FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jacques Neefjes

Research Profile

Physiology

Chemicals & Drugs

Anatomy

Co-author Network

Publications

TOP 3
Jacques Neefjes; Emil R Unanue
The ever surprising field of antigen presentation.
Malgorzata A Garstka; Jacques Neefjes
How to target MHC class II into the MIIC compartment.
Ruud H Wijdeven; Petra Paul; Jeroen M Bakker; Jacques Neefjes
Exploring genome-wide datasets of MHC class II antigen presentation.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jacques Neefjes (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Jacques Neefjes; Emil R Unanue
The ever surprising field of antigen presentation.
Molecular immunology 2013;55(2):105.
2013: Malgorzata A Garstka; Jacques Neefjes
How to target MHC class II into the MIIC compartment.
Molecular immunology 2013;55(2):162-5.
2013: Ruud H Wijdeven; Petra Paul; Jeroen M Bakker; Jacques Neefjes
Exploring genome-wide datasets of MHC class II antigen presentation.
Molecular immunology 2013;55(2):172-4.
2013: Coenraad Kuijl; Jacques Neefjes; Manohar Pilli; Richard H Scheller; Suresh K Alahari; Monica Calero; Karen E Ervin; Hans Janssen; Sobhanaditya Jonnalagadda; Poh-Sim Khoo; Jagath R Junutula
Rac and Rab GTPases dual effector Nischarin regulates vesicle maturation to facilitate survival of intracellular bacteria.
The EMBO journal 2013;32(5):713-27.
2013: Bert van de Kooij; Inge Verbrugge; Evert de Vries; Merel Gijsen; Chiel Maas; Veronica Montserrat; Jacques Neefjes; Jannie Borst
Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.
The Journal of biological chemistry 2013;288(9):6617-28.
2013: Reggy Ekkebus; Paul P Geurink; Soenita Goerdayal; Albert J R Heck; David Komander; Yogesh Kulathu; Jacques Neefjes; Ilana Berlin; Annemieke de Jong; Arjen Scholten; Sander I van Kasteren; Huib Ovaa
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases.
Journal of the American Chemical Society 2013;135(8):2867-70.
2013: Victoria Menendez-Benito; Marina Roy-Luzarraga; Sjoerd J van Deventer; F van Leeuwen; Victor Jimenez-Garcia; Jacques Neefjes
Spatiotemporal analysis of organelle and macromolecular complex inheritance.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(1):175-80.
2013: Petra Paul; Jacques Neefjes
Studying MHC class II transport in dendritic cells.
Methods in molecular biology (Clifton, N.J.) 2013;960():489-507.
2013: Marlieke L M Jongsma; Jacques Neefjes
Assaying peptide translocation by the peptide transporter TAP.
Methods in molecular biology (Clifton, N.J.) 2013;960():53-65.
2012: Sidong Huang; Theo Knijnenburg; Ultan McDermott; Lorenza Mittempergher; Jacques Neefjes; Wouter Nijkamp; Anirudh Prahallad; Paul Roepman; Ramon Salazar; Andreas Schlicker; Chong Sun; Fumihiro Tanaka; Peter ten Dijke; Hidetaka Uramoto; Lodewyk F A Wessels; Mathew Garnett; Wipawadee Grernrum; Floris H Groenendijk; Michael Hölzel; Roderick L Beijersbergen; René Bernards
MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling.
Cell 2012;151(5):937-50.
2012: Kristiina Uusi-Rauva; Rik van der Kant; Jouni Vesa; Aija Kyttälä; Jacques Neefjes; Vesa M Olkkonen; Kimmo Tanhuanpää; Anu Jalanko
Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments.
Cellular and molecular life sciences : CMLS 2012;69(12):2075-89.
2012: Dušana Majera; Jacques Neefjes; Dušan Turk; Katarina Črnigoj Kristan; Marko Mihelič
Expression, purification and assembly of soluble multimeric MHC class II-invariant chain complexes.
FEBS letters 2012;586(9):1318-24.
2012: René Houtman; John W M Martens; Diana Melchers; Jacques Neefjes; Mariska Rondaij; Rob Ruijtenbeek; Desiree Verwoerd; Renée de Leeuw; Rob Michalides
Serine-305 phosphorylation modulates estrogen receptor alpha binding to a coregulator peptide array, with potential application in predicting responses to tamoxifen.
Molecular cancer therapeutics 2012;11(4):805-16.
2012: Robbert M Spaapen; Jacques Neefjes
Immuno-waste exposure and further management.
Nature immunology 2012;13(2):109-11.
2012: Tineke van den Hoorn; Petra Paul; Hans Janssen; Lennert Janssen; Jacques Neefjes
Dynamics within tetraspanin pairs affect MHC class II expression.
Journal of cell science 2012;125(Pt 2):328-39.
2012: Yuri Souwer; Elena Zagato; Yotam E Bar-Ephraïm; Jelle de Wit; Alexander Griekspoor; Hans Janssen; Tineke Jorritsma; Chiara Martinoli; Jacques Neefjes; Maria Rescigno; S Marieke Van Ham
Selective infection of antigen-specific B lymphocytes by Salmonella mediates bacterial survival and systemic spreading of infection.
PloS one 2012;7(11):e50667.
2012: Jacques Neefjes; Charlotte Sadaka
Into the intracellular logistics of cross-presentation.
Frontiers in immunology 2012;3():31.
2011: Jacques Neefjes; Petra Paul; Marlieke L M Jongsma; Oddmund Bakke
Towards a systems understanding of MHC class I and MHC class II antigen presentation.
Nature reviews. Immunology 2011;11(12):823-36.
2011: Frederik J Verweij; Monique van Eijndhoven; Erik S Hopmans; Tineke Vendrig; Tom Wurdinger; Ellen Cahir-McFarland; Elliott Kieff; Dirk Geerts; Rik van der Kant; Jacques Neefjes; Jaap Middeldorp; D Michiel Pegtel
LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation.
The EMBO journal 2011;30(11):2115-29.
2011: Petra Paul; Tineke van den Hoorn; Marlieke L M Jongsma; Mark J Bakker; Rutger Hengeveld; Lennert Janssen; Peter Cresswell; David A Egan; Marieke van Ham; Anja Ten Brinke; Huib Ovaa; Roderick L Beijersbergen; Coenraad Kuijl; Jacques Neefjes
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation.
