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Stanley Nattel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Benito Begoña; Nattel Stanley
Exercise training as a treatment for heart failure: potential mechanisms and clinical implications.
Del Duca Danny; Wong Guoruey; Trieu Phan; Rodaros Demetra; Kouremenos Athanasios; Tadevosyan Artavazd; Vaniotis George; Villeneuve Louis R; Tchervenkov Christo I; Nattel Stanley; Allen Bruce G; Hébert Terence E; Rohlicek Charles V
Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model.
Kirchhof Paulus; Bax Jeroen; Blomstrom-Lundquist Carina; Calkins Hugh; Camm A John; Cappato Ricardo; Cosio Francisco; Crijns Harry; Diener Hans-Christian; Goette Andreas; Israel Carsten W; Kuck Karl-Heinz; Lip Gregory Y H; Nattel Stanley; Page Richard L; Ravens Ursula; Schotten Ulrich; Steinbeck Gerhard; Vardas Panos; Waldo Albert; Wegscheider Karl; Willems Stephan; Breithardt Günter
Early and comprehensive management of atrial fibrillation: proceedings from the 2nd AFNET/EHRA consensus conference on atrial fibrillation entitled 'research perspectives in atrial fibrillation'.

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All Publications

2009: Benito Begoña; Nattel Stanley
Exercise training as a treatment for heart failure: potential mechanisms and clinical implications.
The Journal of physiology 2009;587(Pt 21):5011-3.
2009: Del Duca Danny; Wong Guoruey; Trieu Phan; Rodaros Demetra; Kouremenos Athanasios; Tadevosyan Artavazd; Vaniotis George; Villeneuve Louis R; Tchervenkov Christo I; Nattel Stanley; Allen Bruce G; Hébert Terence E; Rohlicek Charles V
Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model.
The Journal of thoracic and cardiovascular surgery 2009;138(3):538-46, 546.e1.
2009: Kirchhof Paulus; Bax Jeroen; Blomstrom-Lundquist Carina; Calkins Hugh; Camm A John; Cappato Ricardo; Cosio Francisco; Crijns Harry; Diener Hans-Christian; Goette Andreas; Israel Carsten W; Kuck Karl-Heinz; Lip Gregory Y H; Nattel Stanley; Page Richard L; Ravens Ursula; Schotten Ulrich; Steinbeck Gerhard; Vardas Panos; Waldo Albert; Wegscheider Karl; Willems Stephan; Breithardt Günter
Early and comprehensive management of atrial fibrillation: proceedings from the 2nd AFNET/EHRA consensus conference on atrial fibrillation entitled 'research perspectives in atrial fibrillation'.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2009;11(7):860-85.
2009: Chauvet Cristina; Ménard Annie; Tremblay Johanne; Xiao Chunjie; Shi Yanfen; L'Heureux Nathalie; Cardin Sophie; Tardif Jean-Claude; Nattel Stanley; Deng Alan Y
Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis.
Hypertension research : official journal of the Japanese Society of Hypertension 2009;32(7):631-7.
2009: Qi XiaoYan; Yeh Yung-Hsin; Chartier Denis; Xiao Ling; Tsuji Yukiomi; Brundel Bianca J J M; Kodama Itsuo; Nattel Stanley
The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long-QT syndrome.
Circulation. Arrhythmia and electrophysiology 2009;2(3):295-304.
2009: Nattel Stanley
Cell calcium, repolarization changes, and spontaneous postshock fibrillation in failing hearts: causes of refibrillation and electrical storm.
Heart rhythm : the official journal of the Heart Rhythm Society 2009;6(6):793-5.
2009: Maguy Ange; Le Bouter Sabrina; Comtois Philippe; Chartier Denis; Villeneuve Louis; Wakili Reza; Nishida Kunihiro; Nattel Stanley
Ion channel subunit expression changes in cardiac Purkinje fibers: a potential role in conduction abnormalities associated with congestive heart failure.
Circulation research 2009;104(9):1113-22.
2009: Ly Hung Q; Nattel Stanley
Stem cells are not proarrhythmic: letting the genie out of the bottle.
Circulation 2009;119(13):1824-31.
2009: Nattel Stanley
Calcium-activated potassium current: a novel ion channel candidate in atrial fibrillation.
The Journal of physiology 2009;587(Pt 7):1385-6.
2009: Joyner Michael J; Nattel Stanley
Fast and furious: new ways to think about, study and treat cardiac arrhythmias.
The Journal of physiology 2009;587(Pt 7):1383-4.
2009: Yeh Yung-Hsin; Burstein Brett; Qi Xiao Yan; Sakabe Masao; Chartier Denis; Comtois Philippe; Wang Zhiguo; Kuo Chi-Tai; Nattel Stanley
Funny current downregulation and sinus node dysfunction associated with atrial tachyarrhythmia: a molecular basis for tachycardia-bradycardia syndrome.
Circulation 2009;119(12):1576-85.
2009: Greiser Maura; Neuberger Hans-Ruprecht; Harks Erik; El-Armouche Ali; Boknik Peter; de Haan Sunniva; Verheyen Fons; Verheule Sander; Schmitz Wilhelm; Ravens Ursula; Nattel Stanley; Allessie Maurits A; Dobrev Dobromir; Schotten Ulrich
Distinct contractile and molecular differences between two goat models of atrial dysfunction: AV block-induced atrial dilatation and atrial fibrillation.
Journal of molecular and cellular cardiology 2009;46(3):385-94.
2009: Benjamin Emelia J; Chen Peng-Sheng; Bild Diane E; Mascette Alice M; Albert Christine M; Alonso Alvaro; Calkins Hugh; Connolly Stuart J; Curtis Anne B; Darbar Dawood; Ellinor Patrick T; Go Alan S; Goldschlager Nora F; Heckbert Susan R; Jalife José; Kerr Charles R; Levy Daniel; Lloyd-Jones Donald M; Massie Barry M; Nattel Stanley; Olgin Jeffrey E; Packer Douglas L; Po Sunny S; Tsang Teresa S M; Van Wagoner David R; Waldo Albert L; Wyse D George
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop.
Circulation 2009;119(4):606-18.
2009: Gaborit Nathalie; Wichter Thomas; Varro Andras; Szuts Viktoria; Lamirault Guillaume; Eckardt Lars; Paul Matthias; Breithardt Günter; Schulze-Bahr Eric; Escande Denis; Nattel Stanley; Demolombe Sophie
Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases.
European heart journal 2009;30(4):487-96.
2009: Michael Georghia; Xiao Ling; Qi Xiao-Yan; Dobrev Dobromir; Nattel Stanley
Remodelling of cardiac repolarization: how homeostatic responses can lead to arrhythmogenesis.
Cardiovascular research 2009;81(3):491-9.
2009: Lemola Kristina; Khan Razi; Nattel Stanley; Talajic Mario; Roy Denis; Guerra Peter G; Lemola Sakari; Dubuc Marc; Thibault Bernard; Macle Laurent; Khairy Paul
Ventricular proarrhythmic effects of atrial fibrillation are modulated by depolarization and repolarization anomalies in patients with left ventricular dysfunction.
Pacing and clinical electrophysiology : PACE 2009;32(1):99-105.
2009: Nattel Stanley
G-protein signaling and arrhythmogenic atrial remodeling: relevance to novel therapeutic targets in atrial fibrillation.
Heart rhythm : the official journal of the Heart Rhythm Society 2009;6(1):85-6.
2009: Ehrlich Joachim R; Nattel Stanley
Novel approaches for pharmacological management of atrial fibrillation.
Drugs 2009;69(7):757-74.
2008: Van Wagoner David R; Nattel Stanley
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy.
Journal of molecular and cellular cardiology 2008;45(6):707-8.
2008: Cardin Sophie; Pelletier Patricia; Libby Eric; Le Bouter Sabrina; Xiao Ling; Kääb Stefan; Demolombe Sophie; Glass Leon; Nattel Stanley
Marked differences between atrial and ventricular gene-expression remodeling in dogs with experimental heart failure.
Journal of molecular and cellular cardiology 2008;45(6):821-31.
2008: Ke Lei; Qi Xiao Yan; Dijkhuis Anne-Jan; Chartier Denis; Nattel Stanley; Henning Robert H; Kampinga Harm H; Brundel Bianca J J M
Calpain mediates cardiac troponin degradation and contractile dysfunction in atrial fibrillation.
Journal of molecular and cellular cardiology 2008;45(5):685-93.
2008: Nattel Stanley; Duker Göran; Carlsson Leif
Model systems for the discovery and development of antiarrhythmic drugs.
Progress in biophysics and molecular biology 2008;98(2-3):328-39.
2008: Deng Alan Y; Nattel Stanley; Shi Yanfen; L'heureux Nathalie; Cardin Sophie; Ménard Annie; Roy Julie; Tardif Jean-Claude
Distinct genomic replacements from Lewis correct diastolic dysfunction, attenuate hypertension, and reduce left ventricular hypertrophy in Dahl salt-sensitive rats.
Journal of hypertension 2008;26(10):1935-43.
2008: Dobrev Dobromir; Nattel Stanley
Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics.
Journal of cardiovascular pharmacology 2008;52(4):293-9.
2008: Qi Xiao Yan; Yeh Yung-Hsin; Xiao Ling; Burstein Brett; Maguy Ange; Chartier Denis; Villeneuve Louis R; Brundel Bianca J J M; Dobrev Dobromir; Nattel Stanley
Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current.
Circulation research 2008;103(8):845-54.
2008: Comtois Philippe; Sakabe Masao; Vigmond Edward J; Munoz Mauricio; Texier Anne; Shiroshita-Takeshita Akiko; Nattel Stanley
Mechanisms of atrial fibrillation termination by rapidly unbinding Na+ channel blockers: insights from mathematical models and experimental correlates.
American journal of physiology. Heart and circulatory physiology 2008;295(4):H1489-504.
2008: Palardy Maryse; Ducharme Anique; Nattel Stanley; Tardif Jean-Claude; White Michel; Racine Normand; Tétreault Karine; Dabouz Farida; Talajic Mario; Roy Denis;
Absence of protective effect of renin-angiotensin system inhibitors on atrial fibrillation development: insights from the Canadian Trial of Atrial Fibrillation (CTAF).
The Canadian journal of cardiology 2008;24(9):709-13.
2008: Nattel Stanley
Inward rectifier-funny current balance and spontaneous automaticity: cautionary notes for biologic pacemaker development.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(9):1318-9.
