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Stevens Negus

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TOP 3
Matthew L Banks; Bruce E Blough; Timothy R Fennell; Rodney W Snyder; S Stevens Negus
Role of phenmetrazine as an active metabolite of phendimetrazine: Evidence from studies of drug discrimination and pharmacokinetics in rhesus monkeys.
Marisa B Rosenberg; F Ivy Carroll; S Stevens Negus
Effects of monoamine reuptake inhibitors in assays of acute pain-stimulated and pain-depressed behavior in rats.
Morgane Thomsen; S Stevens Negus; Andrew C Barrett; S Barak Caine
Cocaine versus food choice procedure in rats: environmental manipulations and effects of amphetamine.

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2013: Matthew L Banks; Bruce E Blough; Timothy R Fennell; Rodney W Snyder; S Stevens Negus
Role of phenmetrazine as an active metabolite of phendimetrazine: Evidence from studies of drug discrimination and pharmacokinetics in rhesus monkeys.
Drug and alcohol dependence 2013;130(1-3):158-66.
2013: Marisa B Rosenberg; F Ivy Carroll; S Stevens Negus
Effects of monoamine reuptake inhibitors in assays of acute pain-stimulated and pain-depressed behavior in rats.
The journal of pain : official journal of the American Pain Society 2013;14(3):246-59.
2013: Morgane Thomsen; S Stevens Negus; Andrew C Barrett; S Barak Caine
Cocaine versus food choice procedure in rats: environmental manipulations and effects of amphetamine.
Journal of the experimental analysis of behavior 2013;99(2):211-33.
2013: S Stevens Negus; Matthew L Banks
Medications development for opioid abuse.
Cold Spring Harbor perspectives in medicine 2013;3(1):a012104.
2012: Andrew J Kwilasz; S Stevens Negus
Dissociable effects of the cannabinoid receptor agonists Δ9-tetrahydrocannabinol and CP55940 on pain-stimulated versus pain-depressed behavior in rats.
The Journal of pharmacology and experimental therapeutics 2012;343(2):389-400.
2012: S Stevens Negus; Robert H O'Connell; Ahmad A Altarifi; John E Folk; Marisa B Rosenberg; Kenner C Rice
Effects of the δ opioid receptor agonist SNC80 on pain-related depression of intracranial self-stimulation (ICSS) in rats.
The journal of pain : official journal of the American Pain Society 2012;13(4):317-27.
2012: S Stevens Negus; Robert O'Connell; Kejun Cheng; Ember Morrissey; Kenner C Rice
Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats.
The Journal of pharmacology and experimental therapeutics 2012;340(3):501-9.
2012: Matthew L Banks; S Stevens Negus
Preclinical Determinants of Drug Choice under Concurrent Schedules of Drug Self-Administration.
Advances in pharmacological sciences 2012;2012():281768.
2012: S Stevens Negus; John E Folk; Ember M Morrissey; Kenner C Rice
Interaction between Mu and Delta Opioid Receptor Agonists in an Assay of Capsaicin-Induced Thermal Allodynia in Rhesus Monkeys.
Pain research and treatment 2012;2012():867067.
2011: Matthew L Banks; Bruce E Blough; S Stevens Negus
Effects of monoamine releasers with varying selectivity for releasing dopamine/norepinephrine versus serotonin on choice between cocaine and food in rhesus monkeys.
Behavioural pharmacology 2011;22(8):824-36.
2011: Matthew L Banks; John E Folk; Kenner C Rice; Peter G Roma; S Stevens Negus
Effects of the delta-opioid agonist SNC80 on the abuse liability of methadone in rhesus monkeys: a behavioral economic analysis.
Psychopharmacology 2011;216(3):431-9.
2010: Matthew L Banks; John E Folk; Kenner C Rice; S Stevens Negus
Selective enhancement of fentanyl-induced antinociception by the delta agonist SNC162 but not by ketamine in rhesus monkeys: Further evidence supportive of delta agonists as candidate adjuncts to mu opioid analgesics.
Pharmacology, biochemistry, and behavior 2010;97(2):205-12.
2010: Matthew L Banks; Kenner C Rice; S Stevens Negus
Antinociceptive interactions between Mu-opioid receptor agonists and the serotonin uptake inhibitor clomipramine in rhesus monkeys: role of Mu agonist efficacy.