Cell 2011;145(2):268-83.
2011: Tineke van den Hoorn; Petra Paul; Marlieke L M Jongsma; Jacques Neefjes
Routes to manipulate MHC class II antigen presentation.
Current opinion in immunology 2011;23(1):88-95.
2011: Renée de Leeuw; Jacques Neefjes; Rob Michalides
A role for estrogen receptor phosphorylation in the resistance to tamoxifen.
International journal of breast cancer 2011;2011():232435.
2011: Jan H. Kessler; Selina Khan; Ulrike Seifert; Sylvie Le Gall; K Martin Chow; Annette Paschen; Sandra A Bres-Vloemans; Arnoud de Ru; Nadine van Montfoort; Kees L M C Franken; Willemien E Benckhuijsen; Jill M Brooks; Thorbald van Hall; Kallol Ray; Arend Mulder; Ilias I N Doxiadis; Paul F van Swieten; Hermen S Overkleeft; Annik Prat; Birgitta Tomkinson; Jacques Neefjes; Peter M Kloetzel; David W Rodgers; Louis B Hersh; Jan W Drijfhout; Peter A van Veelen; Ferry Ossendorp; Cornelis J M Melief
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes.
Nature immunology 2011;12(1):45-53.
2011: Marleen Kok; Wilbert Zwart; Caroline Holm; Renske Fles; Michael Hauptmann; Laura J van't Veer; Lodewyk F A Wessels; Jacques Neefjes; Olle Stål; Sabine C Linn; Göran Landberg; Rob Michalides
PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer.
Breast cancer research and treatment 2011;125(1):1-12.
2010: Wilbert Zwart; Victor Peperzak; Evert de Vries; Anna M Keller; Gerda van der Horst; Elise A M Veraar; Ulf Geumann; Hans Janssen; Lennert Janssen; Shalin Naik; Jacques Neefjes; Jannie Borst
The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells.
Journal of cell science 2010;123(Pt 21):3817-27.
2010: Sjoerd van Deventer; Jacques Neefjes
The Immunoproteasome Cleans up after Inflammation.
Cell 2010;142(4):517-8.
2010: Baoxu Pang; Jacques Neefjes
Coupled for cross-presentation in tumor immunotherapy.
Science translational medicine 2010;2(44):44ps40.
2010: Wilbert Zwart; Renée de Leeuw; Mariska Rondaij; Jacques Neefjes; Michael A Mancini; Rob Michalides
The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.
Journal of cell science 2010;123(Pt 8):1253-61.
2010: Kitty F Verzijlbergen; Victoria Menendez-Benito; Tibor van Welsem; Sjoerd J van Deventer; Derek L Lindstrom; Huib Ovaa; Jacques Neefjes; Daniel E Gottschling; F van Leeuwen
Recombination-induced tag exchange to track old and new proteins.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):64-8.
2010: Izhar Salomon; Hans Janssen; Jacques Neefjes
Mechanical forces used for cell fractionation can create hybrid membrane vesicles.
International journal of biological sciences 2010;6(7):649-54.
2010: Jelle de Wit; Yuri Souwer; Tineke Jorritsma; Hanny Klaasse Bos; Anja ten Brinke; Jacques Neefjes; S Marieke Van Ham
Antigen-specific B cells reactivate an effective cytotoxic T cell response against phagocytosed Salmonella through cross-presentation.
PloS one 2010;5(9):e13016.
2009: Wilbert Zwart; Mariska Rondaij; Kees Jalink; Zelton Sharp; Michael A Mancini; Jacques Neefjes; Rob Michalides
Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.
Molecular endocrinology (Baltimore, Md.) 2009;23(9):1335-45.
2009: Coenraad Kuijl; Jacques Neefjes
New insight into the everlasting host-pathogen arms race.
Nature immunology 2009;10(8):808-9.
2009: Baoxu Pang; Joost Neijssen; Xiaohang Qiao; Lennert Janssen; Hans Janssen; Christoph Lippuner; Jacques Neefjes
Direct antigen presentation and gap junction mediated cross-presentation during apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(2):1083-90.
2009: Nuno Rocha; Coenraad Kuijl; Rik van der Kant; Lennert Janssen; Diane Houben; Hans Janssen; Wilbert Zwart; Jacques Neefjes
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.
The Journal of cell biology 2009;185(7):1209-25.
2009: Yuri Souwer; Alexander Griekspoor; Tineke Jorritsma; Jelle de Wit; Hans Janssen; Jacques Neefjes; S Marieke Van Ham
B cell receptor-mediated internalization of salmonella: a novel pathway for autonomous B cell activation and antibody production.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7473-81.
2009: Houssem Benlalam; Abdelali JALIL; Meriem Hasmim; Baoxu Pang; Ryad Tamouza; Michèle Mitterrand; yann godet; Nathalie Lamerant; Caroline Robert; Marie-Françoise Avril; Jacques Neefjes; Thomas Tursz; Fathia Mami-Chouaib; Claudine Kieda; Salem Chouaib
Gap junction communication between autologous endothelial and tumor cells induce cross-recognition and elimination by specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):2654-64.
2008: Tineke van den Hoorn; Jacques Neefjes
Activated pDCs: open to new antigen-presentation possibilities.
Nature immunology 2008;9(11):1208-10.
2008: James W Hodge; Jacques Neefjes; Chandan Guha; James L Gulley
Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges.
Oncology (Williston Park, N.Y.) 2008;22(9):1064-70; discussion 1075, 1080-1, 1084.
2008: Danijela Koppers-Lalic; Marieke C Verweij; Andrea D Lipińska; Ying Wang; Edwin Quinten; Eric Reits; Joachim Koch; Sandra Loch; Marisa Marcondes Rezende; Franz Daus; Krystyna Bieńkowska-Szewczyk; Nikolaus Osterrieder; Thomas C Mettenleiter; Mirjam H M Heemskerk; Robert Tampé; Jacques Neefjes; Shafiqul I Chowdhury; Maaike E Ressing; F A M Rijsewijk; Emmanuel J H J Wiertz
Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP.
PLoS pathogens 2008;4(5):e1000080.
2008: Charles F Towne; Ian A York; Joost Neijssen; Margaret L Karow; Andrew J Murphy; David M Valenzuela; George D Yancopoulos; Jacques Neefjes; Kenneth L Rock
Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1704-12.