2008: Xiao Ling; Coutu Pierre; Villeneuve Louis R; Tadevosyan Artavazd; Maguy Ange; Le Bouter Sabrina; Allen Bruce G; Nattel Stanley
Mechanisms underlying rate-dependent remodeling of transient outward potassium current in canine ventricular myocytes.
Circulation research 2008;103(7):733-42.
2008: Xiao Ling; Xiao Jiening; Luo Xiaobin; Lin Huixian; Wang Zhiguo; Nattel Stanley
Feedback remodeling of cardiac potassium current expression: a novel potential mechanism for control of repolarization reserve.
Circulation 2008;118(10):983-92.
2008: Biliczki Peter; Girmatsion Zenawit; Harenkamp Sabine; Anneken Lars; Brandes Ralf P; Varro Andras; Marschall Christoph; Herrera Daniel; Hohnloser Stefan H; Nattel Stanley; Ehrlich Joachim R
Cellular properties of C-terminal KCNH2 long QT syndrome mutations: description and divergence from clinical phenotypes.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(8):1159-67.
2008: Stillitano Francesca; Lonardo Giuseppe; Zicha Stephen; Varro Andras; Cerbai Elisabetta; Mugelli Alessandro; Nattel Stanley
Molecular basis of funny current (If) in normal and failing human heart.
Journal of molecular and cellular cardiology 2008;45(2):289-99.
2008: Burstein Brett; Nattel Stanley
Atrial structural remodeling as an antiarrhythmic target.
Journal of cardiovascular pharmacology 2008;52(1):4-10.
2008: Nattel Stanley
Evolving developments in the therapeutics of atrial fibrillation: addressing an unmet need.
Journal of cardiovascular pharmacology 2008;52(1):1-3.
2008: Sun Hui; Varela Diego; Chartier Denis; Ruben Peter C; Nattel Stanley; Zamponi Gerald W; Leblanc Normand
Differential interactions of Na+ channel toxins with T-type Ca2+ channels.
The Journal of general physiology 2008;132(1):101-13.
2008: Diness Thomas G; Yeh Yung-Hsin; Qi Xiao Yan; Chartier Denis; Tsuji Yukiomi; Hansen Rie S; Olesen Soren-Peter; Grunnet Morten; Nattel Stanley
Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome.
Cardiovascular research 2008;79(1):61-9.
2008: Yeh Yung-Hsin; Wakili Reza; Qi Xiao-Yan; Chartier Denis; Boknik Peter; Kääb Stefan; Ravens Ursula; Coutu Pierre; Dobrev Dobromir; Nattel Stanley
Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure.
Circulation. Arrhythmia and electrophysiology 2008;1(2):93-102.
2008: Roy Denis; Talajic Mario; Nattel Stanley; Wyse D George; Dorian Paul; Lee Kerry L; Bourassa Martial G; Arnold J Malcolm O; Buxton Alfred E; Camm A John; Connolly Stuart J; Dubuc Marc; Ducharme Anique; Guerra Peter G; Hohnloser Stefan H; Lambert Jean; Le Heuzey Jean-Yves; O'Hara Gilles; Pedersen Ole Dyg; Rouleau Jean-Lucien; Singh Bramah N; Stevenson Lynne Warner; Stevenson William G; Thibault Bernard; Waldo Albert L;
Rhythm control versus rate control for atrial fibrillation and heart failure.
The New England journal of medicine 2008;358(25):2667-77.
2008: Nattel Stanley
Effects of heart disease on cardiac ion current density versus current amplitude: important conceptual subtleties in the language of arrhythmogenic ion channel remodeling.
Circulation research 2008;102(11):1298-300.
2008: Nattel Stanley
Complex fractionated atrial electrograms: can they be made simple?
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(6):855-6.
2008: Brundel Bianca J J M; Ke Lei; Dijkhuis Anne-Jan; Qi XiaoYan; Shiroshita-Takeshita Akiko; Nattel Stanley; Henning Robert H; Kampinga Harm H
Heat shock proteins as molecular targets for intervention in atrial fibrillation.
Cardiovascular research 2008;78(3):422-8.
2008: Andalib Ali; Brugada Ramon; Nattel Stanley
Atrial fibrillation: evidence for genetically determined disease.
Current opinion in cardiology 2008;23(3):176-83.
2008: Nattel Stanley; Burstein Brett; Dobrev Dobromir
Atrial remodeling and atrial fibrillation: mechanisms and implications.
Circulation. Arrhythmia and electrophysiology 2008;1(1):62-73.
2008: Burstein Brett; Libby Eric; Calderone Angelino; Nattel Stanley
Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences.
Circulation 2008;117(13):1630-41.
2008: Sakabe Masao; Shiroshita-Takeshita Akiko; Maguy Ange; Brundel Bianca J J M; Fujiki Akira; Inoue Hiroshi; Nattel Stanley
Effects of a heat shock protein inducer on the atrial fibrillation substrate caused by acute atrial ischaemia.
Cardiovascular research 2008;78(1):63-70.
2008: Shimano Masayuki; Tsuji Yukiomi; Inden Yasuya; Kitamura Kazuhisa; Uchikawa Tomohiro; Harata Shuji; Nattel Stanley; Murohara Toyoaki
Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(3):451-9.
2008: Burstein Brett; Nattel Stanley
Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation.
Journal of the American College of Cardiology 2008;51(8):802-9.
2008: Ehrlich Joachim R; Biliczki Peter; Hohnloser Stefan H; Nattel Stanley
Atrial-selective approaches for the treatment of atrial fibrillation.
Journal of the American College of Cardiology 2008;51(8):787-92.
2008: Nattel Stanley
Repolarization indices or calcium-current recovery/repolarization balance: what determines torsadogenesis?
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(2):280-1.
2008: Prystowsky Eric N; Jaïs Pierre; Kowey Peter; Nattel Stanley; Ruskin Jeremy N
Case studies with the experts: management decisions in atrial fibrillation.
Journal of cardiovascular electrophysiology 2008;19 Suppl 1():S1-12; quiz S13-5.
2008: Lemola Kristina; Chartier Denis; Yeh Yung-Hsin; Dubuc Marc; Cartier Raymond; Armour Andrew; Ting Michael; Sakabe Masao; Shiroshita-Takeshita Akiko; Comtois Philippe; Nattel Stanley
Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia.
Circulation 2008;117(4):470-7.
2008: Voigt Niels; Maguy Ange; Yeh Yung-Hsin; Qi Xiaoyan; Ravens Ursula; Dobrev Dobromir; Nattel Stanley
Changes in I K, ACh single-channel activity with atrial tachycardia remodelling in canine atrial cardiomyocytes.
Cardiovascular research 2008;77(1):35-43.
2007: Cherry Elizabeth M; Ehrlich Joachim R; Nattel Stanley; Fenton Flavio H
Pulmonary vein reentry--properties and size matter: insights from a computational analysis.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(12):1553-62.
2007: Burstein Brett; Maguy Ange; Clément Robert; Gosselin Hugues; Poulin Francine; Ethier Nathalie; Tardif Jean-Claude; Hébert Terence E; Calderone Angelino; Nattel Stanley
Effects of resveratrol (trans-3,5,4'-trihydroxystilbene) treatment on cardiac remodeling following myocardial infarction.
The Journal of pharmacology and experimental therapeutics 2007;323(3):916-23.
2007: Burstein Brett; Qi Xiao-Yan; Yeh Yung-Hsin; Calderone Angelino; Nattel Stanley
Atrial cardiomyocyte tachycardia alters cardiac fibroblast function: a novel consideration in atrial remodeling.
Cardiovascular research 2007;76(3):442-52.
2007: Yeh Y-H; Qi X; Shiroshita-Takeshita A; Liu J; Maguy A; Chartier D; Hebert T; Wang Z; Nattel S
Atrial tachycardia induces remodelling of muscarinic receptors and their coupled potassium currents in canine left atrial and pulmonary vein cardiomyocytes.
British journal of pharmacology 2007;152(7):1021-32.
2007: Sakabe Masao; Shiroshita-Takeshita Akiko; Maguy Ange; Dumesnil Chloe; Nigam Anil; Leung Tack-Ki; Nattel Stanley
Omega-3 polyunsaturated fatty acids prevent atrial fibrillation associated with heart failure but not atrial tachycardia remodeling.
Circulation 2007;116(19):2101-9.
2007: Shimano Masayuki; Tsuji Yukiomi; Yoshida Yukihiko; Inden Yasuya; Tsuboi Naoya; Itoh Teruo; Suzuki Hirohiko; Muramatsu Takashi; Okada Taro; Harata Shuji; Yamada Takumi; Hirayama Haruo; Nattel Stanley; Murohara Toyoaki
Acute and chronic effects of cardiac resynchronization in patients developing heart failure with long-term pacemaker therapy for acquired complete atrioventricular block.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2007;9(10):869-74.
2007: Nattel Stanley; Khan Razi A
Protein kinase C, connexin43, and ischemic preconditioning: complex interactions of potential importance for controlling arrhythmias.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(9):1194-5.
2007: El-Armouche Ali; Pohlmann Lutz; Schlossarek Saskia; Starbatty Jutta; Yeh Yung-Hsin; Nattel Stanley; Dobrev Dobromir; Eschenhagen Thomas; Carrier Lucie
Decreased phosphorylation levels of cardiac myosin-binding protein-C in human and experimental heart failure.
Journal of molecular and cellular cardiology 2007;43(2):223-9.
2007: Abi-Char Joëlle; Maguy Ange; Coulombe Alain; Balse Elise; Ratajczak Philippe; Samuel Jane-Lise; Nattel Stanley; Hatem Stéphane N
Membrane cholesterol modulates Kv1.5 potassium channel distribution and function in rat cardiomyocytes.
The Journal of physiology 2007;582(Pt 3):1205-17.
2007: Ehrlich Joachim R; Nattel Stanley; Hohnloser Stefan H
Novel anti-arrhythmic drugs for atrial fibrillation management.
Current vascular pharmacology 2007;5(3):185-95.
2007: Gaborit Nathalie; Le Bouter Sabrina; Szuts Viktoria; Varro Andras; Escande Denis; Nattel Stanley; Demolombe Sophie
Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart.
The Journal of physiology 2007;582(Pt 2):675-93.
2007: Nattel Stanley
The heart on a chip: the role of realistic mathematical models of cardiac electrical activity in understanding and treating cardiac arrhythmias.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(6):779-80.