The Journal of pharmacology and experimental therapeutics 2010;335(2):497-505.
2010: Jennifer L Newman; S Stevens Negus; Anthony Lozama; Thomas E Prisinzano; Nancy K Mello
Behavioral evaluation of modafinil and the abuse-related effects of cocaine in rhesus monkeys.
Experimental and clinical psychopharmacology 2010;18(5):395-408.
2010: K J Jackson; Frank Ivy Carroll; S Stevens Negus; M Imad Damaj
Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse.
Psychopharmacology 2010;210(2):285-94.
2010: S Stevens Negus; Ember M Morrissey; Marisa Rosenberg; K Cheng; Kenner C Rice
Effects of kappa opioids in an assay of pain-depressed intracranial self-stimulation in rats.
Psychopharmacology 2010;210(2):149-59.
2010: S Stevens Negus; M L Banks; J E Folk; Kenner C Rice
Modulation of delta opioid agonist-induced antinociception by repeated morphine pretreatment in rhesus monkeys.
Life sciences 2010;86(11-12):385-92.
2010: S Stevens Negus; Edward J Bilsky; Gail Pereira Do Carmo; Glenn W Stevenson
Rationale and methods for assessment of pain-depressed behavior in preclinical assays of pain and analgesia.
Methods in molecular biology (Clifton, N.J.) 2010;617():79-91.
2010: Matthew L Banks; S Stevens Negus
Effects of extended cocaine access and cocaine withdrawal on choice between cocaine and food in rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(2):493-504.
2009: Heather L Kimmel; Daniel F Manvich; Bruce E Blough; S Stevens Negus; Leonard L Howell
Behavioral and neurochemical effects of amphetamine analogs that release monoamines in the squirrel monkey.
Pharmacology, biochemistry, and behavior 2009;94(2):278-84.
2009: Glenn W Stevenson; Jim Cormier; Hannah Mercer; Chloe Adams; Catherine Dunbar; S Stevens Negus; Edward J Bilsky
Targeting pain-depressed behaviors in preclinical assays of pain and analgesia: drug effects on acetic acid-depressed locomotor activity in ICR mice.
Life sciences 2009;85(7-8):309-15.
2009: Gail Pereira Do Carmo; Glenn W Stevenson; William A Carlezon; S Stevens Negus
Effects of pain- and analgesia-related manipulations on intracranial self-stimulation in rats: further studies on pain-depressed behavior.
Pain 2009;144(1-2):170-7.
2009: S Stevens Negus; M H Baumann; R B Rothman; N K Mello; Bruce E Blough
Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.
The Journal of pharmacology and experimental therapeutics 2009;329(1):272-81.
2009: S Stevens Negus; Kenner C Rice
Mechanisms of withdrawal-associated increases in heroin self-administration: pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(4):899-911.
2009: Gail Pereira Do Carmo; John E Folk; Kenner C Rice; Elena Chartoff; William A Carlezon; S Stevens Negus
The selective non-peptidic delta opioid agonist SNC80 does not facilitate intracranial self-stimulation in rats.
European journal of pharmacology 2009;604(1-3):58-65.
2008: S Stevens Negus; Katrina Schrode; Glenn W Stevenson
Micro/kappa opioid interactions in rhesus monkeys: implications for analgesia and abuse liability.
Experimental and clinical psychopharmacology 2008;16(5):386-99.
2008: Jennifer L Mathews; Brian S Fulton; S Stevens Negus; John L Neumeyer; Jean M Bidlack
In vivo characterization of (-)(-)MCL-144 and (+)(-)MCL-193: isomeric, bivalent ligands with mu/kappa agonist properties.
Neurochemical research 2008;33(10):2142-50.
2008: Gail Pereira Do Carmo; Robin Polt; Edward J Bilsky; Kenner C Rice; S Stevens Negus
Behavioral pharmacology of the mu/delta opioid glycopeptide MMP2200 in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2008;326(3):939-48.