2008: Nuno Rocha; Jacques Neefjes
MHC class II molecules on the move for successful antigen presentation.
The EMBO journal 2008;27(1):1-5.
2007: Coenraad Kuijl; Nigel D L Savage; Marije Marsman; Adriaan W Tuin; Lennert Janssen; David A Egan; Mirjam Ketema; Rian van den Nieuwendijk; Susan J F van den Eeden; Annemieke Geluk; Alex Poot; Gijsbert A van der Marel; Roderick L Beijersbergen; Herman S Overkleeft; Tom H M Ottenhoff; Jacques Neefjes
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.
Nature 2007;450(7170):725-30.
2007: Celia R Berkers; Fijs W B van Leeuwen; Tom A M Groothuis; Victor Peperzak; Erica W van Tilburg; Jannie Borst; Jacques Neefjes; Huib Ovaa
Profiling proteasome activity in tissue with fluorescent probes.
Molecular pharmaceutics 2007;4(5):739-48.
2007: Nobuhito Ono; Ingrid van der Heijden; George L Scheffer; Koen van de Wetering; Elizabeth Van Deemter; Marcel de Haas; Arjan Boerke; Bart M Gadella; Dirk G De Rooij; Jacques Neefjes; Tom A M Groothuis; Lauran Oomen; Lenny Brocks; Toshihisa Ishikawa; Piet Borst
Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm.
The Biochemical journal 2007;406(1):31-40.
2007: Wilbert Zwart; Alexander Griekspoor; Valeria Berno; Kim Lakeman; Kees Jalink; Michael Mancini; Jacques Neefjes; Rob Michalides
PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1.
The EMBO journal 2007;26(15):3534-44.
2007: Andrew D Hislop; Maaike E Ressing; Daphne van Leeuwen; Victoria A Pudney; Daniëlle Horst; Danijela Koppers-Lalic; Nathan P Croft; Jacques Neefjes; Alan B Rickinson; Emmanuel J H J Wiertz
A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates.
The Journal of experimental medicine 2007;204(8):1863-73.
2007: Wilbert Zwart; Alexander Griekspoor; Mariska Rondaij; Desiree Verwoerd; Jacques Neefjes; Rob Michalides
Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.
Molecular cancer therapeutics 2007;6(5):1526-33.
2007: Joost Neijssen; Baoxu Pang; Jacques Neefjes
Gap junction-mediated intercellular communication in the immune system.
Progress in biophysics and molecular biology 2007;94(1-2):207-18.
2007: Anna M Keller; Tom A M Groothuis; Elise A M Veraar; Marije Marsman; Lucas Maillette de Buy Wenniger; Hans Janssen; Jacques Neefjes; Jannie Borst
Costimulatory ligand CD70 is delivered to the immunological synapse by shared intracellular trafficking with MHC class II molecules.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5989-94.
2007: Marie Johansson; Nuno Rocha; Wilbert Zwart; Ingrid Jordens; Lennert Janssen; Coenraad Kuijl; Vesa M Olkkonen; Jacques Neefjes
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin.
The Journal of cell biology 2007;176(4):459-71.
2007: Alexander Griekspoor; Wilbert Zwart; Jacques Neefjes; Rob Michalides
Visualizing the action of steroid hormone receptors in living cells.
Nuclear receptor signaling 2007;5():e003.
2007: Victoria Menéndez-Benito; Jacques Neefjes
Autophagy in MHC class II presentation: sampling from within.
Immunity 2007;26(1):1-3.
2006: Martijn Verdoes; Bogdan I Florea; Victoria Menendez-Benito; Christa Maynard; Martin D Witte; Wouter A van der Linden; Adrianus M C H van den Nieuwendijk; Tanja Hofmann; Celia R Berkers; Fijs W B van Leeuwen; Tom A M Groothuis; Michiel A Leeuwenburgh; Huib Ovaa; Jacques Neefjes; Dmitri V Filippov; Gijsbert A van der Marel; Nico P Dantuma; Herman S Overkleeft
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.
Chemistry & biology 2006;13(11):1217-26.
2006: Tim Elliott; Jacques Neefjes
The complex route to MHC class I-peptide complexes.
Cell 2006;127(2):249-51.
2006: Ingrid Jordens; Wendy Westbroek; Marije Marsman; Nuno Rocha; Mieke Mommaas; Marjan Huizing; Julien Lambert; Jean-Marie Naeyaert; Jacques Neefjes
Rab7 and Rab27a control two motor protein activities involved in melanosomal transport.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2006;19(5):412-23.
2006: Shubing Qian; Eric Reits; Jacques Neefjes; Jeanne M Deslich; Jack R Bennink; jon yewdell
Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):227-33.
2006: Marije Marsman; Ingrid Jordens; Nuno Rocha; Coenraad Kuijl; Lennert Janssen; Jacques Neefjes
A splice variant of RILP induces lysosomal clustering independent of dynein recruitment.
Biochemical and biophysical research communications 2006;344(3):747-56.
2006: Steven Bergink; Florian A Salomons; Deborah Hoogstraten; Tom A M Groothuis; Harm de Waard; Junxin Wu; Li Yuan; Elisabetta Citterio; Adriaan B Houtsmuller; Jacques Neefjes; Jan H J Hoeijmakers; Wim Vermeulen; Nico P Dantuma
DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A.
Genes & development 2006;20(10):1343-52.
2006: Eric Reits; James W Hodge; Carla A Herberts; Tom A M Groothuis; Mala Chakraborty; Elizabeth K Wansley; Kevin A Camphausen; Rosalie M Luiten; Arnoud de Ru; Joost Neijssen; Alexander Griekspoor; Elly Mesman; Frank A W Verreck; Hergen Spits; Jeffrey Schlom; Peter van Veelen; Jacques Neefjes
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy.
The Journal of experimental medicine 2006;203(5):1259-71.
2006: Nico P Dantuma; Tom A M Groothuis; Florian A Salomons; Jacques Neefjes
A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling.
The Journal of cell biology 2006;173(1):19-26.
2006: Carla A Herberts; Joost Neijssen; Jolanda de Haan; Lennert Janssen; Jan Wouter Drijfhout; Eric Reits; Jacques Neefjes
Cutting edge: HLA-B27 acquires many N-terminal dibasic peptides: coupling cytosolic peptide stability to antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2697-701.
