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Kanyile Ncokazi

Research Profile

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Publications

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Jill M Combrinck; Melvin A Ambele; Heinrich C Hoppe; Tebogo E Mabotha; Kanyile K Ncokazi; Peter J Smith; Dale Taylor; Timothy J Egan
Insights into the role of heme in the mechanism of action of antimalarials.
Faustine Dubar; Timothy J Egan; Bruno Pradines; David Kuter; Kanyile K Ncokazi; Delphine Forge; Jean-François Paul; Christine Pierrot; Hadidjatou Kalamou; Jamal Khalife; Eric Buisine; Christophe Rogier; Hervé Vezin; Isabelle Forfar; Christian Slomianny; Xavier Trivelli; Sergey Kapishnikov; Leslie Leiserowitz; Daniel Dive; christophe biot
The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance.
Anh N Hoang; Kanyile K Ncokazi; Katherine A de Villiers; David W Wright; Timothy J Egan
Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles.

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All Publications

2013: Jill M Combrinck; Melvin A Ambele; Heinrich C Hoppe; Tebogo E Mabotha; Kanyile K Ncokazi; Peter J Smith; Dale Taylor; Timothy J Egan
Insights into the role of heme in the mechanism of action of antimalarials.
ACS chemical biology 2013;8(1):133-7.
2011: Faustine Dubar; Timothy J Egan; Bruno Pradines; David Kuter; Kanyile K Ncokazi; Delphine Forge; Jean-François Paul; Christine Pierrot; Hadidjatou Kalamou; Jamal Khalife; Eric Buisine; Christophe Rogier; Hervé Vezin; Isabelle Forfar; Christian Slomianny; Xavier Trivelli; Sergey Kapishnikov; Leslie Leiserowitz; Daniel Dive; christophe biot
The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance.
ACS chemical biology 2011;6(3):275-87.
2010: Anh N Hoang; Kanyile K Ncokazi; Katherine A de Villiers; David W Wright; Timothy J Egan
Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles.
Dalton transactions (Cambridge, England : 2003) 2010;39(5):1235-44.
2006: Timothy J Egan; Jeff Y-J Chen; Katherine A De Villiers; Tebogo E Mabotha; Kevin J Naidoo; Kanyile K Ncokazi; Steven J Langford; Don McNaughton; Shveta Pandiancherri; Bayden Wood
Haemozoin (beta-haematin) biomineralization occurs by self-assembly near the lipid/water interface.
FEBS letters 2006;580(21):5105-10.
2005: Timothy J Egan; Kanyile K Ncokazi
Quinoline antimalarials decrease the rate of beta-hematin formation.
Journal of inorganic biochemistry 2005;99(7):1532-9.
2005: Kanyile K Ncokazi; Timothy J Egan
A colorimetric high-throughput beta-hematin inhibition screening assay for use in the search for antimalarial compounds.
Analytical biochemistry 2005;338(2):306-19.
2004: Timothy J Egan; Kanyile K Ncokazi
Effects of solvent composition and ionic strength on the interaction of quinoline antimalarials with ferriprotoporphyrin IX.
Journal of inorganic biochemistry 2004;98(1):144-52.
2001: Timothy J Egan; WW Mavuso; Kanyile K Ncokazi
The mechanism of beta-hematin formation in acetate solution. Parallels between hemozoin formation and biomineralization processes.
Biochemistry 2001;40(1):204-13.