2008: Heather L Kimmel; S Stevens Negus; Kristin M Wilcox; Sarah B Ewing; Jeffrey Stehouwer; Mark M Goodman; John R Votaw; Nancy K Mello; Frank carroll; Leonard L Howell
Relationship between rate of drug uptake in brain and behavioral pharmacology of monoamine transporter inhibitors in rhesus monkeys.
Pharmacology, biochemistry, and behavior 2008;90(3):453-62.
2008: Nancy K Mello; S Stevens Negus; Inge M Knudson; Maureen Kelly; Jack H Mendelson
Effects of estradiol on cocaine self-administration and cocaine discrimination by female rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(4):783-95.
2007: Charles W Schindler; Zofi Graczyk; Joanne P Gilman; S Stevens Negus; Jack Bergman; Nancy K Mello; Steven R Goldberg
Effects of kappa opioid agonists alone and in combination with cocaine on heart rate and blood pressure in conscious squirrel monkeys.
European journal of pharmacology 2007;576(1-3):107-13.
2007: Nancy K Mello; S Stevens Negus
Effects of d-amphetamine and buprenorphine combinations on speedball (cocaine+heroin) self-administration by rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(9):1985-94.
2007: S Stevens Negus; Nancy K Mello; Bruce E Blough; Michael H Baumann; Richard B Rothman
Monoamine releasers with varying selectivity for dopamine/norepinephrine versus serotonin release as candidate "agonist" medications for cocaine dependence: studies in assays of cocaine discrimination and cocaine self-administration in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2007;320(2):627-36.
2007: Gerald Zernig; Serge H Ahmed; Rudolf N Cardinal; Drake Morgan; Elio Acquas; Richard W Foltin; Paul Vezina; S Stevens Negus; jose antonio crespo; Petra Stöckl; Petra Grubinger; Ekkehard Madlung; Christian Haring; Martin Kurz; Alois Saria
Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests.
Pharmacology 2007;80(2-3):65-119.
2006: Nancy K Mello; S Stevens Negus; Kenner C Rice; Jack H Mendelson
Effects of the CRF1 antagonist antalarmin on cocaine self-administration and discrimination in rhesus monkeys.
Pharmacology, biochemistry, and behavior 2006;85(4):744-51.
2006: S Stevens Negus; T W Vanderah; Michael R Brandt; E J Bilsky; Lino Becerra; David Borsook
Preclinical assessment of candidate analgesic drugs: recent advances and future challenges.
The Journal of pharmacology and experimental therapeutics 2006;319(2):507-14.
2006: Gail Pereira Do Carmo; Nancy K Mello; Kenner C Rice; John E Folk; S Stevens Negus
Effects of the selective delta opioid agonist SNC80 on cocaine- and food-maintained responding in rhesus monkeys.
European journal of pharmacology 2006;547(1-3):92-100.
2006: Ingela Danielsson; Maciej Gasior; Glenn W Stevenson; John E Folk; Kenner C Rice; S Stevens Negus
Electroencephalographic and convulsant effects of the delta opioid agonist SNC80 in rhesus monkeys.
Pharmacology, biochemistry, and behavior 2006;85(2):428-34.
2006: S Stevens Negus
Some implications of receptor theory for in vivo assessment of agonists, antagonists and inverse agonists.
Biochemical pharmacology 2006;71(12):1663-70.
2006: Glenn W Stevenson; Edward J Bilsky; S Stevens Negus
Targeting pain-suppressed behaviors in preclinical assays of pain and analgesia: effects of morphine on acetic acid-suppressed feeding in C57BL/6J mice.
The journal of pain : official journal of the American Pain Society 2006;7(6):408-16.
2006: Jolan M Terner; Andrew C Barrett; Lisa M Lomas; S Stevens Negus; Mitchell J Picker
Influence of low doses of naltrexone on morphine antinociception and morphine tolerance in male and female rats of four strains.
Pain 2006;122(1-2):90-101.
2006: S Stevens Negus
Choice between heroin and food in nondependent and heroin-dependent rhesus monkeys: effects of naloxone, buprenorphine, and methadone.
The Journal of pharmacology and experimental therapeutics 2006;317(2):711-23.
2006: S Stevens Negus
Brief history of the Drug Evaluation Committee (DEC) and its role in the college on problems of drug dependence.
Drug and alcohol dependence 2006;82(2):182-3.