2006: Tom A M Groothuis; Nico P Dantuma; Jacques Neefjes; Florian A Salomons
Ubiquitin crosstalk connecting cellular processes.
Cell division 2006;1():21.
2005: Inmaculada Hernández-Muñoz; Panthea Taghavi; Coenraad Kuijl; Jacques Neefjes; Maarten van Lohuizen
Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1.
Molecular and cellular biology 2005;25(24):11047-58.
2005: Ingrid Jordens; Marije Marsman; Coenraad Kuijl; Jacques Neefjes
Rab proteins, connecting transport and vesicle fusion.
Traffic (Copenhagen, Denmark) 2005;6(12):1070-7.
2005: Tom A M Groothuis; Jacques Neefjes
The many roads to cross-presentation.
The Journal of experimental medicine 2005;202(10):1313-8.
2005: Charles F Towne; Ian A York; Joost Neijssen; Margaret L Karow; Andrew J Murphy; David M Valenzuela; George D Yancopoulos; Jacques Neefjes; Kenneth L Rock
Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6605-14.
2005: Tom A M Groothuis; Alexander Griekspoor; Joost Neijssen; Carla A Herberts; Jacques Neefjes
MHC class I alleles and their exploration of the antigen-processing machinery.
Immunological reviews 2005;207():60-76.
2005: Sergio de Almeida; Isabel Fidalgo Carvalho; Carla S Cardoso; João V Cordeiro; Jorge E Azevedo; Jacques Neefjes; Maria de Sousa
HFE cross-talks with the MHC class I antigen presentation pathway.
Blood 2005;106(3):971-7.
2005: Mar Fernandez-Borja; Lennert Janssen; Desiree Verwoerd; Peter L Hordijk; Jacques Neefjes
RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1.
Journal of cell science 2005;118(Pt 12):2661-70.
2005: Hedwich F Kuipers; Paula J Biesta; Tom A M Groothuis; Jacques Neefjes; A Mieke Mommaas; Peter J van den Elsen
Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing microdomains.
Human immunology 2005;66(6):653-65.
2005: Alexander Griekspoor; Wilbert Zwart; Jacques Neefjes
Presenting antigen presentation in living cells using biophysical techniques.
Current opinion in microbiology 2005;8(3):338-43.
2005: Danijela Koppers-Lalic; Eric Reits; Maaike E Ressing; Andrea Lipinska; Rupert Abele; Joachim Koch; Marisa Marcondes Rezende; Pieter Admiraal; Daphne van Leeuwen; Krystyna Bienkowska-Szewczyk; Thomas C Mettenleiter; F A M Rijsewijk; Robert Tampé; Jacques Neefjes; Emmanuel J H J Wiertz
Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5144-9.
2005: Joost Neijssen; Carla A Herberts; Jan Wouter Drijfhout; Eric Reits; Lennert Janssen; Jacques Neefjes
Cross-presentation by intercellular peptide transfer through gap junctions.
Nature 2005;434(7029):83-8.
2005: Wilbert Zwart; Alexander Griekspoor; Coenraad Kuijl; Marije Marsman; Jacco van Rheenen; Hans Janssen; Jero Calafat; Marieke van Ham; Lennert Janssen; Marcel van Lith; Kees Jalink; Jacques Neefjes
Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape.
Immunity 2005;22(2):221-33.
2005: Clifford V Harding; Jacques Neefjes
Antigen processing and recognition.
Current opinion in immunology 2005;17(1):55-7.
2005: Tom A M Groothuis; Jacques Neefjes
The ins and outs of intracellular peptides and antigen presentation by MHC class I molecules.
Current topics in microbiology and immunology 2005;300():127-48.
2005: Marije Marsman; Ingrid Jordens; Alexander Griekspoor; Jacques Neefjes
Chaperoning antigen presentation by MHC class II molecules and their role in oncogenesis.
Advances in cancer research 2005;93():129-58.
2004: Rob Michalides; Alexander Griekspoor; Astrid Balkenende; Desiree Verwoerd; Lennert Janssen; Kees Jalink; Arno N Floore; Arno Velds; Laura J van't Veer; Jacques Neefjes
Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer.
Cancer cell 2004;5(6):597-605.
2004: Marije Marsman; Ingrid Jordens; Coenraad Kuijl; Lennert Janssen; Jacques Neefjes
Dynein-mediated vesicle transport controls intracellular Salmonella replication.
Molecular biology of the cell 2004;15(6):2954-64.
2004: Eric Reits; Joost Neijssen; Carla A Herberts; Willemien Benckhuijsen; Lennert Janssen; Jan Wouter Drijfhout; Jacques Neefjes
A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation.
Immunity 2004;20(4):495-506.
2004: Jacques Neefjes; Nico P Dantuma
Fluorescent probes for proteolysis: tools for drug discovery.
Nature reviews. Drug discovery 2004;3(1):58-69.
2003: jon yewdell; Eric Reits; Jacques Neefjes
Making sense of mass destruction: quantitating MHC class I antigen presentation.
Nature reviews. Immunology 2003;3(12):952-61.
2003: Danijela Koppers-Lalic; Michal Rychlowski; Daphne van Leeuwen; F A M Rijsewijk; Maaike E Ressing; Jacques Neefjes; Krystyna Bienkowska-Szewczyk; Emmanuel J H J Wiertz
Bovine herpesvirus 1 interferes with TAP-dependent peptide transport and intracellular trafficking of MHC class I molecules in human cells.
Archives of virology 2003;148(10):2023-37.
2003: Maaike E Ressing; Daphne van Leeuwen; Frank A W Verreck; Raquel Gomez; Bianca Heemskerk; Mireille Toebes; Maureen M Mullen; Theodore S Jardetzky; Richard Longnecker; Marco W Schilham; Tom H M Ottenhoff; Jacques Neefjes; Schumacher Ton; Lindsey M Hutt-Fletcher; Emmanuel J H J Wiertz
Interference with T cell receptor-HLA-DR interactions by Epstein-Barr virus gp42 results in reduced T helper cell recognition.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11583-8.
2003: Marcel van Lith; Marieke van Ham; Jacques Neefjes
Stable expression of MHC class I heavy chain/HLA-DO complexes at the plasma membrane.
European journal of immunology 2003;33(5):1145-51.