2007: Yeh Yung-Hsin; Ehrlich Joachim R; Qi Xiaoyan; Hébert Terence E; Chartier Denis; Nattel Stanley
Adrenergic control of a constitutively active acetylcholine-regulated potassium current in canine atrial cardiomyocytes.
Cardiovascular research 2007;74(3):406-15.
2007: Li Danshi; Nattel Stanley
Pharmacological elimination of motion artifacts during optical imaging of cardiac tissues: is blebbistatin the answer?
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(5):627-8.
2007: Nattel Stanley; Maguy Ange; Le Bouter Sabrina; Yeh Yung-Hsin
Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation.
Physiological reviews 2007;87(2):425-56.
2007: Rivard Lena; Sinno Hani; Shiroshita-Takeshita Akiko; Schram Gernot; Leung Tack-Ki; Nattel Stanley
The pharmacological response of ischemia-related atrial fibrillation in dogs: evidence for substrate-specific efficacy.
Cardiovascular research 2007;74(1):104-13.
2007: Shiroshita-Takeshita Akiko; Brundel Bianca J J M; Burstein Brett; Leung Tack-Ki; Mitamura Hideo; Ogawa Satoshi; Nattel Stanley
Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure.
Cardiovascular research 2007;74(1):75-84.
2007: Nattel Stanley; Comtois Philippe
Teasing out circadian variability in heart rate turbulence: A new approach to detecting biorhythms underlying cardiac function.
Heart rhythm : the official journal of the Heart Rhythm Society 2007;4(3):301-3.
2007: Cardin Sophie; Libby Eric; Pelletier Patricia; Le Bouter Sabrina; Shiroshita-Takeshita Akiko; Le Meur Nolwenn; Léger Jean; Demolombe Sophie; Ponton André; Glass Leon; Nattel Stanley
Contrasting gene expression profiles in two canine models of atrial fibrillation.
Circulation research 2007;100(3):425-33.
2007: Shiroshita-Takeshita Akiko; Sakabe Masao; Haugan Ketil; Hennan James K; Nattel Stanley
Model-dependent effects of the gap junction conduction-enhancing antiarrhythmic peptide rotigaptide (ZP123) on experimental atrial fibrillation in dogs.
Circulation 2007;115(3):310-8.
2007: Mustapha Zenab; Pang Li; Nattel Stanley
Characterization of the cardiac KCNE1 gene promoter.
Cardiovascular research 2007;73(1):82-91.
2006: Nattel Stanley; Carlsson Leif
Innovative approaches to anti-arrhythmic drug therapy.
Nature reviews. Drug discovery 2006;5(12):1034-49.
2006: Brundel Bianca J J M; Shiroshita-Takeshita Akiko; Qi Xiaoyan; Yeh Yung-Hsin; Chartier Denis; van Gelder Isabelle C; Henning Robert H; Kampinga Harm H; Nattel Stanley
Induction of heat shock response protects the heart against atrial fibrillation.
Circulation research 2006;99(12):1394-402.
2006: Nattel Stanley
Preoperative atrial cardiomyocyte ionic currents and postoperative AF: important insights into what is not the mechanism.
Journal of cardiovascular electrophysiology 2006;17(11):1239-41.
2006: Ehrlich Joachim R; Hoche Christin; Coutu Pierre; Metz-Weidmann Christiane; Dittrich Werner; Hohnloser Stefan H; Nattel Stanley; Gögelein Heinz
Properties of a time-dependent potassium current in pig atrium: evidence for a role of kv1.5 in repolarization.
The Journal of pharmacology and experimental therapeutics 2006;319(2):898-906.
2006: Coutu Pierre; Chartier Denis; Nattel Stanley
Comparison of Ca2+-handling properties of canine pulmonary vein and left atrial cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2006;291(5):H2290-300.
2006: Nattel Stanley
Inappropriate sinus tachycardia and beta-receptor autoantibodies: a mechanistic breakthrough?
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(10):1187-8.
2006: White Donald E; Coutu Pierre; Shi Yan-Fen; Tardif Jean-Claude; Nattel Stanley; St Arnaud René; Dedhar Shoukat; Muller William J
Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure.
Genes & development 2006;20(17):2355-60.
2006: Han Wei; Nattel Stanley; Noguchi Tomohiro; Shrier Alvin
C-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2.
The Journal of biological chemistry 2006;281(37):27134-44.
2006: Xiao Ling; Zhang Liming; Han Wei; Wang Zhiguo; Nattel Stanley
Sex-based transmural differences in cardiac repolarization and ionic-current properties in canine left ventricles.
American journal of physiology. Heart and circulatory physiology 2006;291(2):H570-80.
2006: Nattel Stanley
Ventricular tachyarrhythmia induction by strong cardiac shocks: can understanding underlying mechanisms lead to improved prevention of defibrillator failure?
Heart rhythm : the official journal of the Heart Rhythm Society 2006;3(5):596-7.
2006: Cha Tae-Joon; Ehrlich Joachim R; Chartier Denis; Qi Xiao-Yan; Xiao Ling; Nattel Stanley
Kir3-based inward rectifier potassium current: potential role in atrial tachycardia remodeling effects on atrial repolarization and arrhythmias.
Circulation 2006;113(14):1730-7.
2006: Maguy Ange; Hebert Terence E; Nattel Stanley
Involvement of lipid rafts and caveolae in cardiac ion channel function.
Cardiovascular research 2006;69(4):798-807.
2006: Shiroshita-Takeshita Akiko; Brundel Bianca J J M; Lavoie Joel; Nattel Stanley
Prednisone prevents atrial fibrillation promotion by atrial tachycardia remodeling in dogs.
Cardiovascular research 2006;69(4):865-75.
2006: Ehrlich Joachim R; Hohnloser Stefan H; Nattel Stanley
Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence.
European heart journal 2006;27(5):512-8.
2006: Tsuji Yukiomi; Zicha Stephen; Qi Xiao-Yan; Kodama Itsuo; Nattel Stanley
Potassium channel subunit remodeling in rabbits exposed to long-term bradycardia or tachycardia: discrete arrhythmogenic consequences related to differential delayed-rectifier changes.
Circulation 2006;113(3):345-55.
2006: Nattel Stanley; Opie Lionel H
Controversies in atrial fibrillation.
Lancet 2006;367(9506):262-72.
2006: Carlsson Leif; Chartier Denis; Nattel Stanley
Characterization of the in vivo and in vitro electrophysiological effects of the novel antiarrhythmic agent AZD7009 in atrial and ventricular tissue of the dog.
Journal of cardiovascular pharmacology 2006;47(1):123-32.
2006: Lamirault Guillaume; Gaborit Nathalie; Le Meur Nolwenn; Chevalier Catherine; Lande Gilles; Demolombe Sophie; Escande Denis; Nattel Stanley; Léger Jean J; Steenman Marja
Gene expression profile associated with chronic atrial fibrillation and underlying valvular heart disease in man.
Journal of molecular and cellular cardiology 2006;40(1):173-84.
2005: Nattel Stanley
Driver regions in atrial fibrillation associated with congestive heart failure: where are they, and what are they telling us?
Journal of cardiovascular electrophysiology 2005;16(12):1359-61.
2005: Nattel Stanley
Pulmonary vein cellular electrophysiology and atrial fibrillation: does basic research help us understand clinical pulmonary-vein arrhythmogenesis?
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(12):1346.
2005: Chandrasekar Baskaran; Sirois Martin G; Geoffroy Pascale; Lauzier Dominique; Nattel Stanley; Tanguay Jean-François
Local delivery of 17beta-estradiol improves reendothelialization and decreases inflammation after coronary stenting in a porcine model.
Thrombosis and haemostasis 2005;94(5):1042-7.
2005: Fang Yun; Schram Gernot; Romanenko Victor G; Shi Congzhu; Conti Lisa; Vandenberg Carol A; Davies Peter F; Nattel Stanley; Levitan Irena
Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2.
American journal of physiology. Cell physiology 2005;289(5):C1134-44.
2005: Roy Denis; Talajic Mario; Dubuc Marc; Thibault Bernard; Guerra Peter G; Macle Laurent; Gagné Pierre; Khairy Paul; Nattel Stanley
Atrial fibrillation: basic and clinical research at the Montreal Heart Institute.
The Canadian journal of cardiology 2005;21(12):1091-6.
2005: Nattel Stanley
Aldosterone antagonism and atrial fibrillation: time for clinical assessment?
European heart journal 2005;26(20):2079-80.
2005: Syed Z; Vigmond E; Nattel S; Leon L J
Atrial cell action potential parameter fitting using genetic algorithms.
Medical & biological engineering & computing 2005;43(5):561-71.
2005: Comtois Philippe; Vinet Alain; Nattel Stanley
Wave block formation in homogeneous excitable media following premature excitations: dependence on restitution relations.
Physical review. E, Statistical, nonlinear, and soft matter physics 2005;72(3 Pt 1):031919.
2005: Shiroshita-Takeshita Akiko; Brundel Bianca J J M; Nattel Stanley
Atrial fibrillation: basic mechanisms, remodeling and triggers.
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2005;13(3):181-93.
2005: Comtois P; Kneller J; Nattel S
Of circles and spirals: bridging the gap between the leading circle and spiral wave concepts of cardiac reentry.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2005;7 Suppl 2():10-20.
2005: Zou Renqiang; Kneller James; Leon L Joshua; Nattel Stanley
Substrate size as a determinant of fibrillatory activity maintenance in a mathematical model of canine atrium.
American journal of physiology. Heart and circulatory physiology 2005;289(3):H1002-12.
2005: Ehrlich Joachim R; Zicha Stephen; Coutu Pierre; Hébert Terence E; Nattel Stanley
Atrial fibrillation-associated minK38G/S polymorphism modulates delayed rectifier current and membrane localization.
Cardiovascular research 2005;67(3):520-8.
2005: Herrera Daniel; Mamarbachi Aida; Simoes Manuel; Parent Lucie; Sauvé Rémy; Wang Zhiguo; Nattel Stanley
A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels.
Molecular pharmacology 2005;68(2):305-16.
2005: Nattel Stanley
Can losartan prevent new-onset atrial fibrillation in hypertensive patients more effectively than atenolol?
Nature clinical practice. Cardiovascular medicine 2005;2(7):332-3.
2005: Nattel Stanley; Shiroshita-Takeshita Akiko; Brundel Bianca J J M; Rivard Léna
Mechanisms of atrial fibrillation: lessons from animal models.
Progress in cardiovascular diseases 2005;48(1):9-28.