2005: Megan E Roth; S Stevens Negus; Inge M Knudson; Melanie P Burgess; Nancy K Mello
Effects of gender and menstrual cycle phase on food-maintained responding under a progressive-ratio schedule in cynomolgus monkeys.
Pharmacology, biochemistry, and behavior 2005;82(4):735-43.
2005: Jennifer L Mathews; Xuemei Peng; Wennan Xiong; Ao Zhang; S Stevens Negus; John L Neumeyer; Jean M Bidlack
Characterization of a novel bivalent morphinan possessing kappa agonist and micro agonist/antagonist properties.
The Journal of pharmacology and experimental therapeutics 2005;315(2):821-7.
2005: Andrew C Barrett; S Stevens Negus; Nancy K Mello; S Barak Caine
Effect of GABA agonists and GABA-A receptor modulators on cocaine- and food-maintained responding and cocaine discrimination in rats.
The Journal of pharmacology and experimental therapeutics 2005;315(2):858-71.
2005: S Stevens Negus
Effects of punishment on choice between cocaine and food in rhesus monkeys.
Psychopharmacology 2005;181(2):244-52.
2005: Glenn W Stevenson; John E Folk; Kenner C Rice; S Stevens Negus
Interactions between delta and mu opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: studies with SNC80 [(+)-4-[(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide] and heroin.
The Journal of pharmacology and experimental therapeutics 2005;314(1):221-31.
2005: Richard B Rothman; Bruce E Blough; William L Woolverton; Karen G Anderson; S Stevens Negus; Nancy K Mello; Bryan L Roth; Michael H Baumann
Development of a rationally designed, low abuse potential, biogenic amine releaser that suppresses cocaine self-administration.
The Journal of pharmacology and experimental therapeutics 2005;313(3):1361-9.
2005: S Stevens Negus
Interactions between the reinforcing effects of cocaine and heroin in a drug-vs-food choice procedure in rhesus monkeys: a dose-addition analysis.
Psychopharmacology 2005;180(1):115-24.
2004: Glenn W Stevenson; Mark P Wentland; Jean M Bidlack; Nancy K Mello; S Stevens Negus
Effects of the mixed-action kappa/mu opioid agonist 8-carboxamidocyclazocine on cocaine- and food-maintained responding in rhesus monkeys.
European journal of pharmacology 2004;506(2):133-41.
2004: Nancy K Mello; Jack H Mendelson; S Stevens Negus; Maureen Kelly; Inge M Knudson; Megan E Roth
The effects of cocaine on gonadal steroid hormones and LH in male and female rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(11):2024-34.
2004: S Stevens Negus
Effects of the kappa opioid agonist U50,488 and the kappa opioid antagonist nor-binaltorphimine on choice between cocaine and food in rhesus monkeys.
Psychopharmacology 2004;176(2):204-13.
2004: John Grabowski; James Shearer; John Merrill; S Stevens Negus
Agonist-like, replacement pharmacotherapy for stimulant abuse and dependence.
Addictive behaviors 2004;29(7):1439-64.
2004: S Stevens Negus; Nancy K Mello
Effects of chronic methadone treatment on cocaine- and food-maintained responding under second-order, progressive-ratio and concurrent-choice schedules in rhesus monkeys.
Drug and alcohol dependence 2004;74(3):297-309.
2004: S Barak Caine; Carrie A Bowen; Gloria Yu; David Zuzga; S Stevens Negus; Nancy K Mello
Effect of gonadectomy and gonadal hormone replacement on cocaine self-administration in female and male rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(5):929-42.
2004: S Stevens Negus; Brooke A Wurrey; Nancy K Mello
Sex differences in thermal nociception and prostaglandin-induced thermal hypersensitivity in rhesus monkeys.
The journal of pain : official journal of the American Pain Society 2004;5(2):92-103.
2004: Daniela E Rusovici; S Stevens Negus; Nancy K Mello; Jean M Bidlack
Kappa-opioid receptors are differentially labeled by arylacetamides and benzomorphans.
European journal of pharmacology 2004;485(1-3):119-25.
2004: Nancy K Mello; Jack H Mendelson; S Stevens Negus; Maureen Kelly
Ovarian steroid hormone modulation of the acute effects of cocaine on luteinizing hormone and prolactin levels in ovariectomized rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2004;308(1):156-67.