2003: Carla A Herberts; Eric Reits; Jacques Neefjes
Proteases, proteases and proteases for presentation.
Nature immunology 2003;4(4):306-8.
2003: Eric Reits; Alexander Griekspoor; Joost Neijssen; Tom A M Groothuis; Kees Jalink; Peter van Veelen; Hans Janssen; Jero Calafat; Jan Wouter Drijfhout; Jacques Neefjes
Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.
Immunity 2003;18(1):97-108.
2002: Marcel van Lith; Marieke van Ham; Jacques Neefjes
Novel polymorphisms in HLA-DOA and HLA-DOB in B-cell malignancies.
Immunogenetics 2002;54(8):591-5.
2002: Monique Grommé; Jacques Neefjes
Antigen degradation or presentation by MHC class I molecules via classical and non-classical pathways.
Molecular immunology 2002;39(3-4):181-202.
2002: Martin Villalba; Kun Bi; Junru Hu; Yoav Altman; Paul J Bushway; Eric Reits; Jacques Neefjes; Gottfried Baier; Robert T Abraham; Amnon Altman
Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.
The Journal of cell biology 2002;157(2):253-63.
2002: Eric Reits; Alexander Griekspoor; Jacques Neefjes
Herpes viral proteins manipulating the peptide transporter TAP.
Current topics in microbiology and immunology 2002;269():75-83.
2001: C Roucard; C Thomas; Marie-Anne Pasquier; J Trowsdale; Jean-Jacques Sotto; Jacques Neefjes; Marieke van Ham
In vivo and in vitro modulation of HLA-DM and HLA-DO is induced by B lymphocyte activation.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(12):6849-58.
2001: Ingrid Jordens; Mar Fernandez-Borja; Marije Marsman; S Dusseljee; Lennert Janssen; Jero Calafat; Hans Janssen; R Wubbolts; Jacques Neefjes
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors.
Current biology : CB 2001;11(21):1680-5.
2001: Danijela Koppers-Lalic; F A M Rijsewijk; SB Verschuren; Jacqueline A M van Gaans-van den Brink; A Neisig; Maaike E Ressing; Jacques Neefjes; Emmanuel J H J Wiertz
The UL41-encoded virion host shutoff (vhs) protein and vhs-independent mechanisms are responsible for down-regulation of MHC class I molecules by bovine herpesvirus 1.
The Journal of general virology 2001;82(Pt 9):2071-81.
2001: C Knuehl; Pieter Spee; Thomas Ruppert; Ulrike Kuckelkorn; Peter Henklein; Jacques Neefjes; Peter-M Kloetzel
The murine cytomegalovirus pp89 immunodominant H-2Ld epitope is generated and translocated into the endoplasmic reticulum as an 11-mer precursor peptide.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1515-21.
2001: Marcel van Lith; Marieke van Ham; Alexander Griekspoor; EP Tjin; Desiree Verwoerd; Jero Calafat; Hans Janssen; Eric Reits; L Pastoors; Jacques Neefjes
Regulation of MHC class II antigen presentation by sorting of recycling HLA-DM/DO and class II within the multivesicular body.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(2):884-92.
2001: Hubert P J C de Leeuw; Mar Fernandez-Borja; Eric Reits; Thalia Romani de Wit; P M Wijers-Koster; Peter L Hordijk; Jacques Neefjes; Jan A van Mourik; Jan Voorberg
Small GTP-binding protein Ral modulates regulated exocytosis of von Willebrand factor by endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(6):899-904.
2001: Eric Reits; Jacques Neefjes
From fixed to FRAP: measuring protein mobility and activity in living cells.
Nature cell biology 2001;3(6):E145-7.
2001: A Neisig; Jacques Neefjes
Application of one-dimensional isoelectric focusing to separate different major histocompatibility complex class I alleles and determine their allelic interactions with transporter associated with antigen processing (TAP).
Methods in molecular biology (Clifton, N.J.) 2001;156():153-63.
2000: Eric Reits; Alexander Griekspoor; Jacques Neefjes
How does TAP pump peptides? insights from DNA repair and traffic ATPases.
Immunology today 2000;21(12):598-600.
2000: Marieke van Ham; Marcel van Lith; Alexander Griekspoor; Jacques Neefjes
What to do with HLA-DO?
Immunogenetics 2000;51(10):765-70.
2000: Jens Koopm,ann; J Albring; E Hüter; N Bulbuc; Pieter Spee; Jacques Neefjes; Günter J Hämmerling; Frank Momburg
Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel.
Immunity 2000;13(1):117-27.
2000: Harpreet Singh-Jasuja; René E M Toes; Pieter Spee; Christian Münz; Norbert Hilf; Stephen P Schoenberger; P Ricciardi-Castagnoli; Jacques Neefjes; Hans-Georg Rammensee; Danièle Arnold-Schild; Hansjörg Schild
Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis.
The Journal of experimental medicine 2000;191(11):1965-74.
2000: Eric Reits; JC Vos; Monique Grommé; Jacques Neefjes
The major substrates for TAP in vivo are derived from newly synthesized proteins.
Nature 2000;404(6779):774-8.
2000: Marieke van Ham; Marcel van Lith; B Lillemeier; EP Tjin; U Grüneberg; Dinah Rahman; L Pastoors; Krista E van Meijgaarden; C Roucard; J Trowsdale; Tom H M Ottenhoff; Darryl Pappin; Jacques Neefjes
Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO.
The Journal of experimental medicine 2000;191(7):1127-36.
2000: Nico J Beekman; Peter van Veelen; Thorbald van Hall; A Neisig; Alice J A M Sijts; Marcel Camps; Peter-M Kloetzel; Jacques Neefjes; Cornelis J M Melief; Ferry Ossendorp
Abrogation of CTL epitope processing by single amino acid substitution flanking the C-terminal proteasome cleavage site.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1898-905.
2000: JC Vos; Eric Reits; E Wojcik-Jacobs; Jacques Neefjes
Head-head/tail-tail relative orientation of the pore-forming domains of the heterodimeric ABC transporter TAP.
Current biology : CB 2000;10(1):1-7.
1999: JC Vos; Pieter Spee; Frank Momburg; Jacques Neefjes
Membrane topology and dimerization of the two subunits of the transporter associated with antigen processing reveal a three-domain structure.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6679-85.
1999: R Wubbolts; Jacques Neefjes
Intracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors.
