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Angel Nebreda

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Phenomena

Phosphorylation

Chemicals & Drugs

Physiology

Living Beings

Anatomy

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Genes & Molecular Sequences

Amino Acid Sequence

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Co-Publications
Name
7
Cuadrado, Ana
7
Dolado, Ignacio
7
Perdiguero, Eusebio
6
Ferby, Ingvar
6
Ambrosino, Concetta
5
Cohen, Philip
4
Gavin, Anne-Claude
4
Perez, Laurent
4
Porras, Almudena
3
Schmitt, Anja
3
Palmer, A
3
Platanias, Leonidas
3
Swat, Aneta
3
Zuluaga, Susana
3
Cheung, Peter

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Publications

TOP 3
Cuadrado Myriam; Gutierrez-Martinez Paula; Swat Aneta; Nebreda Angel R; Fernandez-Capetillo Oscar
p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage.
Dinarina Ana; Santamaria Patricia G; Nebreda Angel R
Cell cycle regulation of the mammalian CDK activator RINGO/Speedy A.
Wagner Erwin F; Nebreda Angel R
Signal integration by JNK and p38 MAPK pathways in cancer development.

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All Publications

2009: Cuadrado Myriam; Gutierrez-Martinez Paula; Swat Aneta; Nebreda Angel R; Fernandez-Capetillo Oscar
p27Kip1 stabilization is essential for the maintenance of cell cycle arrest in response to DNA damage.
Cancer research 2009;69(22):8726-32.
2009: Dinarina Ana; Santamaria Patricia G; Nebreda Angel R
Cell cycle regulation of the mammalian CDK activator RINGO/Speedy A.
FEBS letters 2009;583(17):2772-8.
2009: Wagner Erwin F; Nebreda Angel R
Signal integration by JNK and p38 MAPK pathways in cancer development.
Nature reviews. Cancer 2009;9(8):537-49.
2009: Lafarga Vanesa; Cuadrado Ana; Lopez de Silanes Isabel; Bengoechea Rocio; Fernandez-Capetillo Oscar; Nebreda Angel R
p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint.
Molecular and cellular biology 2009;29(16):4341-51.
2009: Git Anna; Allison Rachel; Perdiguero Eusebio; Nebreda Angel R; Houliston Evelyn; Standart Nancy
Vg1RBP phosphorylation by Erk2 MAP kinase correlates with the cortical release of Vg1 mRNA during meiotic maturation of Xenopus oocytes.
RNA (New York, N.Y.) 2009;15(6):1121-33.
2009: Swat Aneta; Dolado Ignacio; Rojas Jose Maria; Nebreda Angel R
Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38alpha mitogen-activated protein kinase via Sprouty2 downregulation.
Molecular and cellular biology 2009;29(12):3332-43.
2009: Cuenda Ana; Nebreda Angel R
p38delta and PKD1: kinase switches for insulin secretion.
Cell 2009;136(2):209-10.
2008: Dolado Ignacio; Nebreda Angel R
AKT and oxidative stress team up to kill cancer cells.
Cancer cell 2008;14(6):427-9.
2008: Ruiz E Josué; Hunt Tim; Nebreda Angel R
Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation.
Molecular cell 2008;32(2):210-20.
2008: Heinrichsdorff Jan; Luedde Tom; Perdiguero Eusebio; Nebreda Angel R; Pasparakis Manolis
p38 alpha MAPK inhibits JNK activation and collaborates with IkappaB kinase 2 to prevent endotoxin-induced liver failure.
EMBO reports 2008;9(10):1048-54.
2008: Jagemann Lucas R; Pérez-Rivas Luís G; Ruiz E Josué; Ranea Juan A; Sánchez-Jiménez Francisca; Nebreda Angel R; Alba Emilio; Lozano José
The functional interaction of 14-3-3 proteins with the ERK1/2 scaffold KSR1 occurs in an isoform-specific manner.
The Journal of biological chemistry 2008;283(25):17450-62.
2008: Dinarina Ana; Ruiz E Josué; O'Loghlen Ana; Mouron Silvana; Perez Laurent; Nebreda Angel R
Negative regulation of cell-cycle progression by RINGO/Speedy E.
The Biochemical journal 2008;410(3):535-42.
2007: Lafarga Vanesa; Cuadrado Ana; Nebreda Angel R
p18(Hamlet) mediates different p53-dependent responses to DNA-damage inducing agents.
Cell cycle (Georgetown, Tex.) 2007;6(19):2319-22.
2007: Cuadrado Ana; Nebreda Angel R
New insights into RSK activation and hematopoietic cancer.
Cancer cell 2007;12(3):187-9.