2003: Glenn W Stevenson; John E Folk; David C Linsenmayer; Kenner C Rice; S Stevens Negus
Opioid interactions in rhesus monkeys: effects of delta + mu and delta + kappa agonists on schedule-controlled responding and thermal nociception.
The Journal of pharmacology and experimental therapeutics 2003;307(3):1054-64.
2003: John L Neumeyer; Ao Zhang; Wennan Xiong; Xiao-Hui Gu; James E Hilbert; Brian I Knapp; S Stevens Negus; Nancy K Mello; Jean M Bidlack
Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors.
Journal of medicinal chemistry 2003;46(24):5162-70.
2003: Carrie A Bowen; S Stevens Negus; Rushi Zong; John L Neumeyer; Jean M Bidlack; Nancy K Mello
Effects of mixed-action kappa/mu opioids on cocaine self-administration and cocaine discrimination by rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(6):1125-39.
2003: S Stevens Negus; Nancy K Mello
Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a second-order schedule in rhesus monkeys.
Drug and alcohol dependence 2003;70(1):39-52.
2003: S Stevens Negus; Michael R Brandt; Michael B Gatch; Nancy K Mello
Effects of heroin and its metabolites on schedule-controlled responding and thermal nociception in rhesus monkeys: sensitivity to antagonism by quadazocine, naltrindole and beta-funaltrexamine.
Drug and alcohol dependence 2003;70(1):17-27.
2003: S Stevens Negus; Nancy K Mello
Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a progressive-ratio schedule in rhesus monkeys.
Psychopharmacology 2003;167(3):324-32.
2003: S Stevens Negus
Rapid assessment of choice between cocaine and food in rhesus monkeys: effects of environmental manipulations and treatment with d-amphetamine and flupenthixol.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(5):919-31.
2002: S Stevens Negus; J M Bidlack; Nancy K Mello; MS Furness; Kenner C Rice; Michael R Brandt
Delta opioid antagonist effects of buprenorphine in rhesus monkeys.
Behavioural pharmacology 2002;13(7):557-70.
2002: S Stevens Negus; Nancy K Mello; David C Linsenmayer; R M Jones; Philip S Portoghese
Kappa opioid antagonist effects of the novel kappa antagonist 5'-guanidinonaltrindole (GNTI) in an assay of schedule-controlled behavior in rhesus monkeys.
Psychopharmacology 2002;163(3-4):412-9.
2002: Carrie A Bowen; Bradford D Fischer; Nancy K Mello; S Stevens Negus
Antagonism of the antinociceptive and discriminative stimulus effects of heroin and morphine by 3-methoxynaltrexone and naltrexone in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2002;302(1):264-73.
2002: S Stevens Negus; David S Zuzga; Nancy K Mello
Sex differences in opioid antinociception in rhesus monkeys: antagonism of fentanyl and U50,488 by quadazocine.
The journal of pain : official journal of the American Pain Society 2002;3(3):218-26.
2002: S Barak Caine; S Stevens Negus; Nancy K Mello; Smita Patel; Linda J Bristow; Janusz Kulagowski; Daniela Vallone; Adolfo Saiardi; Emiliana Borrelli
Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2977-88.
2002: Carrie A Bowen; S Stevens Negus; Maureen Kelly; Nancy K Mello
The effects of heroin on prolactin levels in male rhesus monkeys: use of cumulative-dosing procedures.
Psychoneuroendocrinology 2002;27(3):319-36.
2002: S Stevens Negus; Nancy K Mello
Effects of mu-opioid agonists on cocaine- and food-maintained responding and cocaine discrimination in rhesus monkeys: role of mu-agonist efficacy.
The Journal of pharmacology and experimental therapeutics 2002;300(3):1111-21.
2002: S Stevens Negus; Nancy K Mello
Effects of gonadal steroid hormone treatments on opioid antinociception in ovariectomized rhesus monkeys.
Psychopharmacology 2002;159(3):275-83.
2001: Michael R Brandt; MS Furness; Kenner C Rice; B D Fischer; S Stevens Negus
Studies of tolerance and dependence with the delta-opioid agonist SNC80 in rhesus monkeys responding under a schedule of food presentation.