Immunological reviews 1999;172():189-208.
1999: Mads Hald Andersen; J E Bonfill; A Neisig; Gemma Arsequell; Ib Søndergaard; Gregorio Valencia; Jacques Neefjes; Jesper Zeuthen; Tim Elliott; JS Haurum
Phosphorylated peptides can be transported by TAP molecules, presented by class I MHC molecules, and recognized by phosphopeptide-specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3812-8.
1999: Monique Grommé; F G Uytdehaag; Hans Janssen; Jero Calafat; RS van Binnendijk; M J Kenter; A Tulp; Desiree Verwoerd; Jacques Neefjes
Recycling MHC class I molecules and endosomal peptide loading.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(18):10326-31.
1999: Pieter Spee; J Subjeck; Jacques Neefjes
Identification of novel peptide binding proteins in the endoplasmic reticulum: ERp72, calnexin, and grp170.
Biochemistry 1999;38(32):10559-66.
1999: JS Haurum; I B Høier; Gemma Arsequell; A Neisig; Gregorio Valencia; Jesper Zeuthen; Jacques Neefjes; Tim Elliott
Presentation of cytosolic glycosylated peptides by human class I major histocompatibility complex molecules in vivo.
The Journal of experimental medicine 1999;190(1):145-50.
1999: Jacques Neefjes
CIIV, MIIC and other compartments for MHC class II loading.
European journal of immunology 1999;29(5):1421-5.
1999: A Tulp; Desiree Verwoerd; Jacques Neefjes
Lectin-induced retardation of subcellular organelles during preparative density gradient electrophoresis: selective purification of plasma membranes.
Electrophoresis 1999;20(3):438-44.
1999: R Wubbolts; Mar Fernandez-Borja; Ingrid Jordens; Eric Reits; S Dusseljee; CJ Echeverri; R B Vallee; Jacques Neefjes
Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments.
Journal of cell science 1999;112 ( Pt 6)():785-95.
1999: A Tulp; Desiree Verwoerd; Jacques Neefjes
Electromigration for separations of protein complexes.
Journal of chromatography. B, Biomedical sciences and applications 1999;722(1-2):141-51.
1999: Mar Fernandez-Borja; R Wubbolts; Jero Calafat; Hans Janssen; Nullin Divecha; S Dusseljee; Jacques Neefjes
Multivesicular body morphogenesis requires phosphatidyl-inositol 3-kinase activity.
Current biology : CB 1999;9(1):55-8.
1998: S Dusseljee; R Wubbolts; Desiree Verwoerd; A Tulp; Hans Janssen; Jero Calafat; Jacques Neefjes
Removal and degradation of the free MHC class II beta chain in the endoplasmic reticulum requires proteasomes and is accelerated by BFA.
Journal of cell science 1998;111 ( Pt 15)():2217-26.
1998: AM Benham; Monique Grommé; Jacques Neefjes
Allelic differences in the relationship between proteasome activity and MHC class I peptide loading.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):83-9.
1998: A Tulp; Mar Fernandez-Borja; Desiree Verwoerd; Jacques Neefjes
High-resolution density gradient electrophoresis of subcellular organelles and proteins under nondenaturing conditions.
Electrophoresis 1998;19(8-9):1288-93.
1998: A Tulp; Desiree Verwoerd; AM Benham; Kees Jalink; C Sier; Jacques Neefjes
High performance density gradient electrophoresis of subcellular organelles, protein complexes and proteins.
Electrophoresis 1998;19(7):1171-8.
1998: A Neisig; Cornelis J M Melief; Jacques Neefjes
Reduced cell surface expression of HLA-C molecules correlates with restricted peptide binding and stable TAP interaction.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):171-9.
1997: AM Benham; Jacques Neefjes
Proteasome activity limits the assembly of MHC class I molecules after IFN-gamma stimulation.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):5896-904.
1997: A Tulp; Desiree Verwoerd; AM Benham; Jacques Neefjes
High-resolution density gradient electrophoresis of proteins and subcellular organelles.
Electrophoresis 1997;18(14):2509-15.
1997: SM van Ham; EP Tjin; B F Lillemeier; U Grüneberg; Krista E van Meijgaarden; L Pastoors; Desiree Verwoerd; A Tulp; Benito Canas; Dinah Rahman; Tom H M Ottenhoff; Darryl Pappin; J Trowsdale; Jacques Neefjes
HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading.
Current biology : CB 1997;7(12):950-7.
1997: Eric Reits; AM Benham; B Plougastel; Jacques Neefjes; J Trowsdale
Dynamics of proteasome distribution in living cells.
The EMBO journal 1997;16(20):6087-94.
1997: Pieter Spee; Jacques Neefjes
TAP-translocated peptides specifically bind proteins in the endoplasmic reticulum, including gp96, protein disulfide isomerase and calreticulin.
European journal of immunology 1997;27(9):2441-9.
1997: MC Tan; A Mieke Mommaas; Jan Wouter Drijfhout; R Jordens; Jos J M Onderwater; Desiree Verwoerd; Aat A Mulder; A N van der Heiden; D Scheidegger; Lauran Oomen; Tom H M Ottenhoff; A Tulp; Jacques Neefjes; Frits Koning
Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells.
European journal of immunology 1997;27(9):2426-35.
1997: Monique Grommé; R van der Valk; K Sliedregt; L Vernie; R Liskamp; Günter J Hämmerling; Jens Koopm,ann; Frank Momburg; Jacques Neefjes
The rational design of TAP inhibitors using peptide substrate modifications and peptidomimetics.
European journal of immunology 1997;27(4):898-904.
1997: MC Tan; A Mieke Mommaas; Jan Wouter Drijfhout; R Jordens; Jos J M Onderwater; Desiree Verwoerd; Aat A Mulder; A N van der Heiden; Tom H M Ottenhoff; M Cella; A Tulp; Jacques Neefjes; Frits Koning
Mannose receptor mediated uptake of antigens strongly enhances HLA-class II restricted antigen presentation by cultured dendritic cells.
Advances in experimental medicine and biology 1997;417():171-4.
1997: Vincenzo Cerundolo; AM Benham; Veronique M Braud; S Mukherjee; K Gould; B Macino; Jacques Neefjes; A Townsend
The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells.
European journal of immunology 1997;27(1):336-41.
