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Cord Naujokat

Research Profile

Chemicals & Drugs

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Kidney Transplantation

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Publications

TOP 3
Cord Naujokat; Roman Steinhart
Salinomycin as a drug for targeting human cancer stem cells.
Cord Naujokat; Dominik Fuchs; Gerhard Opelz
Salinomycin in cancer: A new mission for an old agent.
Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Jan Schmidt; Arianeb Mehrabi; Martin Zeier; Gerhard Opelz
Decreasing plasma soluble IL-1 receptor antagonist and increasing monocyte activation early post-transplant may be involved in pathogenesis of delayed graft function in renal transplant recipients.

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All Publications

2012: Cord Naujokat; Roman Steinhart
Salinomycin as a drug for targeting human cancer stem cells.
Journal of biomedicine & biotechnology 2012;2012():950658.
2010: Cord Naujokat; Dominik Fuchs; Gerhard Opelz
Salinomycin in cancer: A new mission for an old agent.
Molecular medicine reports 2010;3(4):555-9.
2010: Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Jan Schmidt; Arianeb Mehrabi; Martin Zeier; Gerhard Opelz
Decreasing plasma soluble IL-1 receptor antagonist and increasing monocyte activation early post-transplant may be involved in pathogenesis of delayed graft function in renal transplant recipients.
Clinical transplantation 2010;24(3):415-23.
2010: Dominik Fuchs; Volker Daniel; Mahmoud Sadeghi; Gerhard Opelz; Cord Naujokat
Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells.
Biochemical and biophysical research communications 2010;394(4):1098-104.
2010: Volker Daniel; Cord Naujokat; Mahmoud Sadeghi; Fabrice Christoph Renner; Rolf Weimer; Gerhard Opelz
Association of high IFN-gamma plasma levels with low B-cell counts in renal transplant recipients with stable long-term graft function.
Clinical transplantation 2010;24(2):281-9.
2010: Volker Daniel; Cord Naujokat; Mahmoud Sadeghi; Rainer Zimmermann; Angela Huth-Kühne; Gerhard Opelz
Increased peripheral blood leukocyte subsets with regulatory phenotype in clinically stable long-term HIV-infected hemophilia patients on HAART may be beneficial and contribute to a decrease in autoimmunity.
Viral immunology 2010;23(1):87-97.
2009: Dominik Fuchs; Andreas Heinold; Gerhard Opelz; Volker Daniel; Cord Naujokat
Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells.
Biochemical and biophysical research communications 2009;390(3):743-9.
2009: Mahmoud Sadeghi; Volker Daniel; Paul Schnitzler; Imad Lahdou; Cord Naujokat; Martin Zeier; Gerhard Opelz
Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria.
Transplantation 2009;88(9):1109-16.
2009: Carsten Berges; Heinrich Haberstock; Dominik Fuchs; Mahmoud Sadeghi; Gerhard Opelz; Volker Daniel; Cord Naujokat
Proteasome inhibition activates the mitochondrial pathway of apoptosis in human CD4+ T cells.
Journal of cellular biochemistry 2009;108(4):935-46.
2009: Gerhard Opelz; Volker Daniel; Cord Naujokat; Bernd Döhler
Epidemiology of pretransplant EBV and CMV serostatus in relation to posttransplant non-Hodgkin lymphoma.
Transplantation 2009;88(8):962-7.
2009: Carsten Berges; Dominik Fuchs; Gerhard Opelz; Volker Daniel; Cord Naujokat
Helenalin suppresses essential immune functions of activated CD4+ T cells by multiple mechanisms.
Molecular immunology 2009;46(15):2892-901.
2009: Mahmoud Sadeghi; Volker Daniel; Imad Lahdou; Bernd Döhler; Cord Naujokat; Fabrice C Renner; Rolf Weimer; Hamidreza Fonouni; Arianeb Mehrabi; Jan Schmidt; Martin Schenk; Martin Zeier; Gerhard Opelz
Association of pretransplant soluble glycoprotein 130 (sgp130) plasma levels and posttransplant acute tubular necrosis in renal transplant recipients.
Transplantation 2009;88(2):266-71.
2009: Cord Naujokat
