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Nora Navone

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Maria Karlou; Christopher J Logothetis; Jing-Fang Lu; Sankar Maity; Nora M Navone; Vassiliki Tzelepi; Guanglin Wu; Anh Hoang; Eleni Efstathiou
Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b.
J Yang; Y Zheng; Y Cao; J He; S Hong; L W Kwak; Y Lan; H Li; Pei Lin; J Ling; Y Lu; J Matthews; Nora M Navone; Robert Z Orlowski; Jianfei Qian; M W Starbuck; J Wang; Qing Yi
Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma.
Kanishka Sircar; Patricia Troncoso; Vassiliki Tzelepi; Ana Aparicio; Tarek A Bismar; David Cogdell; Jasreman Dhillon; Eleni Efstathiou; Limei Hu; Heng Huang; Ismaël H Koumakpayi; Dijun Luo; Nora M Navone; Fred Saad; Wei Zhang
Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.

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2012: Maria Karlou; Christopher J Logothetis; Jing-Fang Lu; Sankar Maity; Nora M Navone; Vassiliki Tzelepi; Guanglin Wu; Anh Hoang; Eleni Efstathiou
Hedgehog signaling inhibition by the small molecule smoothened inhibitor GDC-0449 in the bone forming prostate cancer xenograft MDA PCa 118b.
The Prostate 2012;72(15):1638-47.
2012: J Yang; Y Zheng; Y Cao; J He; S Hong; L W Kwak; Y Lan; H Li; Pei Lin; J Ling; Y Lu; J Matthews; Nora M Navone; Robert Z Orlowski; Jianfei Qian; M W Starbuck; J Wang; Qing Yi
Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma.
Leukemia 2012;26(9):2114-23.
2012: Kanishka Sircar; Patricia Troncoso; Vassiliki Tzelepi; Ana Aparicio; Tarek A Bismar; David Cogdell; Jasreman Dhillon; Eleni Efstathiou; Limei Hu; Heng Huang; Ismaël H Koumakpayi; Dijun Luo; Nora M Navone; Fred Saad; Wei Zhang
Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.
The American journal of pathology 2012;180(3):895-903.
2012: Xinhai Wan; Jun Yang; Jonathan M Yingling; Vikas Kundra; Zhi-Gang Li; Murali K Ravoori; Michael W Starbuck; Elba Vazquez; Nora M Navone
Effect of transforming growth factor beta (TGF-β) receptor I kinase inhibitor on prostate cancer bone growth.
Bone 2012;50(3):695-703.
2012: Xinhai Wan; Jing Wang; Jun Yang; Lixia Diao; Eleni Efstathiou; Jie Liu; Jing-Fang Lu; Sankar N Maity; Michael W Starbuck; Patricia Troncoso; Vassiliki Tzelepi; Elba S Vazquez; Nora M Navone
Activation of β-catenin signaling in androgen receptor-negative prostate cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(3):726-36.
2012: Vassiliki Tzelepi; Xinhai Wan; Guanglin Wu; Jiexin Zhang; Eleni Efstathiou; Anh Hoang; Brittany Kleb; Shoudan Liang; Christopher J Logothetis; Jing-Fang Lu; Sankar N Maity; Nora M Navone; Kanishka Sircar; Patricia Troncoso; Ana M Aparicio
Modeling a lethal prostate cancer variant with small-cell carcinoma features.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(3):666-77.
2012: Kanishka Sircar; Patricia Troncoso; Armen G Aprikian; David Cogdell; Jasreman Dhillon; Eleni Efstathiou; Limei Hu; Heng Huang; Yuexin Liu; Nora M Navone; Wei Zhang
Mitosis phase enrichment with identification of mitotic centromere-associated kinesin as a therapeutic target in castration-resistant prostate cancer.
PloS one 2012;7(2):e31259.
2011: Ana Aparicio; Vasiliki Tzelepi; John C Araujo; Charles C Guo; Shoudan Liang; Patricia Troncoso; Christopher J Logothetis; Nora M Navone; Sankar N Maity
Neuroendocrine prostate cancer xenografts with large-cell and small-cell features derived from a single patient's tumor: morphological, immunohistochemical, and gene expression profiles.
