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Kai Neben

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Niels Weinhold; Mathias Witzens-Harig; Peter Broderick; Bowang Chen; Daniel Chubb; Faith E Davies; Sara E Dobbins; Lewin Eisele; Asta Försti; Hartmut Goldschmidt; Walter A Gregory; Per Hoffmann; Dirk Hose; Fay J Hosking; Richard S Houlston; Graham H Jackson; Anna Jauch; David C Johnson; Martin F Kaiser; Ni L Li; Yussanne P Ma; Gareth J Morgan; Thomas W Mühleisen; Kai Neben; Markus M Nöthen; Fiona M Ross; Brian A Walker; Kari Hemminki
The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Nikolaus Becker; Anne Byl; Gerlinde Egerer; Susanne Friedrich; Hartmut Goldschmidt; Anthony D Ho; Anna Jauch; Paul Schnitzler; Kai Neben
Hepatitis B virus infection is associated with deletion of chromosome 8p in multiple myeloma.
Isabelle Herth; Anthony D Ho; Dirk Hose; Philipp Beckhove; Melanie Engelhardt; Hartmut Goldschmidt; Jürgen Haas; Bernard Klein; Tobias Meissner; Kai Neben; Brigitte Neuber; Mathias Witzens-Harig; Michael Hundemer
Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma.

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All Publications

2013: Niels Weinhold; Mathias Witzens-Harig; Peter Broderick; Bowang Chen; Daniel Chubb; Faith E Davies; Sara E Dobbins; Lewin Eisele; Asta Försti; Hartmut Goldschmidt; Walter A Gregory; Per Hoffmann; Dirk Hose; Fay J Hosking; Richard S Houlston; Graham H Jackson; Anna Jauch; David C Johnson; Martin F Kaiser; Ni L Li; Yussanne P Ma; Gareth J Morgan; Thomas W Mühleisen; Kai Neben; Markus M Nöthen; Fiona M Ross; Brian A Walker; Kari Hemminki
The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Nature genetics 2013;45(5):522-5.
2013: Nikolaus Becker; Anne Byl; Gerlinde Egerer; Susanne Friedrich; Hartmut Goldschmidt; Anthony D Ho; Anna Jauch; Paul Schnitzler; Kai Neben
Hepatitis B virus infection is associated with deletion of chromosome 8p in multiple myeloma.
European journal of haematology 2013;90(4):279-85.
2013: Isabelle Herth; Anthony D Ho; Dirk Hose; Philipp Beckhove; Melanie Engelhardt; Hartmut Goldschmidt; Jürgen Haas; Bernard Klein; Tobias Meissner; Kai Neben; Brigitte Neuber; Mathias Witzens-Harig; Michael Hundemer
Thalidomide maintenance therapy maturates the T cell compartment and compromises antigen-specific antitumor immunity in patients with multiple myeloma.
Experimental hematology 2013;41(3):231-40.
2013: Steffen Geis; Klaus Heeg; Anthony D Ho; Hans-Georg Kräusslich; Nicola Lehners; Kai Neben; Christiane Prifert; Elisabeth Aichinger; Udo Buchholz; Ulrich Burkhardt; Peter Dreger; Gerlinde Egerer; Christoph Eisenbach; Benedikt Weissbrich; Paul Schnitzler
Molecular characterization of a respiratory syncytial virus outbreak in a hematology unit in Heidelberg, Germany.
Journal of clinical microbiology 2013;51(1):155-62.
2012: Jens Hillengass; Dirk Hose; Kerstin Kilk; Sofia Ayyaz; Stefan Delorme; Hartmut Goldschmidt; Thomas Hielscher; Rajiv Shah; Marc-André Weber; Kai Neben
Changes in magnetic resonance imaging before and after autologous stem cell transplantation correlate with response and survival in multiple myeloma.
Haematologica 2012;97(11):1757-60.
2012: Christian Kasperk; Peter-Jürgen Meeder; Peter Nawroth; Kai Neben; Dirk Neuhof; Gerd Nöldge; Gerhard Schmidmaier; Ulrike Sommer; Michael Tanner; Christel Weiss; Bernd Wiedenhöfer; Hartmut Goldschmidt; Andreas Haas; Jens Hillengass; Ingo A Grafe
Kyphoplasty in patients with multiple myeloma a retrospective comparative pilot study.