1996: Mar Fernandez-Borja; Jacques Neefjes
How cells instruct the immune system to carry out their elimination.
Biochemical Society transactions 1996;24(4):1039-43.
1996: R Wubbolts; Mar Fernandez-Borja; Lauran Oomen; Desiree Verwoerd; Hans Janssen; Jero Calafat; A Tulp; S Dusseljee; Jacques Neefjes
Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface.
The Journal of cell biology 1996;135(3):611-22.
1996: Gaby Brouns; Evert de Vries; Jacques Neefjes; Jannie Borst
Assembled pre-B cell receptor complexes are retained in the endoplasmic reticulum by a mechanism that is not selective for the pseudo-light chain.
The Journal of biological chemistry 1996;271(32):19272-8.
1996: Ferry Ossendorp; M Eggers; A Neisig; T Ruppert; Marcus Groettrup; A Sijts; E Mengedë; P M Kloetzel; Jacques Neefjes; Ulrich H Koszinowski; Cornelis J M Melief
A single residue exchange within a viral CTL epitope alters proteasome-mediated degradation resulting in lack of antigen presentation.
Immunity 1996;5(2):115-24.
1996: Jens Koopm,ann; M Post; Jacques Neefjes; Günter J Hämmerling; Frank Momburg
Translocation of long peptides by transporters associated with antigen processing (TAP).
European journal of immunology 1996;26(8):1720-8.
1996: J W Lewis; A Neisig; Jacques Neefjes; Tim Elliott
Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP.
Current biology : CB 1996;6(7):873-83.
1996: Mar Fernandez-Borja; Desiree Verwoerd; F Sanderson; johannes aerts; J Trowsdale; A Tulp; Jacques Neefjes
HLA-DM and MHC class II molecules co-distribute with peptidase-containing lysosomal subcompartments.
International immunology 1996;8(5):625-40.
1996: A Neisig; R Wubbolts; X Zang; Cornelis J M Melief; Jacques Neefjes
Allele-specific differences in the interaction of MHC class I molecules with transporters associated with antigen processing.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(9):3196-206.
1996: A J Sijts; A Neisig; Jacques Neefjes; Eric G Pamer
Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):683-92.
1996: A Tulp; Desiree Verwoerd; Mar Fernandez-Borja; Jacques Neefjes; A A Hart
High resolution density gradient electrophoresis of cellular organelles.
Electrophoresis 1996;17(1):173-8.
1996: F Sanderson; C Thomas; Jacques Neefjes; J Trowsdale
Association between HLA-DM and HLA-DR in vivo.
Immunity 1996;4(1):87-96.
1995: AM Benham; Jacques Neefjes
Antigen processing by the class I pathway.
Biochemical Society transactions 1995;23(3):664-9.
1995: Peter J Peters; G Raposo; Jacques Neefjes; Viola Oorschot; Richtje Leijendekker; Hans J Geuze; H L Ploegh
Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes.
The Journal of experimental medicine 1995;182(2):325-34.
1995: AM Benham; A Tulp; Jacques Neefjes
Synthesis and assembly of MHC-peptide complexes.
Immunology today 1995;16(7):359-62.
1995: Monique J Kleijmeer; M A Ossevoort; C J van Veen; Jaap J van Hellemond; Jacques Neefjes; W Martin Kast; Cornelis J M Melief; Hans J Geuze
MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5715-24.
1995: Jacques Neefjes; E Gottfried; J Roelse; Monique Grommé; R Obst; Günter J Hämmerling; Frank Momburg
Analysis of the fine specificity of rat, mouse and human TAP peptide transporters.
European journal of immunology 1995;25(4):1133-6.
1995: A Neisig; J Roelse; A J Sijts; Ferry Ossendorp; M C Feltkamp; W Martin Kast; Cornelis J M Melief; Jacques Neefjes
Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(3):1273-9.
1994: F Sanderson; Monique J Kleijmeer; A Kelly; Desiree Verwoerd; A Tulp; Jacques Neefjes; Hans J Geuze; J Trowsdale
Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments.
Science (New York, N.Y.) 1994;266(5190):1566-9.
1994: J Roelse; Monique Grommé; Frank Momburg; Günter J Hämmerling; Jacques Neefjes
Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling.
The Journal of experimental medicine 1994;180(5):1591-7.
1994: Jero Calafat; M Nijenhuis; Hans Janssen; A Tulp; S Dusseljee; R Wubbolts; Jacques Neefjes
Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures.
The Journal of cell biology 1994;126(4):967-77.
1994: Frank Momburg; J Roelse; Jacques Neefjes; Günter J Hämmerling
Peptide transporters and antigen processing.
Behring Institute Mitteilungen 1994;(94):26-36.
1994: Frank Momburg; J Roelse; Günter J Hämmerling; Jacques Neefjes
Peptide size selection by the major histocompatibility complex-encoded peptide transporter.
The Journal of experimental medicine 1994;179(5):1613-23.
1994: M Nijenhuis; Jero Calafat; K C Kuijpers; Hans Janssen; M de Haas; Tommy W Nordeng; Oddmund Bakke; Jacques Neefjes
Targeting major histocompatibility complex class II molecules to the cell surface by invariant chain allows antigen presentation upon recycling.
European journal of immunology 1994;24(4):873-83.
1994: Frank Momburg; J Roelse; J C Howard; G W Butcher; Günter J Hämmerling; Jacques Neefjes
Selectivity of MHC-encoded peptide transporters from human, mouse and rat.
Nature 1994;367(6464):648-51.
1994: Frank Momburg; Jacques Neefjes; Günter J Hämmerling
Peptide selection by MHC-encoded TAP transporters.
Current opinion in immunology 1994;6(1):32-7.
1994: M Nijenhuis; Jacques Neefjes
Early events in the assembly of major histocompatibility complex class II heterotrimers from their free subunits.
European journal of immunology 1994;24(1):247-56.
1993: Jacques Neefjes; Günter J Hämmerling; Frank Momburg
Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide.
The Journal of experimental medicine 1993;178(6):1971-80.
1993: Jacques Neefjes; F Momburg; Günter J Hämmerling
Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter.
Science (New York, N.Y.) 1993;261(5122):769-71.
1993: M J Bijlmakers; Jacques Neefjes; E H Wojcik-Jacobs; Hidde L Ploegh
The assembly of H2-Kb class I molecules translated in vitro requires oxidized glutathione and peptide.