2005: Gaborit Nathalie; Steenman Marja; Lamirault Guillaume; Le Meur Nolwenn; Le Bouter Sabrina; Lande Gilles; Léger Jean; Charpentier Flavien; Christ Torsten; Dobrev Dobromir; Escande Denis; Nattel Stanley; Demolombe Sophie
Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation.
Circulation 2005;112(4):471-81.
2005: Nattel Stanley
Specific potassium channel blockade for arrhythmia prevention in the ionically remodeled failing heart: peril or panacea?
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(7):739-40.
2005: Nattel Stanley
Combined parasympathetic-sympathetic nerve discharge and pulmonary vein afterdepolarizations: a new unifying concept with basic and clinical relevance.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(6):632-3.
2005: Zicha Stephen; Fernández-Velasco María; Lonardo Giuseppe; L'Heureux Nathalie; Nattel Stanley
Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model.
Cardiovascular research 2005;66(3):472-81.
2005: Pandit Sandeep V; Berenfeld Omer; Anumonwo Justus M B; Zaritski Roman M; Kneller James; Nattel Stanley; Jalife José
Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation.
Biophysical journal 2005;88(6):3806-21.
2005: Nattel Stanley
Are all sodium channel blockers created equal? Clinical-basic correlations based on observations in Brugada syndrome.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(3):261-2.
2005: Kneller James; Kalifa Jérôme; Zou Renqiang; Zaitsev Alexey V; Warren Mark; Berenfeld Omer; Vigmond Edward J; Leon L Joshua; Nattel Stanley; Jalife José
Mechanisms of atrial fibrillation termination by pure sodium channel blockade in an ionically-realistic mathematical model.
Circulation research 2005;96(5):e35-47.
2005: Nattel Stanley
Regional discrepancies in ionic currents and arrhythmia susceptibility: clinical relevance.
Heart rhythm : the official journal of the Heart Rhythm Society 2005;2(2):177-8.
2005: Cha Tae-Joon; Ehrlich Joachim R; Zhang Liming; Chartier Denis; Leung Tack Ki; Nattel Stanley
Atrial tachycardia remodeling of pulmonary vein cardiomyocytes: comparison with left atrium and potential relation to arrhythmogenesis.
Circulation 2005;111(6):728-35.
2005: Nattel Stanley; Schott Jean-Jacques
Arrhythmogenic right ventricular dysplasia type 1 and mutations in transforming growth factor beta3 gene regulatory regions: a breakthrough?
Cardiovascular research 2005;65(2):302-4.
2005: Melnyk Peter; Ehrlich Joachim R; Pourrier Marc; Villeneuve Louis; Cha Tae-Joon; Nattel Stanley
Comparison of ion channel distribution and expression in cardiomyocytes of canine pulmonary veins versus left atrium.
Cardiovascular research 2005;65(1):104-16.
2005: Nattel Stanley; Shiroshita-Takeshita Akiko; Cardin Sophie; Pelletier Patricia
Mechanisms of atrial remodeling and clinical relevance.
Current opinion in cardiology 2005;20(1):21-5.
2005: Hesketh John Christian; Herrera Daniel; Zicha Stephen; Nattel Stanley
Novel targets for cardiac antiarrhythmic drug development.
Current pharmaceutical design 2005;11(15):1959-74.
2004: Zicha Stephen; Xiao Ling; Stafford Sara; Cha Tae Joon; Han Wei; Varro Andras; Nattel Stanley
Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts.
The Journal of physiology 2004;561(Pt 3):735-48.
2004: Pourrier Marc; Herrera Daniel; Caballero Ricardo; Schram Gernot; Wang Zhiguo; Nattel Stanley
The Kv4.2 N-terminal restores fast inactivation and confers KChlP2 modulatory effects on N-terminal-deleted Kv1.4 channels.
Pflügers Archiv : European journal of physiology 2004;449(3):235-47.
2004: Li Gui-Rong; Lau Chu-Pak; Leung Tack-Ki; Nattel Stanley
Ionic current abnormalities associated with prolonged action potentials in cardiomyocytes from diseased human right ventricles.
Heart rhythm : the official journal of the Heart Rhythm Society 2004;1(4):460-8.
2004: Nattel Stanley
Age, gender, and supraventricular arrhythmias: roles of ion channels, connexins, and tissue architecture?
Heart rhythm : the official journal of the Heart Rhythm Society 2004;1(4):397-8.
2004: Shiroshita-Takeshita Akiko; Schram Gernot; Lavoie Joel; Nattel Stanley
Effect of simvastatin and antioxidant vitamins on atrial fibrillation promotion by atrial-tachycardia remodeling in dogs.
Circulation 2004;110(16):2313-9.
2004: Vigmond Edward J; Tsoi Vincent; Kuo Samuel; Arevalo Hermenigeld; Kneller James; Nattel Stanley; Trayanova Natalia
The effect of vagally induced dispersion of action potential duration on atrial arrhythmogenesis.
Heart rhythm : the official journal of the Heart Rhythm Society 2004;1(3):334-44.
2004: Nattel Stanley
Antiarrhythmic drugs for atrial fibrillation: Do we need better use, better drugs or a randomized trial of ablation as primary therapy?
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2004;171(7):752-3.
2004: Cha Tae-Joon; Ehrlich Joachim R; Zhang Liming; Nattel Stanley
Atrial ionic remodeling induced by atrial tachycardia in the presence of congestive heart failure.
Circulation 2004;110(12):1520-6.
2004: Nattel Stanley
Is atrial remodeling a viable target for prevention of atrial fibrillation recurrence?
Journal of cardiovascular electrophysiology 2004;15(8):885-6.
2004: Schram Gernot; Zhang Liming; Derakhchan Katayoun; Ehrlich Joachim R; Belardinelli Luiz; Nattel Stanley
Ranolazine: ion-channel-blocking actions and in vivo electrophysiological effects.
British journal of pharmacology 2004;142(8):1300-8.
2004: Hanna Nessrine; Cardin Sophie; Leung Tack-Ki; Nattel Stanley
Differences in atrial versus ventricular remodeling in dogs with ventricular tachypacing-induced congestive heart failure.
Cardiovascular research 2004;63(2):236-44.
2004: Nattel Stanley
The clinical relevance of connexin gating: how to control communication in the heart.
Heart rhythm : the official journal of the Heart Rhythm Society 2004;1(2):234.
2004: Zicha Stephen; Maltsev Victor A; Nattel Stanley; Sabbah Hani N; Undrovinas Albertas I
Post-transcriptional alterations in the expression of cardiac Na+ channel subunits in chronic heart failure.
Journal of molecular and cellular cardiology 2004;37(1):91-100.
2004: Nattel Stanley
Defining "culprit mechanisms" in arrhythmogenic cardiac remodeling.
Circulation research 2004;94(11):1403-5.
2004: Ehrlich Joachim R; Cha Tae-Joon; Zhang Liming; Chartier Denis; Villeneuve Louis; Hébert Terence E; Nattel Stanley
Characterization of a hyperpolarization-activated time-dependent potassium current in canine cardiomyocytes from pulmonary vein myocardial sleeves and left atrium.
The Journal of physiology 2004;557(Pt 2):583-97.
2004: Pourrier Marc; Nattel Stanley
[Anchoring proteins and cardiac sudden death: how and why?]
Médecine sciences : M/S 2004;20(4):437-41.
2004: Wang Jingxiong; Wang Huizhen; Zhang Yiqiang; Gao Huanhuan; Nattel Stanley; Wang Zhiguo
Impairment of HERG K(+) channel function by tumor necrosis factor-alpha: role of reactive oxygen species as a mediator.
The Journal of biological chemistry 2004;279(14):13289-92.
2004: Liu Gong Xin; Zhou Jun; Nattel Stanley; Koren Gideon
Single-channel recordings of a rapid delayed rectifier current in adult mouse ventricular myocytes: basic properties and effects of divalent cations.
The Journal of physiology 2004;556(Pt 2):401-13.
2004: Nakashima Hideko; Gerlach Uwe; Schmidt Dietmar; Nattel Stanley
In vivo electrophysiological effects of a selective slow delayed-rectifier potassium channel blocker in anesthetized dogs: potential insights into class III actions.
Cardiovascular research 2004;61(4):705-14.
2004: Wang Jingxiong; Zhang Yiqiang; Wang Huizhen; Han Hong; Nattel Stanley; Yang Baofeng; Wang Zhiguo
Potential mechanisms for the enhancement of HERG K+ channel function by phospholipid metabolites.
British journal of pharmacology 2004;141(4):586-99.
2004: Cha Tae-Joon; Ehrlich Joachim R; Zhang Liming; Shi Yan-Fen; Tardif Jean-Claude; Leung Tack Ki; Nattel Stanley
Dissociation between ionic remodeling and ability to sustain atrial fibrillation during recovery from experimental congestive heart failure.
Circulation 2004;109(3):412-8.
2004: Ehrlich Joachim R; Pourrier Marc; Weerapura Manjula; Ethier Nathalie; Marmabachi Aida M; Hébert Terence E; Nattel Stanley
KvLQT1 modulates the distribution and biophysical properties of HERG. A novel alpha-subunit interaction between delayed rectifier currents.
The Journal of biological chemistry 2004;279(2):1233-41.
2004: Shi Hong; Wang Huizhen; Li Danshi; Nattel Stanley; Wang Zhiguo
Differential alterations of receptor densities of three muscarinic acetylcholine receptor subtypes and current densities of the corresponding K+ channels in canine atria with atrial fibrillation induced by experimental congestive heart failure.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2004;14(1-2):31-40.
2003: Nattel Stanley
Basic electrophysiology of the pulmonary veins and their role in atrial fibrillation: precipitators, perpetuators, and perplexers.
Journal of cardiovascular electrophysiology 2003;14(12):1372-5.
2003: Nattel Stanley
Remodeling of cardiac inward-rectifier currents: an often-overlooked contributor to arrhythmogenic states.
Journal of molecular and cellular cardiology 2003;35(12):1395-8.
2003: Khairy Paul; Thibault Bernard; Talajic Mario; Dubuc Marc; Roy Denis; Guerra Peter G; Nattel Stanley
Prognostic significance of ventricular arrhythmias post-myocardial infarction.
The Canadian journal of cardiology 2003;19(12):1393-404.
2003: Cardin Sophie; Li Danshi; Thorin-Trescases Nathalie; Leung Tack-Ki; Thorin Eric; Nattel Stanley
Evolution of the atrial fibrillation substrate in experimental congestive heart failure: angiotensin-dependent and -independent pathways.