Journal of surgical oncology 2012;105(7):679-86.
2012: Kai Neben; Norma Peter; Michael Pfreundschuh; Marc S Raab; Hans Salwender; Christof Scheid; Ingo G H Schmidt-Wolf; Pieter Sonneveld; Christian Teschendorf; Helgi van de Velde; Bronno van der Holt; Katja Weisel; Mathias Haenel; Thomas Hielscher; Anthony D Ho; Dirk Hose; Anna Jauch; Walter Lindemann; Henk M Lokhorst; Hans Martin; Uta Bertsch; Igor W Blau; Hans G Derigs; Ulrich Dührsen; Hartmut Goldschmidt
Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p.
Blood 2012;119(4):940-8.
2012: Jens Hillengass; Kai Neben; Hartmut Goldschmidt
Meeting report of the third Heidelberg myeloma workshop: current status and developments in diagnosis and therapy of multiple myeloma.
Journal of cancer research and clinical oncology 2012;138(1):173-8.
2011: Dirk Hose; Anna Jauch; Bernard Klein; Jérôme Moreaux; Kai Neben; Thierry Rème; Anja Seckinger; Uta Bertsch; Hartmut Goldschmidt
The role of fluorescence in situ hybridization and gene expression profiling in myeloma risk stratification.
Srpski arhiv za celokupno lekarstvo 2011;139 Suppl 2():84-9.
2011: Stefan Schmitt; Brigitte Storch-Hagenlocher; M Pham; G Fingerle-Rowson; Hartmut Goldschmidt; Anthony Ho; Kai Neben
Inflammatory autoimmune neuropathy, presumably induced by bortezomib, in a patient suffering from multiple myeloma.
International journal of hematology 2011;93(6):791-4.
2011: Ulrike Klein; Anna Jauch; Thomas Hielscher; Jens Hillengass; Marc S Raab; Anja Seckinger; Dirk Hose; Anthony D Ho; Hartmut Goldschmidt; Kai Neben
Chromosomal aberrations +1q21 and del(17p13) predict survival in patients with recurrent multiple myeloma treated with lenalidomide and dexamethasone.
Cancer 2011;117(10):2136-44.
2011: Tilmann Bochtler; Ute Hegenbart; Christiane Heiss; Axel Benner; Marion Moos; Anja Seckinger; Stephanie Pschowski-Zuck; Désirée Kirn; Kai Neben; Claus R Bartram; Anthony D Ho; Hartmut Goldschmidt; Dirk Hose; Anna Jauch; Stefan O Schonland
Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14).
Blood 2011;117(14):3809-15.
2011: Ulrike Klein; Kai Neben; Thomas Hielscher; Christiane Heiss; Anthony D Ho; Hartmut Goldschmidt
Lenalidomide in combination with dexamethasone: effective regimen in patients with relapsed or refractory multiple myeloma complicated by renal impairment.
Annals of hematology 2011;90(4):429-39.
2011: Dirk Hose; Thierry Rème; Thomas Hielscher; Jérôme Moreaux; Tobias Messner; Anja Seckinger; Axel Benner; John D Shaughnessy; Bart Barlogie; Yiming Zhou; Jens Hillengass; Uta Bertsch; Kai Neben; Thomas Möhler; Jean-François Rossi; Anna Jauch; Bernard Klein; Hartmut Goldschmidt
Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma.
Haematologica 2011;96(1):87-95.
2010: Juliane Brandt; Sascha Dietrich; Julia Meissner; Kai Neben; Anthony D Ho; Mathias Witzens-Harig
Quality of life of long-term survivors with Hodgkin lymphoma after high-dose chemotherapy, autologous stem cell transplantation, and conventional chemotherapy.
Leukemia & lymphoma 2010;51(11):2012-20.
2010: Fabienne McClanahan; Thomas Hielscher; Michael Rieger; Manfred Hensel; Kai Neben; Jens Hillengass; Klaus K Herfarth; Anthony D Ho; Mathias Witzens-Harig
Clinical outcome of patients with follicular lymphoma and bulky disease after rituximab-CHOP immunochemotherapy with and without consolidating radiotherapy.
European journal of haematology 2010;85(1):11-9.
2010: Kai Neben; Anna Jauch; Uta Bertsch; Christiane Heiss; Thomas Hielscher; Anja Seckinger; Tina Mors; Nadine Zoe Müller; Jens Hillengass; Marc S Raab; Anthony D Ho; Dirk Hose; Hartmut Goldschmidt
Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation.