2007: Zuluaga Susana; Gutiérrez-Uzquiza Alvaro; Bragado Paloma; Alvarez-Barrientos Alberto; Benito Manuel; Nebreda Angel R; Porras Almudena
p38alpha MAPK can positively or negatively regulate Rac-1 activity depending on the presence of serum.
FEBS letters 2007;581(20):3819-25.
2007: Casado-Vela Juan; Ruiz Edgar J; Nebreda Angel R; Casal J Ignacio
A combination of neutral loss and targeted product ion scanning with two enzymatic digestions facilitates the comprehensive mapping of phosphorylation sites.
Proteomics 2007;7(15):2522-9.
2007: Ventura Juan José; Tenbaum Stephan; Perdiguero Eusebio; Huth Marion; Guerra Carmen; Barbacid Mariano; Pasparakis Manolis; Nebreda Angel R
p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation.
Nature genetics 2007;39(6):750-8.
2007: Cuadrado Ana; Lafarga Vanesa; Cheung Peter C F; Dolado Ignacio; Llanos Susana; Cohen Philip; Nebreda Angel R
A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis.
The EMBO journal 2007;26(8):2115-26.
2007: Meissner Joachim D; Chang Kin-Chow; Kubis Hans-Peter; Nebreda Angel R; Gros Gerolf; Scheibe Renate J
The p38alpha/beta mitogen-activated protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes.
The Journal of biological chemistry 2007;282(10):7265-75.
2007: Dolado Ignacio; Swat Aneta; Ajenjo Nuria; De Vita Gabriella; Cuadrado Ana; Nebreda Angel R
p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.
Cancer cell 2007;11(2):191-205.
2007: Zuluaga Susana; Alvarez-Barrientos Alberto; Gutiérrez-Uzquiza Alvaro; Benito Manuel; Nebreda Angel R; Porras Almudena
Negative regulation of Akt activity by p38alpha MAP kinase in cardiomyocytes involves membrane localization of PP2A through interaction with caveolin-1.
Cellular signalling 2007;19(1):62-74.
2006: Rousseau Simon; Dolado Ignacio; Beardmore Victoria; Shpiro Natalia; Marquez Rudolfo; Nebreda Angel R; Arthur J Simon C; Case Lauren M; Tessier-Lavigne Marc; Gaestel Matthias; Cuenda Ana; Cohen Philip
CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway.
Cellular signalling 2006;18(11):1897-905.
2006: Gutierrez Gustavo J; Vögtlin Andrea; Castro Ana; Ferby Ingvar; Salvagiotto Giorgia; Ronai Ze'ev; Lorca Thierry; Nebreda Angel R
Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation.
Nature cell biology 2006;8(10):1084-94.
2006: Lemaire Matthieu; Froment Carine; Boutros Rose; Mondesert Odile; Nebreda Angel R; Monsarrat Bernard; Ducommun Bernard
CDC25B phosphorylation by p38 and MK-2.
Cell cycle (Georgetown, Tex.) 2006;5(15):1649-53.
2006: Giafis Nick; Katsoulidis Efstratios; Sassano Antonella; Tallman Martin S; Higgins Linda S; Nebreda Angel R; Davis Roger J; Platanias Leonidas C
Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses.
Cancer research 2006;66(13):6763-71.
2006: Ambrosino Concetta; Iwata Tomoko; Scafoglio Claudio; Mallardo Massimo; Klein Rüdiger; Nebreda Angel R
TEF-1 and C/EBPbeta are major p38alpha MAPK-regulated transcription factors in proliferating cardiomyocytes.
The Biochemical journal 2006;396(1):163-72.
2006: Alfonso Patricia; Dolado Ignacio; Swat Aneta; Núñez Antonio; Cuadrado Ana; Nebreda Angel R; Casal J Ignacio
Proteomic analysis of p38alpha mitogen-activated protein kinase-regulated changes in membrane fractions of RAS-transformed fibroblasts.
Proteomics 2006;6 Suppl 1():S262-71.
2006: Nebreda Angel R
CDK activation by non-cyclin proteins.
Current opinion in cell biology 2006;18(2):192-8.
2006: Ventura Juan-José; Nebreda Angel R
Protein kinases and phosphatases as therapeutic targets in cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2006;8(3):153-60.
2006: Lluís Frederic; Perdiguero Eusebio; Nebreda Angel R; Muñoz-Cánoves Pura
Regulation of skeletal muscle gene expression by p38 MAP kinases.
Trends in cell biology 2006;16(1):36-44.
2005: Faust Dagmar; Dolado Ignacio; Cuadrado Ana; Oesch Franz; Weiss Carsten; Nebreda Angel R; Dietrich Cornelia
p38alpha MAPK is required for contact inhibition.
Oncogene 2005;24(53):7941-5.