Cardiovascular research 2003;60(2):315-25.
2003: Nattel Stanley; Kneller James; Zou Renqiang; Leon L Joshua
Mechanisms of termination of atrial fibrillation by Class I antiarrhythmic drugs: evidence from clinical, experimental, and mathematical modeling studies.
Journal of cardiovascular electrophysiology 2003;14(10 Suppl):S133-9.
2003: Zicha Stephen; Moss Isaac; Allen Bruce; Varro Andras; Papp Julius; Dumaine Robert; Antzelevich Charles; Nattel Stanley
Molecular basis of species-specific expression of repolarizing K+ currents in the heart.
American journal of physiology. Heart and circulatory physiology 2003;285(4):H1641-9.
2003: Nattel Stanley; Lumer Gerald; Talajic Mario; Roy Denis
Cost evaluation of rhythm control methods for atrial fibrillation: evidence from CTAF.
Cardiac electrophysiology review 2003;7(3):211-4.
2003: Guerra Peter G; Thibault Bernard; Dubuc Marc; Talajic Mario; Roy Denis; Crépeau Jacques; Nattel Stanley; Tardif Jean-Claude
Identification of atrial tissue in pulmonary veins using intravascular ultrasound.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2003;16(9):982-7.
2003: Ehrlich Joachim R; Cha Tae-Joon; Zhang Liming; Chartier Denis; Melnyk Peter; Hohnloser Stefan H; Nattel Stanley
Cellular electrophysiology of canine pulmonary vein cardiomyocytes: action potential and ionic current properties.
The Journal of physiology 2003;551(Pt 3):801-13.
2003: Pourrier M; Schram G; Nattel S
Properties, expression and potential roles of cardiac K+ channel accessory subunits: MinK, MiRPs, KChIP, and KChAP.
The Journal of membrane biology 2003;194(3):141-52.
2003: Schram Gernot; Pourrier Marc; Wang Zhiguo; White Michel; Nattel Stanley
Barium block of Kir2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents.
Cardiovascular research 2003;59(2):328-38.
2003: Kalifa Jérôme; Jalife José; Zaitsev Alexey V; Bagwe Suveer; Warren Mark; Moreno Javier; Berenfeld Omer; Nattel Stanley
Intra-atrial pressure increases rate and organization of waves emanating from the superior pulmonary veins during atrial fibrillation.
Circulation 2003;108(6):668-71.
2003: Pourrier Marc; Zicha Stephen; Ehrlich Joachim; Han Wei; Nattel Stanley
Canine ventricular KCNE2 expression resides predominantly in Purkinje fibers.
Circulation research 2003;93(3):189-91.
2003: Pang Li; Koren Gideon; Wang Zhiguo; Nattel Stanley
Tissue-specific expression of two human Ca(v)1.2 isoforms under the control of distinct 5' flanking regulatory elements.
FEBS letters 2003;546(2-3):349-54.
2003: Nattel Stanley
Atrial electrophysiology and mechanisms of atrial fibrillation.
Journal of cardiovascular pharmacology and therapeutics 2003;8 Suppl 1():S5-11.
2003: Caballero Ricardo; Pourrier Marc; Schram Gernot; Delpón Eva; Tamargo Juan; Nattel Stanley
Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines.
British journal of pharmacology 2003;138(8):1475-84.
2003: Sinno Hani; Derakhchan Katayoun; Libersan Danielle; Merhi Yahye; Leung Tack Ki; Nattel Stanley
Atrial ischemia promotes atrial fibrillation in dogs.
Circulation 2003;107(14):1930-6.
2003: Shinagawa Kaori; Derakhchan Katayoun; Nattel Stanley
Pharmacological prevention of atrial tachycardia induced atrial remodeling as a potential therapeutic strategy.
Pacing and clinical electrophysiology : PACE 2003;26(3):752-64.
2003: Shinagawa Kaori; Shiroshita-Takeshita Akiko; Schram Gernot; Nattel Stanley
Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium: insights into the mechanism of the superior efficacy of amiodarone.
Circulation 2003;107(10):1440-6.
2003: Nattel Stanley
Rhythm versus rate control for atrial fibrillation management: what recent randomized clinical trials allow us to affirm.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2003;168(5):572-3.
2003: Nattel Stanley
Human genetics: Lost anchors cost lives.
Nature 2003;421(6923):587, 589-90.
2003: Nattel Stanley
Drugs to promote sinus rhythm reversion and maintenance in atrial fibrillation--why amiodarone is better.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2003;17(1):5-6.
2003: Zhang Yiqiang; Wang Huizhen; Wang Jingxiong; Han Hong; Nattel Stanley; Wang Zhiguo
Normal function of HERG K+ channels expressed in HEK293 cells requires basal protein kinase B activity.
FEBS letters 2003;534(1-3):125-32.
2002: Han Wei; Zhang Liming; Schram Gernot; Nattel Stanley
Properties of potassium currents in Purkinje cells of failing human hearts.
American journal of physiology. Heart and circulatory physiology 2002;283(6):H2495-503.
2002: Jørgensen Peter; Schäfer Carsten; Guerra Peter G; Talajic Mario; Nattel Stanley; Glass Leon
A mathematical model of human atrioventricular nodal function incorporating concealed conduction.
Bulletin of mathematical biology 2002;64(6):1083-99.
2002: Han Wei; Bao Weisheng; Wang Zhiguo; Nattel Stanley
Comparison of ion-channel subunit expression in canine cardiac Purkinje fibers and ventricular muscle.
Circulation research 2002;91(9):790-7.
2002: Khairy Paul; Nattel Stanley
New insights into the mechanisms and management of atrial fibrillation.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2002;167(9):1012-20.
2002: Schram Gernot; Melnyk Peter; Pourrier Marc; Wang Zhiguo; Nattel Stanley
Kir2.4 and Kir2.1 K(+) channel subunits co-assemble: a potential new contributor to inward rectifier current heterogeneity.
The Journal of physiology 2002;544(Pt 2):337-49.
2002: Wang Huizhen; Zhang Yiqiang; Cao Liwen; Han Hong; Wang Jingxiong; Yang Baofeng; Nattel Stanley; Wang Zhiguo
HERG K+ channel, a regulator of tumor cell apoptosis and proliferation.
Cancer research 2002;62(17):4843-8.
2002: Melnyk Peter; Zhang Liming; Shrier Alvin; Nattel Stanley
Differential distribution of Kir2.1 and Kir2.3 subunits in canine atrium and ventricle.
American journal of physiology. Heart and circulatory physiology 2002;283(3):H1123-33.
2002: Li Gui-Rong; Lau Chu-Pak; Ducharme Anique; Tardif Jean-Claude; Nattel Stanley
Transmural action potential and ionic current remodeling in ventricles of failing canine hearts.
American journal of physiology. Heart and circulatory physiology 2002;283(3):H1031-41.
2002: Lumer G B; Roy D; Talajic M; Couturier A; Lambert J; Frasure-Smith N; Thibault B; Dubuc M; Gagné P; Nattel S
Amiodarone reduces procedures and costs related to atrial fibrillation in a controlled clinical trial.
European heart journal 2002;23(13):1050-6.
2002: Shinagawa Kaori; Shi Yan-Fen; Tardif Jean-Claude; Leung Tack-Ki; Nattel Stanley
Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs.
Circulation 2002;105(22):2672-8.
2002: Shi Yanfen; Li Danshi; Tardif Jean-Claude; Nattel Stanley
Enalapril effects on atrial remodeling and atrial fibrillation in experimental congestive heart failure.
Cardiovascular research 2002;54(2):456-61.
2002: Shinagawa Kaori; Mitamura Hideo; Ogawa Satoshi; Nattel Stanley
Effects of inhibiting Na(+)/H(+)-exchange or angiotensin converting enzyme on atrial tachycardia-induced remodeling.
Cardiovascular research 2002;54(2):438-46.
2002: Kneller James; Sun Hui; Leblanc Normand; Nattel Stanley
Remodeling of Ca(2+)-handling by atrial tachycardia: evidence for a role in loss of rate-adaptation.
Cardiovascular research 2002;54(2):416-26.
2002: Nattel Stanley
Therapeutic implications of atrial fibrillation mechanisms: can mechanistic insights be used to improve AF management?
Cardiovascular research 2002;54(2):347-60.
2002: Bosch Ralph F; Nattel Stanley
Cellular electrophysiology of atrial fibrillation.
Cardiovascular research 2002;54(2):259-69.
2002: Nattel Stanley; Allessie Maurits; Haissaguerre Michel
Spotlight on atrial fibrillation-the 'complete arrhythmia'.
Cardiovascular research 2002;54(2):197-203.
2002: Kneller James; Zou Renqiang; Vigmond Edward J; Wang Zhiguo; Leon L Joshua; Nattel Stanley
Cholinergic atrial fibrillation in a computer model of a two-dimensional sheet of canine atrial cells with realistic ionic properties.
Circulation research 2002;90(9):E73-87.
2002: Schram Gernot; Pourrier Marc; Melnyk Peter; Nattel Stanley
Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function.
Circulation research 2002;90(9):939-50.
2002: Ehrlich Joachim R; Nattel Stanley; Hohnloser Stefan H
Atrial fibrillation and congestive heart failure: specific considerations at the intersection of two common and important cardiac disease sets.
Journal of cardiovascular electrophysiology 2002;13(4):399-405.
2002: Weerapura Manjula; Nattel Stanley; Chartier Denis; Caballero Ricardo; Hébert Terence E
A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link?
The Journal of physiology 2002;540(Pt 1):15-27.
2002: Kneller James; Ramirez Rafael J; Chartier Denis; Courtemanche Marc; Nattel Stanley
Time-dependent transients in an ionically based mathematical model of the canine atrial action potential.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1437-51.
2002: Zhang Li-Ming; Wang Zhiguo; Nattel Stanley
Effects of sustained beta-adrenergic stimulation on ionic currents of cultured adult guinea pig cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2002;282(3):H880-9.
2002: Weerapura Manjula; Hébert Terence E; Nattel Stanley
Dofetilide block involves interactions with open and inactivated states of HERG channels.
Pflügers Archiv : European journal of physiology 2002;443(4):520-31.
2002: Glass Leon; Nagai Yoshihiko; Hall Kevin; Talajic Mario; Nattel Stanley
Predicting the entrainment of reentrant cardiac waves using phase resetting curves.
Physical review. E, Statistical, nonlinear, and soft matter physics 2002;65(2 Pt 1):021908.
