-92.
1998: Satoshi Takeo; Yoshihisa Nasa; Kouichi Tanonaka; K Yabe; M Nojiri; M Hayashi; H Sasaki; K Ida; K Yanai
Effects of long-term treatment with eicosapentaenoic acid on the heart subjected to ischemia/reperfusion and hypoxia/reoxygenation in rats.
Molecular and cellular biochemistry 1998;188(1-2):199-208.
1998: H Toyoshima; Yoshihisa Nasa; Y Hashizume; Y Koseki; Y Isayama; Y Kohsaka; T Yamada; Satoshi Takeo
Modulation of cAMP-mediated vasorelaxation by endothelial nitric oxide and basal cGMP in vascular smooth muscle.
Journal of cardiovascular pharmacology 1998;32(4):543-51.
1998: Yoshihisa Nasa; M Hayashi; H Sasaki; J Hayashi; Satoshi Takeo
Long-term supplementation with eicosapentaenoic acid salvages cardiomyocytes from hypoxia/reoxygenation-induced injury in rats fed with fish-oil-deprived diet.
Japanese journal of pharmacology 1998;77(2):137-46.
1998: Yoshihisa Nasa; Hiroyuki Yoshida; M Urata; K Uchibayashi; Y Tsunoda; K Kamigata; Satoshi Takeo
Effects of the antihypertensive agent, cicletanine, on noradrenaline release and vasoconstriction in perfused mesenteric artery of SHR.
British journal of pharmacology 1998;123(3):427-34.
1998: H Toyoshima; Yoshihisa Nasa; Y Kohsaka; Y Isayama; F Yamaguchi; A Sanbe; Satoshi Takeo
The effect of chronic treatment with trandolapril on cyclic AMP-and cyclic GMP-dependent relaxations in aortic segments of rats with chronic heart failure.
British journal of pharmacology 1998;123(2):344-52.
1997: Yoshihisa Nasa; Y Sakamoto; A Sanbe; H Sasaki; F Yamaguchi; Satoshi Takeo
Changes in fatty acid compositions of myocardial lipids in rats with heart failure following myocardial infarction.
Molecular and cellular biochemistry 1997;176(1-2):179-89.
1997: Yoshihisa Nasa; K Yabe; Satoshi Takeo
Beta-adrenoceptor stimulation-mediated preconditioning-like cardioprotection in perfused rat hearts.
Journal of cardiovascular pharmacology 1997;29(4):436-43.
1997: K Yabe; Yoshihisa Nasa; M Sato; R Iijima; Satoshi Takeo
Preconditioning preserves mitochondrial function and glycolytic flux during an early period of reperfusion in perfused rat hearts.
Cardiovascular research 1997;33(3):677-85.
1997: Yoshihisa Nasa; H Kume; Satoshi Takeo
Acetylcholine-induced vasoconstrictor response of coronary vessels in rats: a possible contribution of M2 muscarinic receptor activation.
Heart and vessels 1997;12(4):179-91.
1997: F Yamaguchi; Yoshihisa Nasa; K Yabe; S Ohba; Y Hashizume; H Ohaku; Kazuhisa Furuhama; Satoshi Takeo
Activation of cardiac muscarinic receptor and ischemic preconditioning effects in in situ rat heart.
Heart and vessels 1997;12(2):74-83.
1997: Y Ono; X Wu; A Noda; H Noda; Satoshi Takeo; Yoshihisa Nasa; Y Isayama; M Imai; Nobuyuki Sera
beta-Adrenoreceptor antagonistic actions and mutagenicities of R(+)- and S(-)-enantiomers of N-desisopropylpropranolol and its N-acetyl conjugate.
Biological & pharmaceutical bulletin 1997;20(1):61-5.
1996: Yoshihisa Nasa; H Toyoshima; H Ohaku; Y Hashizume; A Sanbe; Satoshi Takeo
Impairment of cGMP- and cAMP-mediated vasorelaxations in rats with chronic heart failure.
The American journal of physiology 1996;271(6 Pt 2):H2228-37.
1996: Y Okumura; Yoshihisa Nasa; A Sanbe; W Toga; Satoshi Takeo
Effects of long-term treatment with trandolapril on augmented vasoconstriction in rats with chronic heart failure.