European journal of immunology 1993;23(6):1305-13.
1993: Jacques Neefjes; J Dierx; Hidde L Ploegh
The effect of anchor residue modifications on the stability of major histocompatibility complex class I-peptide interactions.
European journal of immunology 1993;23(4):840-5.
1993: Jacques Neefjes; Frank Momburg
Cell biology of antigen presentation.
Current opinion in immunology 1993;5(1):27-34.
1992: Frank Momburg; V Ortiz-Navarrete; Jacques Neefjes; E Goulmy; Y van de Wal; H Spits; S J Powis; G W Butcher; J C Howard; Peter Walden
Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation.
Nature 1992;360(6400):174-7.
1992: K C Kuijpers; F J van Kemenade; Berend Hooibrink; Jacques Neefjes; C J Lucas; René A W van Lier; Frank Miedema
HLA class I and II molecules present influenza virus antigens with different kinetics.
European journal of immunology 1992;22(9):2339-45.
1992: Jacques Neefjes; L Smit; M Gehrmann; Hidde L Ploegh
The fate of the three subunits of major histocompatibility complex class I molecules.
European journal of immunology 1992;22(6):1609-14.
1992: Jacques Neefjes; Hidde L Ploegh
Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes.
The EMBO journal 1992;11(2):411-6.
1991: Jacques Neefjes; Schumacher Ton; Hidde L Ploegh
Assembly and intracellular transport of major histocompatibility complex molecules.
Current opinion in cell biology 1991;3(4):601-9.
1991: Schumacher Ton; ML De Bruijn; L N Vernie; W Martin Kast; Cornelis J M Melief; Jacques Neefjes; Hidde L Ploegh
Peptide selection by MHC class I molecules.
Nature 1991;350(6320):703-6.
1991: Peter J Peters; Jacques Neefjes; Viola Oorschot; H L Ploegh; Hans J Geuze
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments.
Nature 1991;349(6311):669-76.
1990: Hidde L Ploegh; Jacques Neefjes
Protein glycosylation.
Current opinion in cell biology 1990;2(6):1125-30.
1990: Jacques Neefjes; T Hengeveld; O Tol; Hidde L Ploegh
Intracellular interactions of transferrin and its receptor during biosynthesis.
The Journal of cell biology 1990;111(4):1383-92.
1990: Schumacher Ton; M T Heemels; Jacques Neefjes; W Martin Kast; Cornelis J M Melief; Hidde L Ploegh
Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.
Cell 1990;62(3):563-7.
1990: Hans-Gustaf Ljunggren; N J Stam; C Ohlén; Jacques Neefjes; Petter Höglund; M T Heemels; J Bastin; Schumacher Ton; A Townsend; Klas Kärre
Empty MHC class I molecules come out in the cold.
Nature 1990;346(6283):476-80.
1990: Jacques Neefjes; V Stollorz; Peter J Peters; H J Geuze; Hidde L Ploegh
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route.
Cell 1990;61(1):171-83.
1990: Jacques Neefjes; ML De Bruijn; C J Boog; JD Nieland; J Boes; Cornelis J M Melief; Hidde L Ploegh
N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response.
The Journal of experimental medicine 1990;171(2):583-8.
1989: F T Rotteveel; Jacques Neefjes; H L Ploegh; C J Lucas
Influenza virus changes cell-surface glycoproteins including major histocompatibility complex determinants on lymphocytes.
Human immunology 1989;26(3):199-213.
1989: Jacques Neefjes; J Lindhout; H J Broxterman; G A van der Marel; J H van Boom; Hidde L Ploegh
Non-carrier-mediated uptake of the mannosidase I inhibitor 1-deoxymannojirimycin by K562 erythroleukemic cells.
The Journal of biological chemistry 1989;264(17):10271-5.
1989: Maria Masucci; N J Stam; S Torsteinsdottir; Jacques Neefjes; George Klein; H L Ploegh
Allele-specific down-regulation of MHC class I antigens in Burkitt lymphoma lines.
Cellular immunology 1989;120(2):396-400.
1989: C J Boog; Jacques Neefjes; J Boes; Hidde L Ploegh; Cornelis J M Melief
Specific immune responses restored by alteration in carbohydrate chains of surface molecules on antigen-presenting cells.
European journal of immunology 1989;19(3):537-42.
1989: Ilias Doxiadis; K Krumbacher; Jacques Neefjes; H L Ploegh; Hans Grosse-Wilde
Biochemical evidence that the DLA-B locus codes for a class II determinant expressed on all canine peripheral blood lymphocytes.
Experimental and clinical immunogenetics 1989;6(3):219-24.
1988: J G Bolscher; M M van der Bijl; Jacques Neefjes; A Hall; Lou A Smets; Hidde L Ploegh
Ras (proto)oncogene induces N-linked carbohydrate modification: temporal relationship with induction of invasive potential.
The EMBO journal 1988;7(11):3361-8.
1988: Jacques Neefjes; J M Verkerk; H J Broxterman; G A van der Marel; J H van Boom; Hidde L Ploegh
Recycling glycoproteins do not return to the cis-Golgi.
The Journal of cell biology 1988;107(1):79-87.
1988: Jacques Neefjes; Hidde L Ploegh
Allele and locus-specific differences in cell surface expression and the association of HLA class I heavy chain with beta 2-microglobulin: differential effects of inhibition of glycosylation on class I subunit association.
European journal of immunology 1988;18(5):801-10.
1988: L M Dobbe; N J Stam; Jacques Neefjes; Marius J Giphart
Biochemical complexity of serum HLA class I molecules.
Immunogenetics 1988;27(3):203-10.
1987: Rob A Gruters; Jacques Neefjes; M Tersmette; R E de Goede; A Tulp; H G Huisman; Frank Miedema; Hidde L Ploegh
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase.
Nature 1987;330(6143):74-7.
1987: R S Rein; G H Seemann; Jacques Neefjes; F M Hochstenbach; N J Stam; H L Ploegh
Association with beta 2-microglobulin controls the expression of transfected human class I genes.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(4):1178-83.
1986: Jacques Neefjes; Ilias Doxiadis; N J Stam; C J Beckers; H L Ploegh
An analysis of class I antigens of man and other species by one-dimensional IEF and immunoblotting.
Immunogenetics 1986;23(3):164-71.