2002: Nattel Stanley
New ideas about atrial fibrillation 50 years on.
Nature 2002;415(6868):219-26.
2002: Shinagawa Kaori; Li Danshi; Leung Tack Ki; Nattel Stanley
Consequences of atrial tachycardia-induced remodeling depend on the preexisting atrial substrate.
Circulation 2002;105(2):251-7.
2002: Nattel Stanley; Khairy Paul; Roy Denis; Thibault Bernard; Guerra Peter; Talajic Mario; Dubuc Marc
New approaches to atrial fibrillation management: a critical review of a rapidly evolving field.
Drugs 2002;62(16):2377-97.
2002: Shi Hong; Wang Huizhen; Han Hong; Xu Donghui; Yang Baofeng; Nattel Stanley; Wang Zhiguo
Ultrarapid delayed rectifier K(+) current in H9c2 rat ventricular cell line: biophysical property and molecular identity.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2002;12(4):215-26.
2001: Wang J; Wang H; Han H; Zhang Y; Yang B; Nattel S; Wang Z
Phospholipid metabolite 1-palmitoyl-lysophosphatidylcholine enhances human ether-a-go-go-related gene (HERG) K(+) channel function.
Circulation 2001;104(22):2645-8.
2001: Li D; Shinagawa K; Pang L; Leung T K; Cardin S; Wang Z; Nattel S
Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure.
Circulation 2001;104(21):2608-14.
2001: Shi Y; Ducharme A; Li D; Gaspo R; Nattel S; Tardif J C
Remodeling of atrial dimensions and emptying function in canine models of atrial fibrillation.
Cardiovascular research 2001;52(2):217-25.
2001: Nattel S; Khairy P; Schram G
Arrhythmogenic ionic remodeling: adaptive responses with maladaptive consequences.
Trends in cardiovascular medicine 2001;11(7):295-301.
2001: Han W; Chartier D; Li D; Nattel S
Ionic remodeling of cardiac Purkinje cells by congestive heart failure.
Circulation 2001;104(17):2095-100.
2001: Han H; Wang H; Long H; Nattel S; Wang Z
Oxidative preconditioning and apoptosis in L-cells. Roles of protein kinase B and mitogen-activated protein kinases.
The Journal of biological chemistry 2001;276(28):26357-64.
2001: Li D; Zhang L; Kneller J; Nattel S
Potential ionic mechanism for repolarization differences between canine right and left atrium.
Circulation research 2001;88(11):1168-75.
2001: Wang H; Han H; Zhang L; Shi H; Schram G; Nattel S; Wang Z
Expression of multiple subtypes of muscarinic receptors and cellular distribution in the human heart.
Molecular pharmacology 2001;59(5):1029-36.
2001: Bénardeau A; Fareh S; Nattel S
Effects of verapamil on atrial fibrillation and its electrophysiological determinants in dogs.
Cardiovascular research 2001;50(1):85-96.
2001: Derakhchan K; Villemaire C; Talajic M; Nattel S
The class III antiarrhythmic drugs dofetilide and sotalol prevent AF induction by atrial premature complexes at doses that fail to terminate AF.
Cardiovascular research 2001;50(1):75-84.
2001: Fareh S; Bénardeau A; Nattel S
Differential efficacy of L- and T-type calcium channel blockers in preventing tachycardia-induced atrial remodeling in dogs.
Cardiovascular research 2001;49(4):762-70.
2001: Sun H; Chartier D; Leblanc N; Nattel S
Intracellular calcium changes and tachycardia-induced contractile dysfunction in canine atrial myocytes.
Cardiovascular research 2001;49(4):751-61.
2001: Han W; Wang Z; Nattel S
Slow delayed rectifier current and repolarization in canine cardiac Purkinje cells.
American journal of physiology. Heart and circulatory physiology 2001;280(3):H1075-80.
2000: Ramirez R J; Nattel S; Courtemanche M
Mathematical analysis of canine atrial action potentials: rate, regional factors, and electrical remodeling.
American journal of physiology. Heart and circulatory physiology 2000;279(4):H1767-85.
2000: Yue L; Wang Z; Rindt H; Nattel S
Molecular evidence for a role of Shaw (Kv3) potassium channel subunits in potassium currents of dog atrium.
The Journal of physiology 2000;527 Pt 3():467-78.
2000: Nattel S; Li D
Ionic remodeling in the heart: pathophysiological significance and new therapeutic opportunities for atrial fibrillation.
Circulation research 2000;87(6):440-7.
2000: Wang H; Shi H; Zhang L; Pourrier M; Yang B; Nattel S; Wang Z
Nicotine is a potent blocker of the cardiac A-type K(+) channels. Effects on cloned Kv4.3 channels and native transient outward current.
Circulation 2000;102(10):1165-71.
2000: Han W; Wang Z; Nattel S
A comparison of transient outward currents in canine cardiac Purkinje cells and ventricular myocytes.
American journal of physiology. Heart and circulatory physiology 2000;279(2):H466-74.
2000: Weerapura M; Nattel S; Courtemanche M; Doern D; Ethier N; Hebert T
State-dependent barium block of wild-type and inactivation-deficient HERG channels in Xenopus oocytes.
The Journal of physiology 2000;526 Pt 2():265-78.
2000: Li D; Bénardeau A; Nattel S
Contrasting efficacy of dofetilide in differing experimental models of atrial fibrillation.
Circulation 2000;102(1):104-12.
2000: Li D; Melnyk P; Feng J; Wang Z; Petrecca K; Shrier A; Nattel S
Effects of experimental heart failure on atrial cellular and ionic electrophysiology.
Circulation 2000;101(22):2631-8.
2000: Yue L; Feng J L; Wang Z; Nattel S
Effects of ambasilide, quinidine, flecainide and verapamil on ultra-rapid delayed rectifier potassium currents in canine atrial myocytes.
Cardiovascular research 2000;46(1):151-61.
2000: Roy D; Talajic M; Dorian P; Connolly S; Eisenberg M J; Green M; Kus T; Lambert J; Dubuc M; Gagné P; Nattel S; Thibault B
Amiodarone to prevent recurrence of atrial fibrillation. Canadian Trial of Atrial Fibrillation Investigators.
The New England journal of medicine 2000;342(13):913-20.
2000: Nattel S; Matthews C; De Blasio E; Han W; Li D; Yue L
Dose-dependence of 4-aminopyridine plasma concentrations and electrophysiological effects in dogs : potential relevance to ionic mechanisms in vivo.
Circulation 2000;101(10):1179-84.
2000: Doucet S; Malekianpour M; Théroux P; Bilodeau L; Côté G; de Guise P; Dupuis J; Joyal M; Gosselin G; Tanguay J F; Juneau M; Harel F; Nattel S; Tardif J C; Lespérance J
Randomized trial comparing intravenous nitroglycerin and heparin for treatment of unstable angina secondary to restenosis after coronary artery angioplasty.
Circulation 2000;101(9):955-61.
2000: Nattel S; Li D; Yue L
Basic mechanisms of atrial fibrillation--very new insights into very old ideas.
Annual review of physiology 2000;62():51-77.
1999: Fareh S; Bénardeau A; Thibault B; Nattel S
The T-type Ca(2+) channel blocker mibefradil prevents the development of a substrate for atrial fibrillation by tachycardia-induced atrial remodeling in dogs.
Circulation 1999;100(21):2191-7.
1999: Nattel S
Electrophysiologic remodeling: are ion channels static players or dynamic movers?
Journal of cardiovascular electrophysiology 1999;10(11):1553-6.
1999: Nattel S; Singh B N
Evolution, mechanisms, and classification of antiarrhythmic drugs: focus on class III actions.
The American journal of cardiology 1999;84(9A):11R-19R.
1999: Sun H; Chartier D; Nattel S; Leblanc N
Ca(2+)-activated Cl(-) current can be triggered by Na(+) current-induced SR Ca(2+) release in rabbit ventricle.
The American journal of physiology 1999;277(4 Pt 2):H1467-77.
1999: Bosch R F; Wang Z; Li G R; Nattel S
Electrophysiological mechanisms by which hypothyroidism delays repolarization in guinea pig hearts.
The American journal of physiology 1999;277(1 Pt 2):H211-20.
1999: Li D; Fareh S; Leung T K; Nattel S
Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort.
Circulation 1999;100(1):87-95.
1999: Courtemanche M; Ramirez R J; Nattel S
Ionic targets for drug therapy and atrial fibrillation-induced electrical remodeling: insights from a mathematical model.
Cardiovascular research 1999;42(2):477-89.
1999: Gaspo R; Sun H; Fareh S; Levi M; Yue L; Allen B G; Hebert T E; Nattel S
Dihydropyridine and beta adrenergic receptor binding in dogs with tachycardia-induced atrial fibrillation.
Cardiovascular research 1999;42(2):434-42.
1999: Nattel S
Atrial electrophysiological remodeling caused by rapid atrial activation: underlying mechanisms and clinical relevance to atrial fibrillation.
Cardiovascular research 1999;42(2):298-308.
1999: Yue L; Melnyk P; Gaspo R; Wang Z; Nattel S
Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation.
Circulation research 1999;84(7):776-84.
1999: Yue L; Feng J; Wang Z; Nattel S
Adrenergic control of the ultrarapid delayed rectifier current in canine atrial myocytes.
The Journal of physiology 1999;516 ( Pt 2)():385-98.
1999: Bosch R F; Li G R; Gaspo R; Nattel S
Electrophysiologic effects of chronic amiodarone therapy and hypothyroidism, alone and in combination, on guinea pig ventricular myocytes.
The Journal of pharmacology and experimental therapeutics 1999;289(1):156-65.
1999: Thibault B; Nattel S
Optimal management with Class I and Class III antiarrhythmic drugs should be done in the outpatient setting: protagonist.
Journal of cardiovascular electrophysiology 1999;10(3):472-81.
1999: Wang Z; Feng J; Shi H; Pond A; Nerbonne J M; Nattel S
Potential molecular basis of different physiological properties of the transient outward K+ current in rabbit and human atrial myocytes.
Circulation research 1999;84(5):551-61.
1999: Nattel S
The molecular and ionic specificity of antiarrhythmic drug actions.
Journal of cardiovascular electrophysiology 1999;10(2):272-82.
1999: Hu K; Li G R; Nattel S
Adenosine-induced activation of ATP-sensitive K+ channels in excised membrane patches is mediated by PKC.
The American journal of physiology 1999;276(2 Pt 2):H488-95.