Journal of cardiac failure 1996;2(4):301-10.
1995: M Hayashi; Yoshihisa Nasa; Kouichi Tanonaka; H Sasaki; R Miyake; J Hayashi; Satoshi Takeo
The effects of long-term treatment with eicosapentaenoic acid and docosahexaenoic acid on hypoxia/rexoygenation injury of isolated cardiac cells in adult rats.
Journal of molecular and cellular cardiology 1995;27(9):2031-41.
1995: Satoshi Takeo; J X Liu; Kouichi Tanonaka; Yoshihisa Nasa; K Yabe; H Tanahashi; H Sudo
Reperfusion at reduced flow rates enhances postischemic contractile recovery of perfused heart.
The American journal of physiology 1995;268(6 Pt 2):H2384-95.
1995: K Yabe; Yoshihisa Nasa; Satoshi Takeo
Hypoxic preconditioning in isolated rat hearts: non-involvement of activation of adenosine A1 receptor, Gi protein, and ATP-sensitive K+ channel.
Heart and vessels 1995;10(6):294-303.
1994: N Okazaki; Kouichi Tanonaka; Yoshihisa Nasa; N Takagi; T Yamasaki; S Yoshida; Satoshi Takeo
Hyperresponsiveness of cardiac muscles to histamine in reserpine-treated guinea pigs.
Japanese heart journal 1994;35(5):661-71.
1993: Yoshihisa Nasa; H Hashizume; A N Hoque; Y Abiko
Protective effect of crataegus extract on the cardiac mechanical dysfunction in isolated perfused working rat heart.
Arzneimittel-Forschung 1993;43(9):945-9.
1993: A N Hoque; Yoshihisa Nasa; Y Abiko
Cardioprotective effect of d-propranolol in ischemic-reperfused isolated rat hearts.
European journal of pharmacology 1993;236(2):269-77.
1993: K Miyake; Kouichi Tanonaka; Yoshihisa Nasa; N Takagi; T Tsuchiya; M Yoshizawa; Y Fujioka; Satoshi Takeo
Effects of naftidrofuryl oxalate on microsphere embolism-induced changes in tricarboxylic acid cycle intermediates of rats.
European journal of pharmacology 1993;235(1):75-81.
1992: Yoshihisa Nasa; A N Hoque; K Ichihara; Y Abiko
Cardioprotective effect of pindolol in ischemic-reperfused isolated rat hearts.
European journal of pharmacology 1992;213(2):171-81.
1992: Yoshihisa Nasa; K Ichihara; R Yoshida; Y Abiko
Positive inotropic and negative chronotropic effects of (-)-cis-diltiazem in rat isolated atria.
British journal of pharmacology 1992;105(3):696-702.
1991: I Miura; Yoshihisa Nasa; K Ichihara; Y Abiko
The inhibitory effect of bevantolol on the accumulation of non-esterified fatty acids during ischaemia in the dog heart in situ.
Clinical and experimental pharmacology & physiology 1991;18(4):259-62.
1990: Yoshihisa Nasa; K Ichihara; Y Abiko
Both d-cis- and l-cis-diltiazem have anti-ischemic action in the isolated, perfused working rat heart.
The Journal of pharmacology and experimental therapeutics 1990;255(2):680-9.
1990: K Sakai; K Ichihara; Yoshihisa Nasa; M Kamigaki; Y Abiko
Dichloroacetate attenuates myocardial acidosis and metabolic changes induced by partial occlusion of the coronary artery in dogs.
Archives internationales de pharmacodynamie et de thérapie 1990;307():92-108.
1990: Yoshihisa Nasa; K Ichihara; Y Abiko
Myocardial non-esterified fatty acids during normoxia and ischemia in Langendorff and working rat hearts.
Japanese journal of pharmacology 1990;53(1):129-33.
1990: Y Hara; K Nakamura; Yoshihisa Nasa; K Ichihara; Y Abiko
Changes in myocardial nonesterified fatty acids during ischemia and reperfusion in isolated, perfused, working rat hearts.
Heart and vessels 1990;6(1):21-30.