The Journal of pharmacology and experimental therapeutics 2001;299(2):629-37.
2001: John L Neumeyer; Xiao-Hui Gu; L A van Vliet; N J DeNunzio; D E Rusovici; D J Cohen; S Stevens Negus; Nancy K Mello; Jean M Bidlack
Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan.
Bioorganic & medicinal chemistry letters 2001;11(20):2735-40.
2001: Nancy K Mello; S Stevens Negus
Effects of indatraline and buprenorphine on self-administration of speedball combinations of cocaine and heroin by rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(1):104-17.
2001: Michael R Brandt; MS Furness; Nancy K Mello; Kenner C Rice; S Stevens Negus
Antinociceptive effects of delta-opioid agonists in Rhesus monkeys: effects on chemically induced thermal hypersensitivity.
The Journal of pharmacology and experimental therapeutics 2001;296(3):939-46.
2000: S Stevens Negus; Nancy K Mello; P A Fivel
Effects of GABA agonists and GABA-A receptor modulators on cocaine discrimination in rhesus monkeys.
Psychopharmacology 2000;152(4):398-407.
2000: S Barak Caine; S Stevens Negus; Nancy K Mello; Jack Bergman
Effects of dopamine D1-like and D2-like agonists in rats trained to discriminate cocaine from saline: influence of experimental history.
Experimental and clinical psychopharmacology 2000;8(3):404-14.
2000: John L Neumeyer; Nancy K Mello; S Stevens Negus; Jean M Bidlack
Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse.
Pharmaceutica acta Helvetiae 2000;74(2-3):337-44.
2000: John L Neumeyer; Jean M Bidlack; Rushi Zong; V Bakthavachalam; P Gao; D J Cohen; S Stevens Negus; Nancy K Mello
Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence.
Journal of medicinal chemistry 2000;43(1):114-22.
2000: Nancy K Mello; S Stevens Negus
Interactions between kappa opioid agonists and cocaine. Preclinical studies.
Annals of the New York Academy of Sciences 2000;909():104-32.
2000: S Barak Caine; S Stevens Negus; Nancy K Mello
Effects of dopamine D(1-like) and D(2-like) agonists on cocaine self-administration in rhesus monkeys: rapid assessment of cocaine dose-effect functions.
Psychopharmacology 2000;148(1):41-51.
1999: S Barak Caine; S Stevens Negus; Nancy K Mello
Method for training operant responding and evaluating cocaine self-administration behavior in mutant mice.
Psychopharmacology 1999;147(1):22-4.
1999: S Barak Caine; S Stevens Negus; Nancy K Mello; Jack Bergman
Effects of dopamine D(1-like) and D(2-like) agonists in rats that self-administer cocaine.
The Journal of pharmacology and experimental therapeutics 1999;291(1):353-60.
1999: S Stevens Negus; Michael R Brandt; Nancy K Mello
Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1999;291(1):60-9.
1999: Nancy K Mello; S Stevens Negus
Effects of flupenthixol and quadazocine on self-administration of speedball combinations of cocaine and heroin by rhesus monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(4):575-88.
1999: Michael R Brandt; S Stevens Negus; Nancy K Mello; MS Furness; X Zhang; Kenner C Rice
Discriminative stimulus effects of the nonpeptidic delta-opioid agonist SNC80 in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1157-64.
1999: S Stevens Negus; Nancy K Mello
Opioid antinociception in ovariectomized monkeys: comparison with antinociception in males and effects of estradiol replacement.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1132-40.
1999: Michael B Gatch; S Stevens Negus; Nancy K Mello
Antinociceptive effects of cocaine in rhesus monkeys.
Pharmacology, biochemistry, and behavior 1999;62(2):291-7.
1998: Nancy K Mello; S Stevens Negus
Effects of kappa opioid agonists on cocaine- and food-maintained responding by rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1998;286(2):812-24.
1998: S Stevens Negus; Michael B Gatch; Nancy K Mello; X Zhang; K Rice
Behavioral effects of the delta-selective opioid agonist SNC80 and related compounds in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1998;286(1):362-75.