1999: Côté G; Tardif J C; Lespérance J; Lambert J; Bourassa M; Bonan R; Gosselin G; Joyal M; Tanguay J F; Nattel S; Gallo R; Crépeau J
Effects of probucol on vascular remodeling after coronary angioplasty. Multivitamins and Protocol Study Group.
Circulation 1999;99(1):30-5.
1998: Wang Z; Yue L; White M; Pelletier G; Nattel S
Differential distribution of inward rectifier potassium channel transcripts in human atrium versus ventricle.
Circulation 1998;98(22):2422-8.
1998: Guerra P G; Talajic M; Roy D; Dubuc M; Thibault B; Nattel S
Is there a future for antiarrhythmic drug therapy?
Drugs 1998;56(5):767-81.
1998: Fareh S; Villemaire C; Nattel S
Importance of refractoriness heterogeneity in the enhanced vulnerability to atrial fibrillation induction caused by tachycardia-induced atrial electrical remodeling.
Circulation 1998;98(20):2202-9.
1998: Feng J; Xu D; Wang Z; Nattel S
Ultrarapid delayed rectifier current inactivation in human atrial myocytes: properties and consequences.
The American journal of physiology 1998;275(5 Pt 2):H1717-25.
1998: Feng J; Yue L; Wang Z; Nattel S
Ionic mechanisms of regional action potential heterogeneity in the canine right atrium.
Circulation research 1998;83(5):541-51.
1998: Sun H; Gaspo R; Leblanc N; Nattel S
Cellular mechanisms of atrial contractile dysfunction caused by sustained atrial tachycardia.
Circulation 1998;98(7):719-27.
1998: Courtemanche M; Ramirez R J; Nattel S
Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model.
The American journal of physiology 1998;275(1 Pt 2):H301-21.
1998: Lu Y; Yue L; Wang Z; Nattel S
Effects of the diuretic agent indapamide on Na+, transient outward, and delayed rectifier currents in canine atrial myocytes.
Circulation research 1998;83(2):158-66.
1998: Bosch R F; Gaspo R; Busch A E; Lang H J; Li G R; Nattel S
Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes.
Cardiovascular research 1998;38(2):441-50.
1998: Nattel S
Experimental evidence for proarrhythmic mechanisms of antiarrhythmic drugs.
Cardiovascular research 1998;37(3):567-77.
1998: Li G R; Sun H; Nattel S
Characterization of a transient outward K+ current with inward rectification in canine ventricular myocytes.
The American journal of physiology 1998;274(3 Pt 1):C577-85.
1997: Gaspo R; Bosch R F; Talajic M; Nattel S
Functional mechanisms underlying tachycardia-induced sustained atrial fibrillation in a chronic dog model.
Circulation 1997;96(11):4027-35.
1997: Gaspo R; Bosch R F; Bou-Abboud E; Nattel S
Tachycardia-induced changes in Na+ current in a chronic dog model of atrial fibrillation.
Circulation research 1997;81(6):1045-52.
1997: Yue L; Feng J; Gaspo R; Li G R; Wang Z; Nattel S
Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation.
Circulation research 1997;81(4):512-25.
1997: Roy D; Talajic M; Thibault B; Dubuc M; Nattel S; Eisenberg M J; Ciampi A
Pilot study and protocol of the Canadian Trial of Atrial Fibrillation (CTAF).
The American journal of cardiology 1997;80(4):464-8.
1997: Liu L; Nattel S
Differing sympathetic and vagal effects on atrial fibrillation in dogs: role of refractoriness heterogeneity.
The American journal of physiology 1997;273(2 Pt 2):H805-16.
1997: Tardif J C; Cöté G; Lespérance J; Bourassa M; Lambert J; Doucet S; Bilodeau L; Nattel S; de Guise P
Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group.
The New England journal of medicine 1997;337(6):365-72.
1997: Sun H; Leblanc N; Nattel S
Mechanisms of inactivation of L-type calcium channels in human atrial myocytes.
The American journal of physiology 1997;272(4 Pt 2):H1625-35.
1997: Feng J; Wible B; Li G R; Wang Z; Nattel S
Antisense oligodeoxynucleotides directed against Kv1.5 mRNA specifically inhibit ultrarapid delayed rectifier K+ current in cultured adult human atrial myocytes.
Circulation research 1997;80(4):572-9.
1997: Nattel S; Bourne G; Talajic M
Insights into mechanisms of antiarrhythmic drug action from experimental models of atrial fibrillation.
Journal of cardiovascular electrophysiology 1997;8(4):469-80.
1997: Feng J; Wang Z; Li G R; Nattel S
Effects of class III antiarrhythmic drugs on transient outward and ultra-rapid delayed rectifier currents in human atrial myocytes.
The Journal of pharmacology and experimental therapeutics 1997;281(1):384-92.
1997: Li G R; Nattel S
Properties of human atrial ICa at physiological temperatures and relevance to action potential.
The American journal of physiology 1997;272(1 Pt 2):H227-35.
1997: Duan D; Hume J R; Nattel S
Evidence that outwardly rectifying Cl- channels underlie volume-regulated Cl- currents in heart.
Circulation research 1997;80(1):103-13.
1996: Yue L; Feng J; Li G R; Nattel S
Characterization of an ultrarapid delayed rectifier potassium channel involved in canine atrial repolarization.
The Journal of physiology 1996;496 ( Pt 3)():647-62.
1996: Bou-Abboud E; Nattel S
Relative role of alkalosis and sodium ions in reversal of class I antiarrhythmic drug-induced sodium channel blockade by sodium bicarbonate.
Circulation 1996;94(8):1954-61.
1996: Wang J; Liu L; Feng J; Nattel S
Regional and functional factors determining induction and maintenance of atrial fibrillation in dogs.
The American journal of physiology 1996;271(1 Pt 2):H148-58.
1996: Yue L; Feng J; Li G R; Nattel S
Transient outward and delayed rectifier currents in canine atrium: properties and role of isolation methods.
The American journal of physiology 1996;270(6 Pt 2):H2157-68.
1996: Feng J; Li G R; Fermini B; Nattel S
Properties of sodium and potassium currents of cultured adult human atrial myocytes.
The American journal of physiology 1996;270(5 Pt 2):H1676-86.
1996: Li G R; Feng J; Wang Z; Fermini B; Nattel S
Adrenergic modulation of ultrarapid delayed rectifier K+ current in human atrial myocytes.
Circulation research 1996;78(5):903-15.
1996: Li G R; Nattel S
Demonstration of an inward Na(+)-Ca2+ exchange current in adult human atrial myocytes.
Annals of the New York Academy of Sciences 1996;779():525-8.
1996: Li G R; Feng J; Yue L; Carrier M; Nattel S
Evidence for two components of delayed rectifier K+ current in human ventricular myocytes.
Circulation research 1996;78(4):689-96.
1996: Hu K; Duan D; Li G R; Nattel S
Protein kinase C activates ATP-sensitive K+ current in human and rabbit ventricular myocytes.
Circulation research 1996;78(3):492-8.
1996: Li G R; Feng J; Wang Z; Nattel S
Transmembrane chloride currents in human atrial myocytes.
The American journal of physiology 1996;270(2 Pt 1):C500-7.
1995: Nattel S
Newer developments in the management of atrial fibrillation.
American heart journal 1995;130(5):1094-106.
1995: Hu K; Nattel S
Mechanisms of ischemic preconditioning in rat hearts. Involvement of alpha 1B-adrenoceptors, pertussis toxin-sensitive G proteins, and protein kinase C.
Circulation 1995;92(8):2259-65.
1995: Ranger S; Nattel S
Determinants and mechanisms of flecainide-induced promotion of ventricular tachycardia in anesthetized dogs.
Circulation 1995;92(5):1300-11.
1995: Li G R; Feng J; Wang Z; Fermini B; Nattel S
Comparative mechanisms of 4-aminopyridine-resistant Ito in human and rabbit atrial myocytes.
The American journal of physiology 1995;269(2 Pt 2):H463-72.
1995: Duan D; Fermini B; Nattel S
Alpha-adrenergic control of volume-regulated Cl- currents in rabbit atrial myocytes. Characterization of a novel ionic regulatory mechanism.
Circulation research 1995;77(2):379-93.
1995: Wang Z; Feng J; Nattel S
Idiopathic atrial fibrillation in dogs: electrophysiologic determinants and mechanisms of antiarrhythmic action of flecainide.
Journal of the American College of Cardiology 1995;26(1):277-86.
1995: Wang Z; Fermini B; Feng J; Nattel S
Role of chloride currents in repolarizing rabbit atrial myocytes.
The American journal of physiology 1995;268(5 Pt 2):H1992-2002.
1995: Li G R; Feng J; Shrier A; Nattel S
Contribution of ATP-sensitive potassium channels to the electrophysiological effects of adenosine in guinea-pig atrial cells.
The Journal of physiology 1995;484 ( Pt 3)():629-42.
1995: Wang Z; Fermini B; Nattel S
Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes.
The Journal of pharmacology and experimental therapeutics 1995;272(1):184-96.
1994: Wang Z; Fermini B; Nattel S
Rapid and slow components of delayed rectifier current in human atrial myocytes.
Cardiovascular research 1994;28(10):1540-6.
1994: Wang J; Feng J; Nattel S
Class III antiarrhythmic drug action in experimental atrial fibrillation. Differences in reverse use dependence and effectiveness between d-sotalol and the new antiarrhythmic drug ambasilide.
Circulation 1994;90(4):2032-40.
1994: Duan D; Nattel S
Properties of single outwardly rectifying Cl- channels in heart.
Circulation research 1994;75(4):789-95.
1994: Nattel S; Hadjis T; Talajic M
The treatment of atrial fibrillation. An evaluation of drug therapy, electrical modalities and therapeutic considerations.
Drugs 1994;48(3):345-71.
1994: Villemaire C; Nattel S
Modulation of procainamide's effect on cardiac conduction in dogs by extracellular potassium concentration. A quantitative analysis.
Circulation 1994;89(6):2870-8.
1994: Fermini B; Nattel S
Choline chloride activates time-dependent and time-independent K+ currents in dog atrial myocytes.
The American journal of physiology 1994;266(1 Pt 1):C42-51.
1994: Nattel S; Talajic M; Beaudoin D; Matthews C; Roy D
Absence of pharmacokinetic interaction between amiodarone and lidocaine.
The American journal of cardiology 1994;73(1):92-4.
1994: Billette J; Nattel S
Dynamic behavior of the atrioventricular node: a functional model of interaction between recovery, facilitation, and fatigue.