Haematologica 2010;95(7):1150-7.
2010: Patrick Wuchter; Dan Ran; Thomas Bruckner; Thomas Schmitt; Mathias Witzens-Harig; Kai Neben; Hartmut Goldschmidt; Anthony D Ho
Poor mobilization of hematopoietic stem cells-definitions, incidence, risk factors, and impact on outcome of autologous transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(4):490-9.
2010: Jens Hillengass; Kerstin Fechtner; Marc-André Weber; Tobias Bäuerle; Sofia Ayyaz; Christiane Heiss; Thomas Hielscher; Thomas M Moehler; Gerlinde Egerer; Kai Neben; Anthony D Ho; Hans-Ulrich Kauczor; Stefan Delorme; Hartmut Goldschmidt
Prognostic significance of focal lesions in whole-body magnetic resonance imaging in patients with asymptomatic multiple myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(9):1606-10.
2010: Jens Hillengass; Kai Neben; Hartmut Goldschmidt
Current status and developments in diagnosis and therapy of multiple myeloma.
Journal of cancer research and clinical oncology 2010;136(1):151-5.
2009: Tobias Bäuerle; Jens Hillengass; Kerstin Fechtner; Christian M Zechmann; Lars Grenacher; Thomas Moehler; Heiss Christiane; Barbara Wagner-Gund; Kai Neben; Hans-Ulrich Kauczor; Hartmut Goldschmidt; Stefan Delorme
Multiple myeloma and monoclonal gammopathy of undetermined significance: importance of whole-body versus spinal MR imaging.
Radiology 2009;252(2):477-85.
2009: Jens Hillengass; Christian M Zechmann; Tobias Bäuerle; Barbara Wagner-Gund; Christiane Heiss; Axel Benner; Anthony Ho; Kai Neben; Dirk Hose; Hans-Ulrich Kauczor; Hartmut Goldschmidt; Stefan Delorme; Thomas Moehler
Dynamic contrast-enhanced magnetic resonance imaging identifies a subgroup of patients with asymptomatic monoclonal plasma cell disease and pathologic microcirculation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(9):3118-25.
2009: Dirk Hose; Thierry Rème; Tobias Meissner; Jérôme Moreaux; Anja Seckinger; Joe Lewis; Vladimir Benes; Axel Benner; Michael Hundemer; Thomas Hielscher; John D Shaughnessy; Bart Barlogie; Kai Neben; Alwin Krämer; Jens Hillengass; Uta Bertsch; Anna Jauch; John De Vos; Jean-François Rossi; Thomas Möhler; Jonathon Blake; Jürgen Zimmermann; Bernard Klein; Hartmut Goldschmidt
Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma.
Blood 2009;113(18):4331-40.
2009: A Krämer; S Gattenlöhner; Kai Neben
[CUP syndrome: molecular pathogenesis and biology].
Der Pathologe 2009;30(2):117-24.
2009: Ulrike Klein; Florentina Kosely; Jens Hillengass; Michael Hundemer; Stefan Schmitt; Kai Neben; Thomas Moehler; Ute Hegenbart; Anthony D Ho; Hartmut Goldschmidt
Effective prophylaxis of thromboembolic complications with low molecular weight heparin in relapsed multiple myeloma patients treated with lenalidomide and dexamethasone.
Annals of hematology 2009;88(1):67-71.
2009: Mathias Witzens-Harig; Monika Reiz; Christiane Heiss; Axel Benner; Manfred Hensel; Kai Neben; Peter Dreger; Alwin Kraemer; Anthony Ho
Quality of life during maintenance therapy with the anti-CD20 antibody rituximab in patients with B cell non-Hodgkin's lymphoma: results of a prospective randomized controlled trial.
Annals of hematology 2009;88(1):51-7.
2007: Christian M Zechmann; Frederik Giesel; Jens Hillengass; Amit Mehndiratta; Kai Neben; Stefan Delorme; Thomas Moehler
Where is the primary tumour?
Lancet 2007;370(9601):1800.
2007: Manfred Hensel; Martin Zoz; Christian Giesecke; Axel Benner; Kai Neben; Anna Jauch; Stephan Stilgenbauer; Anthony Ho; Alwin Krämer
High rate of centrosome aberrations and correlation with proliferative activity in patients with untreated B-cell chronic lymphocytic leukemia.