The Prostate 2011;71(8):846-56.
2011: Khalid A Mohamedali; Zhi Gang Li; Michael W Starbuck; Xinhai Wan; Jun Yang; Sehoon Kim; Wendy Zhang; Michael G Rosenblum; Nora M Navone
Inhibition of prostate cancer osteoblastic progression with VEGF121/rGel, a single agent targeting osteoblasts, osteoclasts, and tumor neovasculature.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(8):2328-38.
2011: Charles C Guo; Jane Y Dancer; Yan Wang; Ana Aparicio; Nora M Navone; Patricia Troncoso; Bogdan A Czerniak
TMPRSS2-ERG gene fusion in small cell carcinoma of the prostate.
Human pathology 2011;42(1):11-7.
2010: Lukas Prantl; Fabian Muehlberg; Nora M Navone; Yao-Hua Song; Jody Vykoukal; Christopher J Logothetis; Eckhard U Alt
Adipose tissue-derived stem cells promote prostate tumor growth.
The Prostate 2010;70(15):1709-15.
2010: Nora M Navone
P-TEFb joins the family of cdks in oncology, promotes cell growth of cancer cells.
Cell cycle (Georgetown, Tex.) 2010;9(15):2935.
2010: Yu-Chen Lee; Chien-Jui Cheng; Miao Huang; Mehmet A Bilen; Xiangcang Ye; Nora M Navone; Khoi Chu; Hsin-Hsin Kao; Li-Yuan Yu-Lee; Zhengxin Wang; Sue-Hwa Lin
Androgen depletion up-regulates cadherin-11 expression in prostate cancer.
The Journal of pathology 2010;221(1):68-76.
2010: Ivan P Gorlov; Kanishka Sircar; Hongya Zhao; Sankar N Maity; Nora M Navone; Olga Y Gorlova; Patricia Troncoso; Curtis A Pettaway; Jin Young Byun; Christopher J Logothetis
Prioritizing genes associated with prostate cancer development.
BMC cancer 2010;10():599.
2010: Murali Ravoori; Aneta J Czaplinska; Charles Sikes; Lin Han; Evan M Johnson; Wei Qiao; Chaan Ng; Dianna D Cody; William A Murphy; Kim-Anh Do; Nora M Navone; Vikas Kundra
Quantification of mineralized bone response to prostate cancer by noninvasive in vivo microCT and non-destructive ex vivo microCT and DXA in a mouse model.
PloS one 2010;5(3):e9854.
2008: Sue-Hwa Lin; C-J Cheng; Yung-Chie Lee; Xiangcang Ye; W-W Tsai; Jeri Kim; Renata Pasqualini; Wadih Arap; Nora M Navone; Shi-Ming Tu; M Hu; Li-Yuan Yu-Lee; Christopher J Logothetis
A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation.
Oncogene 2008;27(39):5195-203.
2008: Zhi Gang Li; Paul Mathew; Jun Yang; Michael W Starbuck; Amado J Zurita; Jie Liu; Charles R Sikes; Asha S Multani; Eleni Efstathiou; Adriana Lopez; Jing Wang; Tina V Fanning; Victor G Prieto; Vikas Kundra; Elba S Vazquez; Patricia Troncoso; Austin K Raymond; Christopher J Logothetis; Sue-Hwa Lin; Sankar Maity; Nora M Navone
Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms.
The Journal of clinical investigation 2008;118(8):2697-710.
2008: Christopher J Logothetis; Nora M Navone; Sue-Hwa Lin
Understanding the biology of bone metastases: key to the effective treatment of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(6):1599-602.
2008: Z G Li; J Yang; E S Vazquez; D Rose; Funda Vakar-Lopez; P Mathew; A Lopez; Christopher J Logothetis; Sue-Hwa Lin; Nora M Navone
Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone.
Oncogene 2008;27(5):596-603.
2007: Nanyue Chen; Xiang-cang Ye; Khoi Chu; Nora M Navone; E Helene Sage; Li-Yuan Yu-Lee; Christopher J Logothetis; Sue-Hwa Lin
A secreted isoform of ErbB3 promotes osteonectin expression in bone and enhances the invasiveness of prostate cancer cells.