2005: Rousseau Simon; Peggie Mark; Campbell David G; Nebreda Angel R; Cohen Philip
Nogo-B is a new physiological substrate for MAPKAP-K2.
The Biochemical journal 2005;391(Pt 2):433-40.
2005: Macé Gaëtane; Miaczynska Marta; Zerial Marino; Nebreda Angel R
Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis.
The EMBO journal 2005;24(18):3235-46.
2005: Emerling Brooke M; Platanias Leonidas C; Black Emma; Nebreda Angel R; Davis Roger J; Chandel Navdeep S
Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling.
Molecular and cellular biology 2005;25(12):4853-62.
2005: Dinarina Ana; Perez Laurent H; Davila Amparo; Schwab Markus; Hunt Tim; Nebreda Angel R
Characterization of a new family of cyclin-dependent kinase activators.
The Biochemical journal 2005;386(Pt 2):349-55.
2004: Perdiguero Eusebio; Nebreda Angel R
Regulation of Cdc25C activity during the meiotic G2/M transition.
Cell cycle (Georgetown, Tex.) 2004;3(6):733-7.
2004: Cheung Peter C F; Nebreda Angel R; Cohen Philip
TAB3, a new binding partner of the protein kinase TAK1.
The Biochemical journal 2004;378(Pt 1):27-34.
2004: Porras Almudena; Zuluaga Susana; Black Emma; Valladares Amparo; Alvarez Alberto M; Ambrosino Concetta; Benito Manuel; Nebreda Angel R
P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli.
Molecular biology of the cell 2004;15(2):922-33.
2004: Suelves Mònica; Lluís Frederic; Ruiz Vanessa; Nebreda Angel R; Muñoz-Cánoves Pura
Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes.
The EMBO journal 2004;23(2):365-75.
2004: Li Yongzhong; Sassano Antonella; Majchrzak Beata; Deb Dilip K; Levy David E; Gaestel Matthias; Nebreda Angel R; Fish Eleanor N; Platanias Leonidas C
Role of p38alpha Map kinase in Type I interferon signaling.
The Journal of biological chemistry 2004;279(2):970-9.
2004: Perdiguero Eusebio; Nebreda Angel R
Use of Xenopus oocytes and early embryos to study MAPK signaling.
Methods in molecular biology (Clifton, N.J.) 2004;250():299-314.
2003: Cheung Peter C F; Campbell David G; Nebreda Angel R; Cohen Philip
Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha.
The EMBO journal 2003;22(21):5793-805.
2003: Perdiguero Eusebio; Pillaire Marie-Jeanne; Bodart Jean-Francois; Hennersdorf Florian; Frödin Morten; Duesbery Nicholas S; Alonso Gema; Nebreda Angel R
Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.
The EMBO journal 2003;22(21):5746-56.
2003: Merckx Anaïs; Le Roch Karine; Nivez Marie-Paule; Dorin Dominique; Alano Pietro; Gutierrez Gustavo J; Nebreda Angel R; Goldring Dean; Whittle Christina; Patterson Shelley; Chakrabarti Debopam; Doerig Christian
Identification and initial characterization of three novel cyclin-related proteins of the human malaria parasite Plasmodium falciparum.
The Journal of biological chemistry 2003;278(41):39839-50.
2003: Biondi Ricardo M; Nebreda Angel R
Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions.
The Biochemical journal 2003;372(Pt 1):1-13.
2003: Ambrosino Concetta; Mace Gaetane; Galban Stefanie; Fritsch Cornelius; Vintersten Kristina; Black Emma; Gorospe Myriam; Nebreda Angel R
Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen-activated protein kinase.
Molecular and cellular biology 2003;23(1):370-81.
2002: Perez Laurent H; Antonio Celia; Flament Stéphane; Vernos Isabelle; Nebreda Angel R
Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes.
Nature cell biology 2002;4(10):737-42.
2002: Ramsauer Katrin; Sadzak Iwona; Porras Almudena; Pilz Andreas; Nebreda Angel R; Decker Thomas; Kovarik Pavel
p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12859-64.
2002: Schmitt Anja; Nebreda Angel R
Signalling pathways in oocyte meiotic maturation.
Journal of cell science 2002;115(Pt 12):2457-9.
2002: Bulavin Dmitry V; Demidov Oleg N; Saito Shin'ichi; Kauraniemi Paivikki; Phillips Crissy; Amundson Sally A; Ambrosino Concetta; Sauter Guido; Nebreda Angel R; Anderson Carl W; Kallioniemi Anne; Fornace Albert J; Appella Ettore