International journal of cancer. Journal international du cancer 2007;121(5):978-83.
2007: Björn Tews; Peter Roerig; Christian Hartmann; Meinhard Hahn; Jörg Felsberg; Britta Blaschke; Michael S Sabel; Annegret Kunitz; Grischa Toedt; Kai Neben; Axel Benner; A von Deimling; Guido Reifenberger; Peter Lichter
Hypermethylation and transcriptional downregulation of the CITED4 gene at 1p34.2 in oligodendroglial tumours with allelic losses on 1p and 19q.
Oncogene 2007;26(34):5010-6.
2007: Kai Neben; German Ott; Silja Schweizer; Jörg Kalla; Björn Tews; Tiemo Katzenberger; Meinhard Hahn; Andreas Rosenwald; Anthony Ho; Hans Konrad Müller-Hermelink; Peter Lichter; Alwin Krämer
Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma.
International journal of cancer. Journal international du cancer 2007;120(8):1669-77.
2006: Björn Tews; Jörg Felsberg; Christian Hartmann; Annegret Kunitz; Meinhard Hahn; Grischa Toedt; Kai Neben; Lars Hummerich; Andreas von Deimling; Guido Reifenberger; Peter Lichter
Identification of novel oligodendroglioma-associated candidate tumor suppressor genes in 1p36 and 19q13 using microarray-based expression profiling.
International journal of cancer. Journal international du cancer 2006;119(4):792-800.
2005: Frank Mendrzyk; Bernhard Radlwimmer; Stefan Joos; Felix Kokocinski; Axel Benner; Daniel E Stange; Kai Neben; Heike Fiegler; Nigel P Carter; Guido Reifenberger; Andrey Korshunov; Peter Lichter
Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(34):8853-62.
2005: Alwin Krämer; Kai Neben; Anthony D Ho
Centrosome aberrations in hematological malignancies.
Cell biology international 2005;29(5):375-83.
2005: Gunnar Wrobel; Peter Roerig; Felix Kokocinski; Kai Neben; Meinhard Hahn; Guido Reifenberger; Peter Lichter
Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression.
International journal of cancer. Journal international du cancer 2005;114(2):249-56.
2005: Kai Neben; Susanne Schnittger; Benedikt Brors; Björn Tews; Felix Kokocinski; Torsten Haferlach; Jasmin Müller; Meinhard Hahn; Wolfgang Hiddemann; Roland Eils; Peter Lichter; Claudia Schoch
Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype.
Oncogene 2005;24(9):1580-8.
2004: Klaus Wasser; Thomas Moehler; Kai Neben; S Nosas; J Heiss; Hartmut Goldschmidt; Jens Hillengass; Christoph Düber; Hans-Ulrich Kauczor; Stefan Delorme
[Dynamic MRI of the bone marrow for monitoring multiple myeloma during treatment with thalidomide as monotherapy or in combination with CED chemotherapy].
RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 2004;176(9):1285-95.
2004: Mathias Witzens; Thomas Moehler; Kai Neben; Stefan Fruehauf; Wolfgang Hartschuh; Anthony Ho; Hartmut Goldschmidt
Development of leukocytoclastic vasculitis in a patient with multiple myeloma during treatment with thalidomide.
Annals of hematology 2004;83(7):467-70.
2004: Kai Neben; Andrey Korshunov; Axel Benner; Gunnar Wrobel; Meinhard Hahn; Felix Kokocinski; Andrey Golanov; Stefan Joos; Peter Lichter
Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival.
Cancer research 2004;64(9):3103-11.
2004: Kai Neben; Björn Tews; Gunnar Wrobel; Meinhard Hahn; Felix Kokocinski; Christian Giesecke; Ulf Krause; Anthony Ho; Alwin Krämer; Peter Lichter
Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes.
Oncogene 2004;23(13):2379-84.
2004: B Kasper; Thomas Moehler; Kai Neben; A D Ho; H Goldschmidt
Combination therapy of Thalidomide and Peginterferon in patients with progressive multiple myeloma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(1):176-7.
2003: Andreas Schneeweiss; Hans-Peter Sinn; Volker Ehemann; Tanja Khbeis; Kai Neben; Ulf Krause; Anthony Ho; Gunther Bastert; Alwin Krämer
Centrosomal aberrations in primary invasive breast cancer are associated with nodal status and hormone receptor expression.