Cancer research 2007;67(14):6544-8.
2007: Chien-Jui Cheng; Xiang-cang Ye; Funda Vakar-Lopez; Jeri Kim; Shi-Ming Tu; Dung-Tsa Chen; Nora M Navone; Li-Yuan Yu-Lee; Sue-Hwa Lin; Mickey C-T Hu
Bone microenvironment and androgen status modulate subcellular localization of ErbB3 in prostate cancer cells.
Molecular cancer research : MCR 2007;5(7):675-84.
2007: Vikas Kundra; Chaan S Ng; Jingfei Ma; James Bankson; Roger E Price; Dianna D Cody; Kim-Anh Do; Lin Han; Nora M Navone
In vivo imaging of prostate cancer involving bone in a mouse model.
The Prostate 2007;67(1):50-60.
2006: Khalid A Mohamedali; Ann T Poblenz; Charles R Sikes; Nora M Navone; Philip E Thorpe; Bryant G Darnay; Michael G Rosenblum
Inhibition of prostate tumor growth and bone remodeling by the vascular targeting agent VEGF121/rGel.
Cancer research 2006;66(22):10919-28.
2005: Sara Peleg; Farhana Khan; Nora M Navone; Dianna D Cody; Evan M Johnson; Carolyn S Van Pelt; Gary H Posner
Inhibition of prostate cancer-meditated osteoblastic bone lesions by the low-calcemic analog 1alpha-hydroxymethyl-16-ene-26,27-bishomo-25-hydroxy vitamin D3.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):203-11.
2005: Karim Fizazi; Nora M Navone
[Preclinical models of prostate cancer].
Bulletin du cancer 2005;92(2):129-41.
2004: Karim Fizazi; Charles R Sikes; Jeri Kim; Jun Yang; Luis A. Martinez; Matilde C Olive; Christopher J Logothetis; Nora M Navone
High efficacy of docetaxel with and without androgen deprivation and estramustine in preclinical models of advanced prostate cancer.
Anticancer research 2004;24(5A):2897-903.
2004: Nora M Navone; Matilde Olive; Patricia Troncoso
Isolation and culture of prostate cancer cell lines.
Methods in molecular medicine 2004;88():121-32.
2003: Karim Fizazi; Jun Yang; Sara Peleg; Charles R Sikes; Erica L Kreimann; Danai D Daliani; Matilde Olive; Kevin A Raymond; Todd J Janus; Christopher J Logothetis; Gerard Karsenty; Nora M Navone
Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2587-97.
2003: Christopher Logothetis; Shi-Ming Tu; Nora M Navone
Targeting prostate cancer bone metastases.
Cancer 2003;97(3 Suppl):785-8.
2002: Luis A. Martinez; Jun Yang; Elba S Vazquez; María del Carmen Rodriguez-Vargas; Matilde Olive; Jer-Tsong Hsieh; Christopher J Logothetis; Nora M Navone
p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells.
Carcinogenesis 2002;23(8):1289-96.
2002: Liesbeth M Veenendaal; Hangqing Jin; Sophia Ran; Lawrence Cheung; Nora M Navone; John W Marks; Johannes Waltenberger; Philip E Thorpe; Michael G Rosenblum
In vitro and in vivo studies of a VEGF121/rGelonin chimeric fusion toxin targeting the neovasculature of solid tumors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):7866-71.
2002: Karim Fizazi; Luis A. Martinez; Charles R Sikes; Dennis A Johnston; L Clifton Stephens; Timothy J McDonnell; Christopher J Logothetis; Jon Trapman; Louis L Pisters; Nelson G Ordoñez; Patricia Troncoso; Nora M Navone
The association of p21((WAF-1/CIP1)) with progression to androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):775-81.
2002: Artur Plonowski; Andrew V Schally; Attila Nagy; Kate Groot; Magdalena Krupa; Nora M Navone; Christopher Logothetis
Inhibition of in vivo proliferation of MDA-PCa-2b human prostate cancer by a targeted cytotoxic analog of luteinizing hormone-releasing hormone AN-207.