Journal of cardiovascular electrophysiology 1994;5(1):90-102.
1993: Nayebpour M; Billette J; Amellal F; Nattel S
Effects of adenosine on rate-dependent atrioventricular nodal function. Potential roles in tachycardia termination and physiological regulation.
Circulation 1993;88(6):2632-45.
1993: Wang Z; Fermini B; Nattel S
Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents.
Circulation research 1993;73(6):1061-76.
1993: Wang Z; Fermini B; Nattel S
Mechanism of flecainide's rate-dependent actions on action potential duration in canine atrial tissue.
The Journal of pharmacology and experimental therapeutics 1993;267(2):575-81.
1993: Nattel S
Comparative mechanisms of action of antiarrhythmic drugs.
The American journal of cardiology 1993;72(16):13F-17F.
1993: Arenal A; Villemaire C; Nattel S
Mechanism of selective epicardial activation delay during acute myocardial ischemia in dogs.
Circulation 1993;88(5 Pt 1):2381-8.
1993: O'Hara G; Gendreau R; Billette J; Amellal F; Nayebpour M; Talajic M; Nattel S
Rate-dependent functional properties of retrograde atrioventricular nodal conduction in experimental animals.
The American journal of physiology 1993;265(4 Pt 2):H1257-64.
1993: Wang J; Bourne G W; Wang Z; Villemaire C; Talajic M; Nattel S
Comparative mechanisms of antiarrhythmic drug action in experimental atrial fibrillation. Importance of use-dependent effects on refractoriness.
Circulation 1993;88(3):1030-44.
1993: Wang Z; Fermini B; Nattel S
Delayed rectifier outward current and repolarization in human atrial myocytes.
Circulation research 1993;73(2):276-85.
1993: Duan D; Fermini B; Nattel S
Potassium channel blocking properties of propafenone in rabbit atrial myocytes.
The Journal of pharmacology and experimental therapeutics 1993;264(3):1113-23.
1993: Ranger S; Sheldon R; Fermini B; Nattel S
Modulation of flecainide's cardiac sodium channel blocking actions by extracellular sodium: a possible cellular mechanism for the action of sodium salts in flecainide cardiotoxicity.
The Journal of pharmacology and experimental therapeutics 1993;264(3):1160-7.
1993: Nattel S; Arenal A
Antiarrhythmic prophylaxis after acute myocardial infarction. Is lidocaine still useful?
Drugs 1993;45(1):9-14.
1992: Duan D Y; Fermini B; Nattel S
Sustained outward current observed after I(to1) inactivation in rabbit atrial myocytes is a novel Cl- current.
The American journal of physiology 1992;263(6 Pt 2):H1967-71.
1992: Fermini B; Wang Z; Duan D; Nattel S
Differences in rate dependence of transient outward current in rabbit and human atrium.
The American journal of physiology 1992;263(6 Pt 2):H1747-54.
1992: Talajic M; Lemery R; Roy D; Villemaire C; Cartier R; Coutu B; Nattel S
Rate-dependent effects of diltiazem on human atrioventricular nodal properties.
Circulation 1992;86(3):870-7.
1992: Wang Z; Pagé P; Nattel S
Mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation.
Circulation research 1992;71(2):271-87.
1992: Villemaire C; Savard P; Talajic M; Nattel S
A quantitative analysis of use-dependent ventricular conduction slowing by procainamide in anesthetized dogs.
Circulation 1992;85(6):2255-66.
1992: O'Hara G; Villemaire C; Talajic M; Nattel S
Effects of flecainide on the rate dependence of atrial refractoriness, atrial repolarization and atrioventricular node conduction in anesthetized dogs.
Journal of the American College of Cardiology 1992;19(6):1335-42.
1992: Nayebpour M; Talajic M; Nattel S
Effects of beta-adrenergic receptor stimulation and blockade on rate-dependent atrioventricular nodal properties.
Circulation research 1992;70(5):902-11.
1991: Nattel S; Turmel N; Macleod R; Solymoss B C
Actions of intravenous magnesium on ventricular arrhythmias caused by acute myocardial infarction.
The Journal of pharmacology and experimental therapeutics 1991;259(2):939-46.
1991: Nayebpour M; Talajic M; Nattel S
Quantitation of dynamic AV nodal properties and application to predict rate-dependent AV conduction.
The American journal of physiology 1991;261(2 Pt 2):H292-300.
1991: Ranger S; Talajic M; Lemery R; Roy D; Villemaire C; Nattel S
Kinetics of use-dependent ventricular conduction slowing by antiarrhythmic drugs in humans.
Circulation 1991;83(6):1987-94.
1991: Wang Z G; Fermini B; Nattel S
Repolarization differences between guinea pig atrial endocardium and epicardium: evidence for a role of Ito.
The American journal of physiology 1991;260(5 Pt 2):H1501-6.
1991: Talajic M; Papadatos D; Villemaire C; Glass L; Nattel S
A unified model of atrioventricular nodal conduction predicts dynamic changes in Wenckebach periodicity.
Circulation research 1991;68(5):1280-93.
1991: Nattel S
Antiarrhythmic drug classifications. A critical appraisal of their history, present status, and clinical relevance.
Drugs 1991;41(5):672-701.
1991: Muller T; Roy D; Talajic M; Lemery R; Nattel S; Cassidy D
Electrophysiologic evaluation and outcome of patients with syncope of unknown origin.
European heart journal 1991;12(2):139-43.
1990: Nattel S; Wang Z G; Matthews C
Direct electrophysiological actions of pentobarbital at concentrations achieved during general anesthesia.
The American journal of physiology 1990;259(6 Pt 2):H1743-51.
1990: Nattel S; Talajic M; Goldstein R E; McCans J
Determinants and significance of diltiazem plasma concentrations after acute myocardial infarction. The Multicenter Diltiazem Postinfarction Trial Research Group.
The American journal of cardiology 1990;66(20):1422-8.
1990: Nayebpour M; Talajic M; Villemaire C; Nattel S
Vagal modulation of the rate-dependent properties of the atrioventricular node.
Circulation research 1990;67(5):1152-66.
1990: Nattel S; Ranger S; Talajic M; Lemery R; Roy D
Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism.
The American journal of medicine 1990;89(2):235-8.
1990: Nattel S; Waters D
What is an antiarrhythmic drug? From clinical trials to fundamental concepts.
The American journal of cardiology 1990;66(1):96-9.
1990: Wang Z G; Pelletier L C; Talajic M; Nattel S
Effects of flecainide and quinidine on human atrial action potentials. Role of rate-dependence and comparison with guinea pig, rabbit, and dog tissues.
Circulation 1990;82(1):274-83.
1990: Talajic M; Villemaire C; Nattel S
Electrophysiological effects of alpha-adrenergic stimulation.
Pacing and clinical electrophysiology : PACE 1990;13(5):578-82.
1990: Nayebpour M; Talajic M; Jing W; Nattel S
Autonomic modulation of the frequency-dependent actions of diltiazem on the atrioventricular node in anesthetized dogs.
The Journal of pharmacology and experimental therapeutics 1990;253(1):353-61.
1990: Nayebpour M; Nattel S
Pharmacologic response of cesium-induced ventricular tachyarrhythmias in anesthetized dogs.
Journal of cardiovascular pharmacology 1990;15(4):552-61.
1990: Talajic M; Villemaire C; Papadatos D; Lemery R; Roy D; Nattel S
Cycle length alternation during supraventricular tachycardia: occurrence and mechanism in a canine model of AV reentrant tachycardia.
Pacing and clinical electrophysiology : PACE 1990;13(3):314-25.
1990: Talajic M; Papadatos D; Villemaire C; Nayebpour M; Nattel S
Antiarrhythmic actions of diltiazem during experimental atrioventricular reentrant tachycardias. Importance of use-dependent calcium channel-blocking properties.
Circulation 1990;81(1):334-42.
1989: Nattel S; Jing W
Rate-dependent changes in intraventricular conduction produced by procainamide in anesthetized dogs. A quantitative analysis based on the relation between phase 0 inward current and conduction velocity.
Circulation research 1989;65(6):1485-98.
1989: Lemery R; Talajic M; Nattel S; Theroux P; Roy D
Sinus node dysfunction and sudden cardiac death following treatment with encainide.
Pacing and clinical electrophysiology : PACE 1989;12(10):1607-12.
1989: Nayebpour M; Solymoss B C; Nattel S
Cardiovascular and metabolic effects of caesium chloride injection in dogs--limitations as a model for the long QT syndrome.
Cardiovascular research 1989;23(9):756-66.
1989: Talajic M; Nayebpour M; Jing W; Nattel S
Frequency-dependent effects of diltiazem on the atrioventricular node during experimental atrial fibrillation.
Circulation 1989;80(2):380-9.
1989: Ranger S; Talajic M; Lemery R; Roy D; Nattel S
Amplification of flecainide-induced ventricular conduction slowing by exercise. A potentially significant clinical consequence of use-dependent sodium channel blockade.
Circulation 1989;79(5):1000-6.
1989: Nattel S; Feder-Elituv R; Matthews C; Nayebpour M; Talajic M
Concentration dependence of class III and beta-adrenergic blocking effects of sotalol in anesthetized dogs.
Journal of the American College of Cardiology 1989;13(5):1190-4.
1989: Talajic M; Nattel S; Davies M; McCans J
Attenuation of class 3 and sinus node effects of amiodarone by experimental hypothyroidism.
Journal of cardiovascular pharmacology 1989;13(3):447-50.
1988: Nattel S; Quantz M A
Pharmacological response of quinidine induced early afterdepolarisations in canine cardiac Purkinje fibres: insights into underlying ionic mechanisms.
Cardiovascular research 1988;22(11):808-17.
1988: Nattel S; Talajic M
Recent advances in understanding the pharmacology of amiodarone.
Drugs 1988;36(2):121-31.
1988: Nattel S; Davies M; Quantz M
The antiarrhythmic efficacy of amiodarone and desethylamiodarone, alone and in combination, in dogs with acute myocardial infarction.
Circulation 1988;77(1):200-8.
1987: Shrier A; Dubarsky H; Rosengarten M; Guevara M R; Nattel S; Glass L
Prediction of complex atrioventricular conduction rhythms in humans with use of the atrioventricular nodal recovery curve.
Circulation 1987;76(6):1196-205.
1987: Nattel S; Beau S; McCarragher G
Effect of frequent ventricular ectopy on myocardial infarct size in dogs.
Cardiovascular research 1987;21(4):286-92.

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