Role of ubiquitin ligases in neural stem and progenitor cells.
Archivum immunologiae et therapiae experimentalis 2009;57(3):177-88.
2008: Dominik Fuchs; Carsten Berges; Gerhard Opelz; Volker Daniel; Cord Naujokat
HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway.
Biochemical and biophysical research communications 2008;374(2):309-14.
2008: Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Paul Schnitzler; Jan Schmidt; Arianeb Mehrabi; Martin Zeier; Gerhard Opelz
Dysregulated cytokine responses during cytomegalovirus infection in renal transplant recipients.
Transplantation 2008;86(2):275-85.
2008: Volker Daniel; Cord Naujokat; Mahmoud Sadeghi; Rolf Weimer; Fabrice Renner; Sevgi Yildiz; Gerhard Opelz
Observational support for an immunoregulatory role of CD3+CD4+CD25+IFN-gamma+ blood lymphocytes in kidney transplant recipients with good long-term graft outcome.
Transplant international : official journal of the European Society for Organ Transplantation 2008;21(7):646-60.
2008: Carsten Berges; Heinrich Haberstock; Dominik Fuchs; Marion Miltz; Mahmoud Sadeghi; Gerhard Opelz; Volker Daniel; Cord Naujokat
Proteasome inhibition suppresses essential immune functions of human CD4+ T cells.
Immunology 2008;124(2):234-46.
2008: Volker Daniel; Cord Naujokat; Mahmoud Sadeghi; Rainer Zimmermann; Angela Huth-Kühne; Gerhard Opelz
Normal or even increased dendritic cell and peripheral blood lymphocyte subsets with regulatory phenotype in clinically stable long-term HIV-infected patients with hemophilia on highly active antiretroviral therapy.
Journal of acquired immune deficiency syndromes (1999) 2008;47(1):1-15.
2008: Volker Daniel; Cord Naujokat; Mahmoud Sadeghi; Rainer Zimmermann; Angela Huth-Kühne; Gerhard Opelz
Association of IL-12+ DC with High CD3+CD4-DR+ lymphocyte counts in long-term HIV-infected hemophilia patients with clinically stable disease.
Journal of clinical immunology 2008;28(1):58-72.
2008: Dominik Fuchs; Carsten Berges; Gerhard Opelz; Volker Daniel; Cord Naujokat
Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells.
Journal of cellular biochemistry 2008;103(1):270-83.
2007: Cord Naujokat; Tomo Sarić
Concise review: role and function of the ubiquitin-proteasome system in mammalian stem and progenitor cells.
Stem cells (Dayton, Ohio) 2007;25(10):2408-18.
2007: Cord Naujokat; Dominik Fuchs; Carsten Berges
Adaptive modification and flexibility of the proteasome system in response to proteasome inhibition.
Biochimica et biophysica acta 2007;1773(9):1389-97.
2007: Mahmoud Sadeghi; Caner Süsal; Volker Daniel; Cord Naujokat; Rainer Zimmermann; Angela Huth-Kühne; Gerhard Opelz
Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy.
AIDS research and human retroviruses 2007;23(7):886-90.
2007: Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Jan Schmidt; Arianeb Mehrabi; Martin Zeier; Gerhard Opelz
Evidence for IFN-gamma up- and IL-4 downregulation late post-transplant in patients with good kidney graft outcome.
Clinical transplantation 2007;21(4):449-59.
2007: Gerhard Opelz; Volker Daniel; Cord Naujokat; Helmut Fickenscher; Bernd Döhler
Effect of cytomegalovirus prophylaxis with immunoglobulin or with antiviral drugs on post-transplant non-Hodgkin lymphoma: a multicentre retrospective analysis.
The lancet oncology 2007;8(3):212-8.
2007: Cord Naujokat; Carsten Berges; Dominik Fuchs; Mahmoud Sadeghi; Gerhard Opelz; Volker Daniel
Antithymocyte globulins suppress dendritic cell function by multiple mechanisms.
Transplantation 2007;83(4):485-97.
2007: Cord Naujokat; Carsten Berges; Alexandra Höh; Hubert Wieczorek; Dominik Fuchs; Jörg Ovens; Marion Miltz; Mahmoud Sadeghi; Gerhard Opelz; Volker Daniel
Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells.
Immunology 2007;120(1):120-32.
2006: Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Arianeb Mehrabi; Gerhard Opelz