Cancer letters 2002;176(1):57-63.
2001: Robert A Newman; J Yang; M Raymond; V Finlay; F Cabral; D Vourloumis; L Clifton Stephens; Patricia Troncoso; X Wu; Christopher J Logothetis; K C Nicolaou; Nora M Navone
Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts.
Cancer chemotherapy and pharmacology 2001;48(4):319-26.
2001: Jun Yang; Karim Fizazi; Sara Peleg; Charles R Sikes; A Kevin Raymond; N Jamal; Min Hu; Matilde Olive; Luis A. Martinez; Christopher G Wood; Christopher J Logothetis; Gerard Karsenty; Nora M Navone
Prostate cancer cells induce osteoblast differentiation through a Cbfa1-dependent pathway.
Cancer research 2001;61(14):5652-9.
2000: Nora M Navone; M C Rodriquez-Vargas; William F Benedict; Patricia Troncoso; Timothy J McDonnell; J H Zhou; Rajyalakshmi Luthra; Christopher J Logothetis
TabBO: a model reflecting common molecular features of androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):1190-7.
1999: Nora M Navone; Michael LaBate; Patricia Troncoso; Louis L Pisters; C J Conti; Andrew C von Eschenbach; Christopher J Logothetis
p53 mutations in prostate cancer bone metastases suggest that selected p53 mutants in the primary site define foci with metastatic potential.
The Journal of urology 1999;161(1):304-8.
1998: M Ozen; Nora M Navone; Asha S Multani; P Troncoso; Christopher J Logothetis; Leland W K Chung; Andrew C von Eschenbach; Sen Pathak
Structural alterations of chromosome 5 in twelve human prostate cancer cell lines.
Cancer genetics and cytogenetics 1998;106(2):105-9.
1998: Louis L Pisters; Patricia Troncoso; Nora M Navone
Prolonged survival with metastatic prostate cancer to bone.
The Journal of urology 1998;159(6):2100.
1998: S Rajagopal; Nora M Navone; Patricia Troncoso; H A Fritsche; S Chakrabarty
Modulation of cellular proliferation and production of prostate-specific antigen and matrix adhesion molecules in human prostate carcinoma cells by polypeptide growth factors: comparative analyses of MDA PCa2a with established cell lines.
International journal of oncology 1998;12(3):589-95.
1998: Nora M Navone; Christopher J Logothetis; Andrew C von Eschenbach; Patricia Troncoso
Model systems of prostate cancer: uses and limitations.
Cancer metastasis reviews 1998;17(4):361-71.
1997: Nora M Navone; Matilde Olive; M Ozen; R Davis; Patricia Troncoso; Shi-Ming Tu; D Johnston; Alan Pollack; Sen Pathak; Andrew C von Eschenbach; Christopher J Logothetis
Establishment of two human prostate cancer cell lines derived from a single bone metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 1):2493-500.
1997: CF Polo; Ana María Buzaleh; Elba S Vazquez; SG Afonso; Nora M Navone; Alcira Batlle
Griseofulvin-induced hepatopathy due to abnormalities in heme pathway.
General pharmacology 1997;29(2):207-10.
1997: Timothy J McDonnell; Nora M Navone; Patricia Troncoso; Louis L Pisters; C Conti; Andrew C von Eschenbach; Shawn Brisbay; Christopher J Logothetis
Expression of bcl-2 oncoprotein and p53 protein accumulation in bone marrow metastases of androgen independent prostate cancer.
The Journal of urology 1997;157(2):569-74.
1995: M C Hall; Nora M Navone; Patricia Troncoso; Alan Pollack; Gunar K Zagars; Andrew C von Eschenbach; C J Conti; Leland W K Chung
Frequency and characterization of p53 mutations in clinically localized prostate cancer.
Urology 1995;45(3):470-5.
1993: Nora M Navone; Patricia Troncoso; Louis L Pisters; Tamra Goodrow; J L Palmer; W W Nichols; Andrew C von Eschenbach; Claudio J Conti
p53 protein accumulation and gene mutation in the progression of human prostate carcinoma.
Journal of the National Cancer Institute 1993;85(20):1657-69.