1998: X Lamas; S Stevens Negus; Michael B Gatch; Nancy K Mello
Effects of heroin/cocaine combinations in rats trained to discriminate heroin or cocaine from saline.
Pharmacology, biochemistry, and behavior 1998;60(2):357-64.
1998: S Stevens Negus; Michael B Gatch; Nancy K Mello
Discriminative stimulus effects of a cocaine/heroin "speedball" combination in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1998;285(3):1123-36.
1998: Nancy K Mello; S Stevens Negus
The effects of buprenorphine on self-administration of cocaine and heroin "speedball" combinations and heroin alone by rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1998;285(2):444-56.
1998: S Stevens Negus; Michael B Gatch; Nancy K Mello
Effects of mu opioid agonists alone and in combination with cocaine and D-amphetamine in rhesus monkeys trained to discriminate cocaine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;18(5):325-38.
1998: Gregory I Elmer; Jeanne O Pieper; S Stevens Negus; James H Woods
Genetic variance in nociception and its relationship to the potency of morphine-induced analgesia in thermal and chemical tests.
Pain 1998;75(1):129-40.
1998: Michael B Gatch; S Stevens Negus; Nancy K Mello
Antinociceptive effects of monoamine reuptake inhibitors administered alone or in combination with mu opioid agonists in rhesus monkeys.
Psychopharmacology 1998;135(1):99-106.
1997: S Stevens Negus; Nancy K Mello; Philip S Portoghese; C E Lin
Effects of kappa opioids on cocaine self-administration by rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1997;282(1):44-55.
1996: Michael B Gatch; S Stevens Negus; Nancy K Mello; S Archer; J M Bidlack
Effects of the structurally novel opioid 14 alpha, 14' beta-[dithiobis [(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydromorphinone) on schedule-controlled behavior and thermal nociception in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1282-9.
1996: S Stevens Negus; Drake Morgan; charlie cook; Mitchell J Picker
Effects of the delta opioid against BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure.
Psychopharmacology 1996;126(3):199-205.
1996: S Stevens Negus; Nancy K Mello; X Lamas; Jack H Mendelson
Acute and chronic effects of flupenthixol on the discriminative stimulus and reinforcing effects of cocaine in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1996;278(2):879-90.
1996: Nancy K Mello; S Stevens Negus
Preclinical evaluation of pharmacotherapies for treatment of cocaine and opioid abuse using drug self-administration procedures.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;14(6):375-424.
1996: X Lamas; S Stevens Negus; M A Nader; Nancy K Mello
Effects of the putative dopamine D3 receptor agonist 7-OH-DPAT in rhesus monkeys trained to discriminate cocaine from saline.
Psychopharmacology 1996;124(4):306-14.
1996: Michael B Gatch; A Liguori; S Stevens Negus; Nancy K Mello; J Bergman; T Liguori
Naloxonazine antagonism of levorphanol-induced antinociception and respiratory depression in rhesus monkeys.
European journal of pharmacology 1996;298(1):31-6.
1996: Eduardo R Butelman; S Stevens Negus; John W Lewis; James H Woods
Clocinnamox antagonism of opioid suppression of schedule-controlled responding in rhesus monkeys.
Psychopharmacology 1996;123(4):320-4.
1995: Michael B Gatch; S Stevens Negus; Eduardo R Butelman; Nancy K Mello
Antinociceptive effects of cocaine/opioid combinations in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1995;275(3):1346-54.
1995: X Lamas; S Stevens Negus; E Hall; Nancy K Mello
Relationship between the discriminative stimulus effects and plasma concentrations of intramuscular cocaine in rhesus monkeys.
Psychopharmacology 1995;121(3):331-8.
1995: Nancy K Mello; S Stevens Negus; Scott E Lukas; Jack H Mendelson; J W Sholar; J Drieze
A primate model of polydrug abuse: cocaine and heroin combinations.
The Journal of pharmacology and experimental therapeutics 1995;274(3):1325-37.
1995: S Stevens Negus; Eduardo R Butelman; Michael B Gatch; James H Woods
Effects of morphine and ketorolac on thermal allodynia induced by prostaglandin E2 and bradykinin in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1995;274(2):805-14.
1995: S Stevens Negus; Nancy K Mello; P S Portoghese; Scott E Lukas; Jack H Mendelson
Role of delta opioid receptors in the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1245-56.