Association of high pretransplant sIL-6R plasma levels with acute tubular necrosis in kidney graft recipients.
Transplantation 2006;81(12):1716-24.
2006: Gerhard Opelz; Cord Naujokat; Volker Daniel; Peter Terness; Bernd Döhler
Disassociation between risk of graft loss and risk of non-Hodgkin lymphoma with induction agents in renal transplant recipients.
Transplantation 2006;81(9):1227-33.
2005: Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Rolf Weimer; Gerhard Opelz
Strikingly higher interleukin (IL)-1alpha, IL-1beta and soluble interleukin-1 receptor antagonist (sIL-1RA) but similar IL-2, sIL-2R, IL-3, IL-4, IL-6, sIL-6R, IL-10, tumour necrosis factor (TNF)-alpha, transforming growth factor (TGF)-beta and interferon IFN-gamma urine levels in healthy females compared to healthy males: protection against urinary tract injury?
Clinical and experimental immunology 2005;142(2):312-7.
2005: Carsten Berges; Cord Naujokat; Sarah Tinapp; Hubert Wieczorek; Alexandra Höh; Mahmoud Sadeghi; Gerhard Opelz; Volker Daniel
A cell line model for the differentiation of human dendritic cells.
Biochemical and biophysical research communications 2005;333(3):896-907.
2005: Volker Daniel; Cord Naujokat; Mahmoud Sadeghi; Manfred Wiesel; Olaf Hergesell; Gerhard Opelz
Association of circulating interleukin (IL)-12- and IL-10-producing dendritic cells with time posttransplant, dose of immunosuppression, and plasma cytokines in renal-transplant recipients.
Transplantation 2005;79(11):1498-506.
2005: Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Manfred Wiesel; Olaf Hergesell; Gerhard Opelz
Strong inflammatory cytokine response in male and strong anti-inflammatory response in female kidney transplant recipients with urinary tract infection.
Transplant international : official journal of the European Society for Organ Transplantation 2005;18(2):177-85.
2004: Jakub Golab; Thomas M Bauer; Volker Daniel; Cord Naujokat
Role of the ubiquitin-proteasome pathway in the diagnosis of human diseases.
Clinica chimica acta; international journal of clinical chemistry 2004;340(1-2):27-40.
2004: Mahmoud Sadeghi; Volker Daniel; Cord Naujokat; Caner Süsal; Rolf Weimer; Angela Huth-Kühne; Rainer Zimmermann; Gerhard Opelz
Dissociation of CD4(+) cell counts from viral load and association with immune complexes in HIV(+) hemophilia patients.
Immunology letters 2004;91(1):23-32.
2004: Volker Daniel; Mahmoud Sadeghi; Cord Naujokat; Rolf Weimer; Angela Huth-Kühne; Rainer Zimmermann; Gerhard Opelz
Evidence for autoantibody-induced CD4 depletion mediated by apoptotic and non-apoptotic mechanisms in HIV-positive long-term surviving haemophilia patients.
Clinical and experimental immunology 2004;135(1):94-104.
2003: Cord Naujokat; Volker Daniel; Thomas M Bauer; Mahmoud Sadeghi; Gerhard Opelz
Cell cycle- and activation-dependent regulation of cyclosporin A-induced T cell apoptosis.
Biochemical and biophysical research communications 2003;310(2):347-54.
2003: Ivana Zavrski; Cord Naujokat; Kathrin Niemöller; Christian Jakob; Ulrike Heider; Corinna Langelotz; Claudia Fleissner; Jan Eucker; Kurt Possinger; Orhan Sezer
Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion.
Journal of cancer research and clinical oncology 2003;129(7):383-91.
2002: Cord Naujokat; Stephan Hoffmann
Role and function of the 26S proteasome in proliferation and apoptosis.
Laboratory investigation; a journal of technical methods and pathology 2002;82(8):965-80.
2000: Cord Naujokat; Orhan Sezer; H Zinke; Anja Leclere; Steffen Hauptmann; Kurt Possinger
Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.
European journal of haematology 2000;65(4):221-36.
1999: Cord Naujokat; Orhan Sezer; Kurt Possinger
Tumor necrosis factor-alpha and interferon-gamma induce expression of functional Fas ligand on HT29 and MCF7 adenocarcinoma cells.
Biochemical and biophysical research communications 1999;264(3):813-9.