International journal of cancer. Journal international du cancer 2003;107(3):346-52.
2003: Andrey Korshunov; Kai Neben; Gunnar Wrobel; Björn Tews; Axel Benner; Meinhard Hahn; Andrey Golanov; Peter Lichter
Gene expression patterns in ependymomas correlate with tumor location, grade, and patient age.
The American journal of pathology 2003;163(5):1721-7.
2003: Alwin Krämer; Silja Schweizer; Kai Neben; Christian Giesecke; Jörg Kalla; Tiemo Katzenberger; Axel Benner; Hans Konrad Müller-Hermelink; Anthony Ho; German Ott
Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma.
Leukemia 2003;17(11):2207-13.
2003: Kai Neben; Christian Giesecke; Silja Schweizer; Anthony Ho; Alwin Krämer
Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile.
Blood 2003;101(1):289-91.
2002: Kai Neben; Thomas Moehler; Axel Benner; Alwin Kraemer; Gerlinde Egerer; Anthony Ho; Hartmut Goldschmidt
Dose-dependent effect of thalidomide on overall survival in relapsed multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3377-82.
2002: Kai Neben; Joannis Mytilineos; Thomas Moehler; Astrid Preiss; Alwin Kraemer; Anthony Ho; Gerhard Opelz; Hartmut Goldschmidt
Polymorphisms of the tumor necrosis factor-alpha gene promoter predict for outcome after thalidomide therapy in relapsed and refractory multiple myeloma.
Blood 2002;100(6):2263-5.
2002: Alwin Krämer; Kai Neben; Anthony Ho
Centrosome replication, genomic instability and cancer.
Leukemia 2002;16(5):767-75.
2001: Thomas Moehler; Kai Neben; Axel Benner; Gerlinde Egerer; Fatime Krasniqi; Anthony Ho; Hartmut Goldschmidt
Salvage therapy for multiple myeloma with thalidomide and CED chemotherapy.
Blood 2001;98(13):3846-8.
2001: Thomas Moehler; Kai Neben; Anthony Ho; Hartmut Goldschmidt
Angiogenesis in hematologic malignancies.
Annals of hematology 2001;80(12):695-705.
2001: Kai Neben; Thomas Moehler; Alwin Kraemer; Axel Benner; Gerlinde Egerer; Anthony Ho; Hartmut Goldschmidt
Response to thalidomide in progressive multiple myeloma is not mediated by inhibition of angiogenic cytokine secretion.
British journal of haematology 2001;115(3):605-8.
2001: Kai Neben; M Werner; Ludger Bernd; Volker Ewerbeck; Günter Delling; Anthony Ho
A man with hereditary exostoses and high-grade non-Hodgkin's lymphoma of the bone.
Annals of hematology 2001;80(11):682-4.
2001: Kai Neben; Thomas Moehler; Gerlinde Egerer; Alwin Kraemer; Jens Hillengass; Axel Benner; Anthony Ho; Hartmut Goldschmidt
High plasma basic fibroblast growth factor concentration is associated with response to thalidomide in progressive multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2675-81.
2001: Thomas Moehler; Hans Hawighorst; Kai Neben; Gerlinde Egerer; Jens Hillengass; Regina Max; Axel Benner; Anthony Ho; Gerhard van Kaick; Hartmut Goldschmidt
Bone marrow microcirculation analysis in multiple myeloma by contrast-enhanced dynamic magnetic resonance imaging.
International journal of cancer. Journal international du cancer 2001;93(6):862-8.
2000: Kai Neben; Stefan Hohaus; Hartmut Goldschmidt; Gerlinde Egerer; Maria Teresa Voso; Anthony Ho; Rainer Haas
High-dose therapy with peripheral blood stem cell transplantation for patients with relapsed or refractory Hodgkin's disease: long-term outcome and prognostic factors.
Annals of hematology 2000;79(10):547-55.
2000: Thomas Moehler; Hans Hawighorst; Kai Neben; Gerlinde Egerer; Axel Benner; Jens Hillengass; Regina Max; Anthony Ho; Hartmut Goldschmidt; Gerhard van Kaick
[Functional magnetic resonance tomography in the diagnosis and therapy monitoring in multiple myeloma].
Der Radiologe 2000;40(8):723-30.