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity.
Nature genetics 2002;31(2):210-5.
2002: Schmitt Anja; Gutierrez Gustavo J; Lénárt Péter; Ellenberg Jan; Nebreda Angel R
Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation.
FEBS letters 2002;518(1-3):23-8.
2002: Bodart Jean-Francois L; Gutierrez Davina V; Nebreda Angel R; Buckner Bree D; Resau James R; Duesbery Nicholas S
Characterization of MPF and MAPK activities during meiotic maturation of Xenopus tropicalis oocytes.
Developmental biology 2002;245(2):348-61.
2002: Riechmann Veit; Gutierrez Gustavo J; Filardo Paolo; Nebreda Angel R; Ephrussi Anne
Par-1 regulates stability of the posterior determinant Oskar by phosphorylation.
Nature cell biology 2002;4(5):337-42.
2002: Schmitt Anja; Nebreda Angel R
Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4361-6.
2001: Terret M E; Ferby I; Nebreda A R; Verlhac M H
RINGO efficiently triggers meiosis resumption in mouse oocytes and induces cell cycle arrest in embryos.
Biology of the cell / under the auspices of the European Cell Biology Organization 2001;93(1-2):89-97.
2001: Ambrosino C; Nebreda A R
Cell cycle regulation by p38 MAP kinases.
Biology of the cell / under the auspices of the European Cell Biology Organization 2001;93(1-2):47-51.
2001: Karaiskou A; Perez L H; Ferby I; Ozon R; Jessus C; Nebreda A R
Differential regulation of Cdc2 and Cdk2 by RINGO and cyclins.
The Journal of biological chemistry 2001;276(38):36028-34.
2000: Nebreda A R; Ferby I
Regulation of the meiotic cell cycle in oocytes.
Current opinion in cell biology 2000;12(6):666-75.
2000: Alonso G; Ambrosino C; Jones M; Nebreda A R
Differential activation of p38 mitogen-activated protein kinase isoforms depending on signal strength.
The Journal of biological chemistry 2000;275(51):40641-8.
2000: Pillaire M J; Nebreda A R; Darbon J M
Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38gamma in human melanoma cells.
Biochemical and biophysical research communications 2000;278(3):724-8.
2000: Antonio C; Ferby I; Wilhelm H; Jones M; Karsenti E; Nebreda A R; Vernos I
Xkid, a chromokinesin required for chromosome alignment on the metaphase plate.
Cell 2000;102(4):425-35.
2000: Adams R H; Porras A; Alonso G; Jones M; Vintersten K; Panelli S; Valladares A; Perez L; Klein R; Nebreda A R
Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development.
Molecular cell 2000;6(1):109-16.
2000: Nebreda A R; Porras A
p38 MAP kinases: beyond the stress response.
Trends in biochemical sciences 2000;25(6):257-60.
2000: Palmer A; Nebreda A R
The activation of MAP kinase and p34cdc2/cyclin B during the meiotic maturation of Xenopus oocytes.
Progress in cell cycle research 2000;4():131-43.
1999: Nebreda A R; Gavin A C
Perspectives: signal transduction. Cell survival demands some Rsk.
Science (New York, N.Y.) 1999;286(5443):1309-10.
1999: Gavin A C; Ni Ainle A; Chierici E; Jones M; Nebreda A R
A p90(rsk) mutant constitutively interacting with MAP kinase uncouples MAP kinase from p34(cdc2)/cyclin B activation in Xenopus oocytes.
Molecular biology of the cell 1999;10(9):2971-86.
1999: Ferby I; Blazquez M; Palmer A; Eritja R; Nebreda A R
A novel p34(cdc2)-binding and activating protein that is necessary and sufficient to trigger G(2)/M progression in Xenopus oocytes.
Genes & development 1999;13(16):2177-89.
1999: Gavin A C; Nebreda A R
A MAP kinase docking site is required for phosphorylation and activation of p90(rsk)/MAPKAP kinase-1.
Current biology : CB 1999;9(5):281-4.
1999: Dorey K; Barilá D; Gavin A C; Nebreda A R; Superti-Furga G
Regulation of human c-Abl tyrosine kinase activity in Xenopus oocytes and acceleration of progesterone-induced G2/M transition by oncogenic forms.
Biological chemistry 1999;380(2):223-30.
1998: Palmer A; Gavin A C; Nebreda A R
A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1.
The EMBO journal 1998;17(17):5037-47.

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