1995: Eduardo R Butelman; S Stevens Negus; Michael B Gatch; K J Chang; James H Woods
BW373U86, a delta-opioid receptor agonist, reverses bradykinin-induced thermal allodynia in rhesus monkeys.
European journal of pharmacology 1995;277(2-3):285-7.
1994: Gail Winger; Sevil Yasar; S Stevens Negus; S R Goldberg
Intravenous self-administration studies with l-deprenyl (selegiline) in monkeys.
Clinical pharmacology and therapeutics 1994;56(6 Pt 2):774-80.
1994: S Stevens Negus; Eduardo R Butelman; K J Chang; B DeCosta; Gail Winger; James H Woods
Behavioral effects of the systemically active delta opioid agonist BW373U86 in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1994;270(3):1025-34.
1994: Jillian H Broadbear; S Stevens Negus; Eduardo R Butelman; B R de Costa; James H Woods
Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on kappa-opioid agonists in the mouse writhing assay.
Psychopharmacology 1994;115(3):311-9.
1993: Eduardo R Butelman; S Stevens Negus; Y Ai; B R de Costa; James H Woods
Kappa opioid antagonist effects of systemically administered nor-binaltorphimine in a thermal antinociception assay in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1993;267(3):1269-76.
1993: S Stevens Negus; T F Burke; F Medzihradsky; James H Woods
Effects of opioid agonists selective for mu, kappa and delta opioid receptors on schedule-controlled responding in rhesus monkeys: antagonism by quadazocine.
The Journal of pharmacology and experimental therapeutics 1993;267(2):896-903.
1993: S Stevens Negus; Eduardo R Butelman; Y Al; James H Woods
Prostaglandin E2-induced thermal hyperalgesia and its reversal by morphine in the warm-water tail-withdrawal procedure in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1355-63.
1992: Mitchell J Picker; R M Craft; S Stevens Negus; K R Powell; adande mattox; S R Jones; B K Hargrove; Linda A Dykstra
Intermediate efficacy mu opioids: examination of their morphine-like stimulus effects and response rate-decreasing effects in morphine-tolerant rats.
The Journal of pharmacology and experimental therapeutics 1992;263(2):668-81.
1991: Mitchell J Picker; S Stevens Negus; K R Powell
Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation.
Psychopharmacology 1991;103(1):129-35.
1991: S Stevens Negus; Mitchell J Picker; Linda A Dykstra
Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey.
The Journal of pharmacology and experimental therapeutics 1991;256(1):149-58.
1990: Mitchell J Picker; S Stevens Negus; R M Craft
Butorphanol's efficacy at mu and kappa opioid receptors: inferences based on the schedule-controlled behavior of nontolerant and morphine-tolerant rats and on the responding of rats under a drug discrimination procedure.
Pharmacology, biochemistry, and behavior 1990;36(3):563-8.
1990: Mitchell J Picker; P Doty; S Stevens Negus; adande mattox; Linda A Dykstra
Discriminative stimulus properties of U50,488 and morphine: effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists.
The Journal of pharmacology and experimental therapeutics 1990;254(1):13-22.
1990: S Stevens Negus; M J Picker; Linda A Dykstra
Interactions between mu and kappa opioid agonists in the rat drug discrimination procedure.
Psychopharmacology 1990;102(4):465-73.
1989: Mitchell J Picker; S Stevens Negus; Linda A Dykstra
Opioid-like discriminative stimulus properties of benzomorphans in the pigeon: stereospecificity and differential substitution patterns.
Life sciences 1989;45(18):1637-45.
1989: S Stevens Negus; M J Picker; L A Dykstra
Kappa antagonist effects of buprenorphine in the rat drug-discrimination procedure.
NIDA research monograph 1989;95():518-9.
1989: S Stevens Negus; M J Picker; Linda A Dykstra
Kappa antagonist properties of buprenorphine in non-tolerant and morphine-tolerant rats.
Psychopharmacology 1989;98(1):141-3.
1988: S Stevens Negus; Linda A Dykstra
Kappa antagonist properties of buprenorphine in the shock titration procedure.
European journal of pharmacology 1988;156(1):77-86.